Patents by Inventor Emanuela Keller

Emanuela Keller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device and method for measuring blood flow in an organ
    Patent number: 7529576
    Abstract: A device has a source for emitting near infrared radiation into cerebral tissue, a sensor for detecting radiation exiting from the tissue, and an evaluation unit which detects the exiting radiation as an input signal having pulsatile and non-pulsatile components and is programmed to determine the concentration of an injected indicator in the tissue from the non-pulsatile signal component, iteratively determine an inflow function characterizing cerebral blood flow by varying a mean transit time until reaching a stop criterion, determine indicator concentration relative to cerebral blood volume from the inflow function and the pulsatile signal component, calculate cerebral blood volume by dividing indicator concentration in the tissue by indicator concentration relative to cerebral blood volume, calculate cerebral blood flow by dividing the cerebral blood volume by the mean transit time when the stop criterion has been reached, and scale the inflow function using values determined from the pulsatile signal comp
    Type: Grant
    Filed: April 1, 2004
    Date of Patent: May 5, 2009
    Assignees: Universitat Zürich, ETH Zürich
    Inventors: Emanuela Keller, Andreas Nadler, Peter Niederer
  • Device for measuring the blood flow in an organ
    Publication number: 20040249275
    Abstract: A device has a source for emitting near infrared radiation into cerebral tissue, a sensor for detecting radiation exiting from the tissue, and an evaluation unit which detects the exiting radiation as an input signal having pulsatile and non-pulsatile components and is programmed to determine the concentration of an injected indicator in the tissue from the non-pulsatile signal component, iteratively determine an inflow function characterizing cerebral blood flow by varying a mean transit time until reaching a stop criterion, determine indicator concentration relative to cerebral blood volume from the inflow function and the pulsatile signal component, calculate cerebral blood volume by dividing indicator concentration in the tissue by indicator concentration relative to cerebral blood volume, calculate cerebral blood flow by dividing the cerebral blood volume by the mean transit time when the stop criterion has been reached, and scale the inflow function using values determined from the pulsatile signal comp
    Type: Application
    Filed: April 1, 2004
    Publication date: December 9, 2004
    Inventors: Emanuela Keller, Andreas Nadler, Peter Niederer