Patents by Inventor Emad E. Hassan

Emad E. Hassan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Controlled release of drugs delivered by sublingual or buccal administration
    Patent number: 5624677
    Abstract: A composition providing a relatively slow release of water-soluble drugs, such as apomorphine, for delivery via the sublingual or buccal routes.
    Type: Grant
    Filed: June 13, 1995
    Date of Patent: April 29, 1997
    Assignee: Pentech Pharmaceuticals, Inc.
    Inventors: Ragab El-Rashidy, Bruce Ronsen, Emad E. Hassan
  • Receptor-mediated delivery system
    Patent number: 5129877
    Abstract: A delivery system for biologically active materials consisting of polysaccharide or polypeptide microspheres which bind to glycosaminoglycan receptors on cell surfaces. The delivery system can be used to localize drugs by both biochemical and physical means. In one embodiment, microspheres prepared from the polysaccharide chitosan are bound to anionic polysaccharides similar to the glycosaminoglycan receptors found on the surface of capillary endothelial cells. The microspheres were formulated to have a controlled cationic character, and had a mean diameter of 0.70 u and a magnetite content of 16% w/w. Binding to a model polysaccharide, heparin, was demonstrated in vitro. Binding to cultured cerebral capillary endothelial cells was also demonstrated.
    Type: Grant
    Filed: September 14, 1990
    Date of Patent: July 14, 1992
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: James M. Gallo, Emad E. Hassan