Patents by Inventor Elton Fabian MOLINA SOTO

Elton Fabian MOLINA SOTO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Green methodology to create polymeric nanocarriers containing hydrophilic low molecular-weight drugs and providing a very high drug loading and a very high prolonged release
    Patent number: 11413349
    Abstract: In one aspect, provided herein is a nanocarrier composition for formulating a hydrophilic and aromatic low molecular-weight drug (HALMD), the composition comprising: an aromatic polymer; and a hydrophilic and aromatic low molecular-weight drug (HALMD); wherein the aromatic polymer has a positive or negative charge or is a zwitterion, and the hydrophilic and aromatic low molecular-weight drug (HALMD) has an opposing positive or negative charge or is a zwitterion; and wherein the composition has a size of between 50-400 nm and optionally, a zeta potential of from +100 to ?100 mV. A method for preparing the nanocarrier composition, as well as pharmaceutical compositions and therapeutic uses thereof, are also disclosed.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: August 16, 2022
    Assignees: UNIVERSIDAD DE CHILE, UNIVERSIDAD AUSTRAL DE CHILE
    Inventors: Felipe Andrés Oyarzún Ampuero, Ignacio Moreno Villoslada, Maria Gabriela Villamizar Sarmiento, Elton Fabian Molina Soto
  • NANOCARRIER FORMULATION OF AROMATIC DRUGS
    Publication number: 20200376127
    Abstract: In one aspect, provided herein is a nanocarrier composition for formulating a hydrophilic and aromatic low molecular-weight drug (HALMD), the composition comprising: an aromatic polymer; and a hydrophilic and aromatic low molecular-weight drug (HALMD); wherein the aromatic polymer has a positive or negative charge or is a zwitterion, and the hydrophilic and aromatic low molecular-weight drug (HALMD) has an opposing positive or negative charge or is a zwitterion; and wherein the composition has a size of between 50-400 nm and optionally, a zeta potential of from +100 to ?100 mV. A method for preparing the nanocarrier composition, as well as pharmaceutical compositions and therapeutic uses thereof, are also disclosed.
    Type: Application
    Filed: May 29, 2020
    Publication date: December 3, 2020
    Inventors: Felipe Andrés OYARZÚN AMPUERO, Ignacio MORENO VILLOSLADA, María Gabriela VILLAMIZAR SARMIENTO, Elton Fabian MOLINA SOTO