Patents by Inventor Emeline Maillet

Emeline Maillet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR REDUCING TOLERANCE TO OPIOID ANALGESICS USING IBOGAINE AND DERIVATIVES THEREOF
    Publication number: 20240024336
    Abstract: A method for modulating tolerance to an opioid analgesic in a patient undergoing opioid analgesic therapy, the method comprising interrupting or administering concurrently with said opioid analgesic therapy an amount of ibogaine, ibogaine derivative, or pharmaceutically acceptable salt and/or solvate thereof.
    Type: Application
    Filed: September 13, 2023
    Publication date: January 25, 2024
    Inventors: Emeline MAILLET, Lawrence FRIEDHOFF
  • METHODS FOR ACUTE AND LONG-TERM TREATMENT OF ALCOHOL DEPENDENCE USING IBOGAINE AND DERIVATIVES THEREOF
    Publication number: 20230346795
    Abstract: This invention is directed to a method of treating alcohol dependence, including acute and post-acute withdrawal symptoms, comprising treating an alcohol dependent patient with ibogaine, ibogaine derivative, or pharmaceutically acceptable salt and/or solvate thereof at a dosage that provides an average serum concentration of about 50 ng/mL to about 850 ng/mL under conditions where the QT interval prolongation does not exceed about 50 milliseconds.
    Type: Application
    Filed: May 9, 2023
    Publication date: November 2, 2023
    Inventors: Emeline MAILLET, Lawrence FRIEDHOFF
  • METHODS AND COMPOSITIONS FOR POTENTIATING THE ACTION OF OPIOID ANALGESICS USING IBOGA ALKALOIDS
    Publication number: 20220193088
    Abstract: Methods and compositions for potentiating the effect of an opioid analgesic in a patient undergoing or planning to undergo opioid analgesic therapy using a potentiating amount of iboga alkaloid or pharmaceutically acceptable salt and/or solvate thereof that does not prolong the patient's QT interval by more than about 50 milliseconds.
    Type: Application
    Filed: January 20, 2022
    Publication date: June 23, 2022
    Inventors: Holger WEIS, Emeline MAILLET
  • Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids
    Patent number: 11260059
    Abstract: Methods and compositions for potentiating the effect of an opioid analgesic in a patient undergoing or planning to undergo opioid analgesic therapy using a potentiating amount of iboga alkaloid or pharmaceutically acceptable salt and/or solvate thereof that does not prolong the patient's QT interval by more than about 50 milliseconds.
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: March 1, 2022
    Assignee: DEMERX, INC.
    Inventors: Holger Weis, Emeline Maillet
  • Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids
    Patent number: 11197866
    Abstract: Methods and compositions for potentiating the effect of an opioid analgesic in a patient undergoing or planning to undergo opioid analgesic therapy using a potentiating amount of iboga alkaloid or pharmaceutically acceptable salt and/or solvate thereof that does not prolong the patient's QT interval by more than about 50 milliseconds.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: December 14, 2021
    Assignee: DEMERX, INC.
    Inventors: Holger Weis, Emeline Maillet
  • METHODS AND COMPOSITIONS FOR POTENTIATING THE ACTION OF OPIOID ANALGESICS USING IBOGA ALKALOIDS
    Publication number: 20210299139
    Abstract: Methods and compositions for potentiating the effect of an opioid analgesic in a patient undergoing or planning to undergo opioid analgesic therapy using a potentiating amount of iboga alkaloid or pharmaceutically acceptable salt and/or solvate thereof that does not prolong the patient's QT interval by more than about 50 milliseconds.
    Type: Application
    Filed: June 8, 2021
    Publication date: September 30, 2021
    Inventors: Holger WEIS, Emeline MAILLET
  • METHODS AND COMPOSITIONS FOR REDUCING TOLERANCE TO OPIOID ANALGESICS USING IBOGAINE AND DERIVATIVES THEREOF
    Publication number: 20210290634
    Abstract: A method for modulating tolerance to an opioid analgesic in a patient undergoing opioid analgesic therapy, the method comprising interrupting or administering concurrently with said opioid analgesic therapy an amount of ibogaine, ibogaine derivative, or pharmaceutically acceptable salt and/or solvate thereof.
