Patents by Inventor Elsebe Geraldine Overbeek-Klumpers

Elsebe Geraldine Overbeek-Klumpers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-cyanoquinolines as inhibitors of EGF-R and HER2 kinases
    Patent number: 6821988
    Abstract: This invention provides compounds of Formula (I), represented by the structure wherein G1, G2, G3, G4, Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of polycystic kidney disease.
    Type: Grant
    Filed: November 26, 2002
    Date of Patent: November 23, 2004
    Assignee: Wyeth Holdings Corporation
    Inventors: Allan Wissner, Hwei-Ru Tsou, Middleton Brawner Floyd, Jr., Bernard D. Johnson, Elsebe Geraldine Overbeek-Klumpers
  • 3-Cyanoquinolines,3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
    Publication number: 20040176602
    Abstract: This invention provides compounds of Formula (I), having the structure 1
    Type: Application
    Filed: January 9, 2004
    Publication date: September 9, 2004
    Applicant: Wyeth
    Inventors: Diane Harris Boschelli, Yanong Wang, Frank Charles Boschelli, Dan Maarten Berger, Nan Zhang, Dennis William Powell, Fei Ye, Ayako Yamashita, Frenel Fils DeMorin, Biqi Wu, Hwei-Ru Tsou, Elsebe Geraldine Overbeek-Klumpers, Allan Wissner
  • 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
    Patent number: 6689772
    Abstract: This invention provides compounds of Formula (I), having the structure where T, Z, X, A, R1, R2a, R2b, R2c, R3, R4, and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of osteoporosis and polycystic kidney disease.
    Type: Grant
    Filed: December 12, 2002
    Date of Patent: February 10, 2004
    Assignee: Wyeth
    Inventors: Diane Harris Boschelli, Yanong Wang, Frank Charles Boschelli, Dan Maarten Berger, Nan Zhang, Dennis William Powell, Fei Ye, Ayako Yamashita, Frenel Fils DeMorin, Biqi Wu, Hwei-Ru Tsou, Elsebe Geraldine Overbeek-Klumpers, Allan Wissner
  • Tricyclic protein kinase inhibitors
    Patent number: 6608048
    Abstract: This invention provides compounds of Formula (I), where A″, Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of polycystic kidney disease.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: August 19, 2003
    Assignee: Wyeth Holdings
    Inventors: Hwei-Ru Tsou, Elsebe Geraldine Overbeek-Klumpers, Allan Wissner
  • 3-cyanoquinolines as inhibitors of EGF-R and HER2 kinases
    Publication number: 20030149056
    Abstract: This invention provides compounds of Formula (I), represented by the structure 1
    Type: Application
    Filed: November 26, 2002
    Publication date: August 7, 2003
    Applicant: American Cyanamid Company
    Inventors: Allan Wissner, Hwei-Ru Tsou, Middleton Brawner Floyd, Bernard D. Johnson, Elsebe Geraldine Overbeek-Klumpers
  • Tricyclic protein kinase inhibitors
    Publication number: 20030065180
    Abstract: This invention provides compounds of Formula (I), 1
    Type: Application
    Filed: March 28, 2001
    Publication date: April 3, 2003
    Applicant: American Home Products Corporation
    Inventors: Hwei-Ru Tsou, Elsebe Geraldine Overbeek-Klumpers, Allan Wissner
  • 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
    Patent number: 6521618
    Abstract: This invention provides compounds of Formula (I), having the structure where T, Z, X, A, R1, R2a, R2b, R2c, R3, R4, and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of osteoporosis and polycystic kidney disease.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: February 18, 2003
    Assignee: Wyeth
    Inventors: Diane Harris Boschelli, Yanong Wang, Frank Charles Boschelli, Dan Maarten Berger, Nan Zhang, Dennis William Powell, Fei Ye, Ayako Yamashita, Frenel Fils DeMorin, Biqi Wu, Hwei-Ru Tsou, Elsebe Geraldine Overbeek-Klumpers, Allan Wissner
  • 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
    Publication number: 20020026052
    Abstract: This invention provides compounds of Formula (I), having the structure 1
    Type: Application
    Filed: March 28, 2001
    Publication date: February 28, 2002
    Applicant: American Home Products Corporation
    Inventors: Diane Harris Boschelli, Yanong Wang, Frank Charles Boschelli, Dan Maarten Berger, Nan Zhang, Dennis William Powell, Fei Ye, Ayako Yamashita, Frenel Fils Demorin, Biqi Wu, Hwei-Ru Tsou, Elsebe Geraldine Overbeek-Klumpers, Allan Wissner