Abstract: An improved fluid collection tube assembly, particularly adapted for collecting blood or other biological fluid, includes a plastic collection tube having a forward end closed by a rubber diaphragm and an open rear end. A resilient piston member is slidably disposed within the tube in sealing engagement with the interior wall of the tube and is spaced forwardly from the open rear end. Prior to collecting a biological fluid from a patient, ambient air is in the space between the closed forward end of the tube and the piston member. When it is desired to collect a biological fluid from a patient, the piston is drawn rearwardly into the rear end of the tube to create a vacuum in the tube between the rubber diaphragm and the piston member.

Abstract: A syringe or other container which may be prefilled with a parenteral drug has an end closed by a pierceable seal that is engaged between the end of the syringe barrel and a plastic sealing cap. A coupling member is disposed for sliding movement on the cap. The coupling member has a pointed end for piercing the seal, and a luer coupling portion at the opposite end for connection with a coupling element associated with another device, such as a catheter or needle cannula.

Abstract: A container having a sealed chamber for receiving an ampule containing a parenteral solution. The container device has a luer tapered connector for connection with a luer tapered coupling element of another device, such as a hypodermic syringe barrel tip. Between the connector and the chamber is a filter for filtering the parenteral solution as it is discharged from the ampule. The container device may be formed of a pliable material such that a glass ampule within the chamber can be broken by hand-squeezing the container. The container may also be formed of a pair of relatively rigid threadedly coupled members with a glass ampule between the members and such that the two members can be rotated to move the members together and break the glass ampule. The container device may also be provided with a pair of threadedly coupled upper and lower relatively rigid members having a seal on the interior of the upper member engaged with the open end of the ampule.