    Type: Application
    Filed: June 4, 2021
    Publication date: September 23, 2021
    Inventors: Emeline MAILLET, Lawrence FRIEDHOFF
  • Methods and compositions for ibogaine treatment of impulse control disorder, anxiety-related disorders, violence and/or anger, or regulating food intake
    Patent number: 11077118
    Abstract: This invention provides a method for treating anxiety-related disorder or impulse control disorder, regulating food intake, attenuating food cravings, or treating anger and/or violence and disorders associated therewith in a patient, comprising administering to the patient in need thereof a therapeutically effective amount of ibogaine, ibogaine derivative, or a pharmaceutically acceptable salt and/or solvate thereof.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: August 3, 2021
    Assignee: DEMERX, INC.
    Inventor: Emeline Maillet
  • METHODS FOR ACUTE AND LONG-TERM TREATMENT OF ALCOHOL DEPENDENCE USING IBOGAINE AND DERIVATIVES THEREOF
    Publication number: 20210145845
    Abstract: This invention is directed to a method of treating alcohol dependence, including acute and post-acute withdrawal symptoms, comprising treating an alcohol dependent patient with ibogaine, ibogaine derivative, or pharmaceutically acceptable salt and/or solvate thereof at a dosage that provides an average serum concentration of about 50 ng/mL to about 850 ng/mL under conditions where the QT interval prolongation does not exceed about 50 milliseconds.
    Type: Application
    Filed: January 28, 2021
    Publication date: May 20, 2021
    Inventors: Emeline MAILLET, Lawrence FRIEDHOFF
  • METHODS AND COMPOSITIONS FOR POTENTIATING THE ACTION OF OPIOID ANALGESICS USING IBOGA ALKALOIDS
    Publication number: 20200352956
    Abstract: Methods and compositions for potentiating the effect of an opioid analgesic in a patient undergoing or planning to undergo opioid analgesic therapy using a potentiating amount of iboga alkaloid or pharmaceutically acceptable salt and/or solvate thereof that does not prolong the patient's QT interval by more than about 50 milliseconds.
    Type: Application
    Filed: May 22, 2020
    Publication date: November 12, 2020
    Inventors: Holger Weis, Emeline Maillet
  • Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids
    Patent number: 10660900
    Abstract: Methods and compositions for potentiating the effect of an opioid analgesic in a patient undergoing or planning to undergo opioid analgesic therapy using a potentiating amount of iboga alkaloid or pharmaceutically acceptable salt and/or solvate thereof that does not prolong the patient's QT interval by more than about 50 milliseconds.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: May 26, 2020
    Inventors: Holger Weis, Emeline Maillet
  • METHODS AND COMPOSITIONS FOR IBOGAINE TREATMENT OF IMPULSE CONTROL DISORDER, ANXIETY-RELATED DISORDERS, VIOLENCE AND/OR ANGER, OR REGULATING FOOD INTAKE
    Publication number: 20200093833
    Abstract: This invention provides a method for treating anxiety-related disorder or impulse control disorder, regulating food intake, attenuating food cravings, or treating anger and/or violence and disorders associated therewith in a patient, comprising administering to the patient in need thereof a therapeutically effective amount of ibogaine, ibogaine derivative, or a pharmaceutically acceptable salt and/or solvate thereof.
    Type: Application
    Filed: March 9, 2017
    Publication date: March 26, 2020
    Applicant: DemeRX, Inc.
    Inventor: Emeline Maillet
  • METHODS FOR ACUTE AND LONG-TERM TREATMENT OF ALCOHOL DEPENDENCE USING IBOGAINE AND DERIVATIVES THEREOF
    Publication number: 20200085836
    Abstract: This invention is directed to a method of treating alcohol dependence, including acute and post-acute withdrawal symptoms, comprising treating an alcohol dependent patient with ibogaine, ibogaine derivative, or pharmaceutically acceptable salt and/or solvate thereof at a dosage that provides an average serum concentration of about 50 ng/mL to about 850 ng/mL under conditions where the QT interval prolongation does not exceed about 50 milliseconds.
