Patents by Inventor Elyse Bourque

Elyse Bourque has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GPR84 antagonists and uses thereof
    Patent number: 12617777
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.
    Type: Grant
    Filed: February 2, 2022
    Date of Patent: May 5, 2026
    Assignee: Liminal BioSciences Limited
    Inventors: Shaun Abbott, Mylène De Léséleuc, Julien Martel, Elyse Bourque, Jeremy Green, Alexandre Larivée, Jean-Benoìt Giguère, Elodie Landagaray, Claudio Sturino, Nadia Michel Nasser
  • SUBSTITUTED PYRIDONE GPR84 ANTAGONISTS AND USES THEREOF
    Publication number: 20260055117
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.
    Type: Application
    Filed: August 2, 2023
    Publication date: February 26, 2026
    Inventors: Shaun Abbott, Mylène De Léséleuc, Julien Martel, Elyse Bourque, Jeremy Green
  • HETEROARYL CARBOXAMIDE AND RELATED GPR84 ANTAGONISTS AND USES THEREOF
    Publication number: 20260028330
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.
    Type: Application
    Filed: August 2, 2023
    Publication date: January 29, 2026
    Inventors: Shaun Abbott, Mylène De Lèsèleuc, Julien Martel, ELYSE Bourque, Jeremy Green, Nadia Michel Nasser
  • GPR84 ANTAGONISTS AND USES THEREOF
    Publication number: 20250340543
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.
    Type: Application
    Filed: July 10, 2025
    Publication date: November 6, 2025
    Inventors: Shaun Abbott, Mylène De Léséleuc, Julien Martel, Elyse Bourque, Jeremy Green, Alexandre Larivée, Jean-Benoit Giguère, Elodie Landangaray, Claudio Sturino
  • GPR84 antagonists and uses thereof
    Patent number: 12378229
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.
    Type: Grant
    Filed: February 2, 2022
    Date of Patent: August 5, 2025
    Assignee: Liminal BioSciences Limited
    Inventors: Shaun Abbott, Mylène De Léséleuc, Julien Martel, Elyse Bourque, Jeremy Green, Alexandre Larivée, Jean-Benoǐt Giguère, Elodie Landagaray, Claudio Sturino
  • OXER1 ANTAGONISTS AND USES THEREOF
    Publication number: 20250154145
    Abstract: Disclosed are compounds of formula (I), wherein ring A is an 8-10 membered aromatic or partially aromatic bicyclic ring having 1-4 heteroatoms compositions thereof, wherein L1, L2, R1 to R4 and m are as defined in claim 1; and methods of using the same for antagonizing G-protein coupled receptor OXER1, and for treating of OXER1-mediated disorders, such as asthma or cancer.
    Type: Application
    Filed: December 20, 2022
    Publication date: May 15, 2025
    Inventors: Shaun Abbott, Jeremy Green, Elyse Bourque, Mylène De Léséleuc, Julien Martel
  • GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
    Publication number: 20250026749
    Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.
    Type: Application
    Filed: July 19, 2024
    Publication date: January 23, 2025
    Applicant: Genzyme Corporation
    Inventors: Elyse BOURQUE, Mario A. CABRERA-SALAZAR, Cassandra CELATKA, Seng H. CHENG, Bradford HIRTH, Andrew GOOD, Katherine JANCSICS, John MARSHALL, Markus METZ, Ronald K. SCHEULE, Renato SKERLJ, Yibin XIANG, Zhong ZHAO, John LEONARD, Thomas NATOLI, Elina MAKINO, Herve HUSSON, Oxana BESKROVNAYA
  • Glucosylceramide synthase inhibitors
    Patent number: 12060349
    Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS) of the Formula I: represented by the following structural formula or a pharmaceutically acceptable salt thereof, wherein the variables are as defined herein, useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: August 13, 2024
    Assignee: GENZYME CORPORATION
    Inventors: Elyse Bourque, Mario A. Cabrera-Salazar, Cassandra Celatka, Seng H. Cheng, Bradford Hirth, Andrew Good, Katherine Jancsics, John Marshall, Markus Metz, Ronald K. Scheule, Renato Skerlj, Yibin Xiang, Zhong Zhao, John Leonard, Thomas Natoli, Elina Makino, Herve Husson, Oxana Beskrovnaya
  • GPR84 ANTAGONISTS AND USES THEREOF
    Publication number: 20230113202
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.
    Type: Application
    Filed: February 2, 2022
    Publication date: April 13, 2023
    Inventors: Shaun ABBOTT, Mylène DeLESELEUC, Julien MARTEL, Elyse BOURQUE, Jeremy GREEN, Alexandre LARIVÉE, Jean-Benoìt GIGUÈRE, Elodie LANDAGARAY, Claudio STURINO, Nadia Michel NASSER
  • GPR84 ANTAGONISTS AND USES THEREOF
    Publication number: 20230091528
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.
    Type: Application
    Filed: February 2, 2022
    Publication date: March 23, 2023
    Inventors: Shaun ABBOTT, Mylène DeLESELEUC, Julien MARTEL, Elyse BOURQUE, Jeremy GREEN, Alexandre LARIVÉE, Jean-Benoît GIGUÈRE, Elodie LANDAGARAY, Claudio STURINO
  • COMPOUNDS, POLYMERS, DEVICES, AND USES THEREOF
    Publication number: 20230045277
    Abstract: Described herein are compounds of Formula (I), polymers and implantable elements comprising compounds of Formula (II), and compositions and methods of use thereof. In particular, the compounds, modified polymers, implantable elements and related compositions may be used in methods for the prevention and treatment of a disease, disorder or condition in a subject.
    Type: Application
    Filed: December 11, 2020
    Publication date: February 9, 2023
    Inventors: Elyse Bourque, Richard Heidebrecht, Christopher P. Hencken
  • GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
    Publication number: 20220073508
    Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.
    Type: Application
    Filed: April 14, 2021
    Publication date: March 10, 2022
    Applicant: Genzyme Corporation
    Inventors: Elyse BOURQUE, Mario A. CABRERA-SALAZAR, Cassandra CELATKA, Seng H. CHENG, Bradford HIRTH, Andrew GOOD, Katherine JANCSICS, John MARSHALL, Markus METZ, Ronald K. SCHEULE, Renato SKERLJ, Yibin XIANG, Zhong ZHAO, John LEONARD, Thomas NATOLI, Elina MAKINO, Herve HUSSON, Oxana BESKROVNAYA
  • HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF RSV
    Publication number: 20210403444
    Abstract: Disclosed herein are compounds and compositions for treating or inhibiting RSV and related members of the pneumovirus and paramyxovirus families such as human metapneumovirus, mumps virus, human parainfluenzaviruses, and Nipah and hendra virus, and methods of treatment or prevention thereof.
    Type: Application
    Filed: July 8, 2021
    Publication date: December 30, 2021
    Inventors: Richard K. PLEMPER, Eddy LEE, John VERNACHIO, Elyse BOURQUE
  • GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
    Publication number: 20210261557
    Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.
    Type: Application
    Filed: April 27, 2021
    Publication date: August 26, 2021
    Applicant: GENZYME CORPORATION
    Inventors: Elyse BOURQUE, Mario CABRERA-SALAZAR, Cassandra CELATKA, Seng CHENG, Mary A. CROMWELL, Andrew GOOD, Bradford HIRTH, Katherine JANCSICS, John P. LEONARD, Lingyun LI, James LILLIE, Hanlan LIU, Elina MAKINO, John MARSHALL, Paul MASON, Markus METZ, Fazeela MORSHED, Thomas O'SHEA, Ronald SCHEULE, Renato SKERLJ, Bing WANG, Yibin XIANG, Zhong ZHAO
  • Heterocyclic derivatives for the treatment of RSV
    Patent number: 11084796
    Abstract: Disclosed herein are compounds and compositions for treating or inhibiting RSV and related members of the pneumovirus and paramyxovirus families such as human metapneumovirus, mumps virus, human parainfluenzaviruses, and Nipah and hendra virus, and methods of treatment or prevention thereof.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: August 10, 2021
    Assignee: GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Richard K. Plemper, Eddy Lee, John Vernachio, Elyse Bourque
  • Glucosylceramide synthase inhibitors
    Patent number: 11008316
    Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS), such as Compound of Formula I, shown below, as defined herein, useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: May 18, 2021
    Assignee: GENZYME CORPORATION
    Inventors: Elyse Bourque, Mario A. Cabrera-Salazar, Cassandra Celatka, Seng H. Cheng, Bradford Hirth, Andrew Good, Katherine Jancsics, John Marshall, Markus Metz, Ronald K. Scheule, Renato Skerlj, Yibin Xiang, Zhong Zhao, John Leonard, Thomas Natoli, Elina Makino, Herve Husson, Oxana Beskrovnaya
  • Bicyclic fused pyrazole derivatives for the treatment of RSV
    Patent number: 10906899
    Abstract: Disclosed herein are compounds and compositions for treating or inhibiting RSV and related members of the pneumovirus and paramyxovirus families such as human metapneumovirus, mumps virus, human parainfluenzaviruses, and Nipah and hendra virus, and methods of treatment or prevention thereof.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: February 2, 2021
    Assignee: GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Richard K. Plemper, Eddy Lee, John Vernachio, Elyse Bourque
  • CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME
    Publication number: 20200207865
    Abstract: Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
    Type: Application
    Filed: July 26, 2019
    Publication date: July 2, 2020
    Inventors: Geoffrey WINTERS, James RICH, Graham GARNETT, Alexander MANDEL, Tom HSIEH, Elyse BOURQUE, Stuart BARNSCHER
  • GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
    Publication number: 20200048266
    Abstract: The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.
    Type: Application
    Filed: August 15, 2019
    Publication date: February 13, 2020
    Inventors: Elyse BOURQUE, Mario CABRERA-SALAZAR, Cassandra CELATKA, Seng CHENG, Mary A. CROMWELL, Andrew GOOD, Bradford HIRTH, Katherine JANCSICS, John P. LEONARD, Lingyun LI, James LILLIE, Hanlan LIU, Elina MAKINO, John MARSHALL, Paul MASON, Markus METZ, Fazeela MORSHED, Thomas O'SHEA, Ronald SCHEULE, Renato SKERLJ, Bing WANG, Yibin XIANG, Zhong ZHAO
  • BICYCLIC FUSED PYRAZOLE DERIVATIVES FOR THE TREATMENT OF RSV
    Publication number: 20190144441
    Abstract: Disclosed herein are compounds and compositions for treating or inhibiting RSV and related members of the pneumovirus and paramyxovirus families such as human metapneumovirus, mumps virus, human parainfluenzaviruses, and Nipah and hendra virus, and methods of treatment or prevention thereof.
    Type: Application
    Filed: May 10, 2017
    Publication date: May 16, 2019
    Inventors: Richard K. PLEMPER, Eddy LEE, John VERNACHIO, Elyse BOURQUE