    Type: Application
    Filed: October 23, 2017
    Publication date: March 19, 2020
    Applicant: DemeRx, Inc.
    Inventors: Emeline Maillet, Lawrence Friedhoff
  • LOW DOSE NORIBOGAINE FOR TREATING NICOTINE ADDICTION AND PREVENTING RELAPSE OF NICOTINE USE
    Publication number: 20170368074
    Abstract: This invention provides methods and compositions for treating nicotine addiction or treating or preventing nicotine cravings in a subject. The method comprises administering to the patient in need thereof a therapeutically effective amount of noribogaine, noribogaine derivative, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 6, 2017
    Publication date: December 28, 2017
    Applicant: DemeRx, Inc.
    Inventors: Emeline Maillet, Lawrence Friedhoff
  • Low dose noribogaine for treating nicotine addiction and preventing relapse of nicotine use
    Patent number: 9561232
    Abstract: This invention provides methods and compositions for treating nicotine addiction or treating or preventing nicotine cravings in a subject. The method comprises administering to the patient in need thereof a therapeutically effective amount of noribogaine, noribogaine derivative, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: February 7, 2017
    Assignee: DEMERX, INC.
    Inventors: Emeline Maillet, Lawrence Friedhoff
  • METHODS AND COMPOSTIONS FOR POTENTIATING THE ACTION OF OPIOID ANALGESICS USING IBOGA ALKALOIDS
    Publication number: 20160220579
    Abstract: Methods and compositions for potentiating the effect of an opioid analgesic in a patient undergoing or planning to undergo opioid analgesic therapy using a potentiating amount of iboga alkaloid or pharmaceutically acceptable salt and/or solvate thereof that does not prolong the patient's QT interval by more than about 50 milliseconds.
    Type: Application
    Filed: April 7, 2016
    Publication date: August 4, 2016
    Inventors: Holger Weis, Emeline Maillet
  • METHODS AND COMPOSITIONS FOR TREATING IMPULSE CONTROL DISORDER, ANXIETY-RELATED DISORDERS, VIOLENCE AND/OR ANGER, OR REGULATING FOOD INTAKE
    Publication number: 20160038505
    Abstract: This invention provides a method for treating anxiety-related disorder or impulse control disorder, regulating food intake, attenuating food cravings, or treating anger and/or violence and disorders associated therewith in a patient, comprising administering to the patient in need thereof a therapeutically effective amount of noribogaine, noribogaine derivative, or a pharmaceutically acceptable salt and/or solvate thereof.
    Type: Application
    Filed: February 17, 2015
    Publication date: February 11, 2016
    Inventors: Emeline Maillet, Holger Weis
  • METHODS FOR ACUTE AND LONG-TERM TREATMENT OF ALCOHOL DEPENDENCE USING IBOGAINE
    Publication number: 20150258110
    Abstract: This invention is directed to a method of treating alcohol dependence, including acute and post-acute withdrawal symptoms, comprising treating an alcohol dependent patient with ibogaine, ibogaine derivative, or pharmaceutically acceptable salt and/or solvate thereof at a dosage that provides an average serum concentration of about 50 ng/mL to about 850 ng/mL under conditions where the QT interval prolongation does not exceed about 50 milliseconds.
    Type: Application
    Filed: March 2, 2015
    Publication date: September 17, 2015
    Applicant: DEMERX, INC.
    Inventors: Emeline Maillet, Lawrence Friedhoff
  • METHODS AND COMPOSITIONS FOR REDUCING TOLERANCE TO OPIOID ANALGESICS USING IBOGAINE AND DERIVATIVES THEREOF
    Publication number: 20150258111
    Abstract: A method for modulating tolerance to an opioid analgesic in a patient undergoing opioid analgesic therapy, the method comprising interrupting or administering concurrently with said opioid analgesic therapy an amount of ibogaine, ibogaine derivative, or pharmaceutically acceptable salt and/or solvate thereof.
    Type: Application
    Filed: March 2, 2015
    Publication date: September 17, 2015
    Inventors: Emeline Maillet, Lawrence Friedhoff
  • LOW DOSE ADMINISTRATION OF IBOGAINE FOR TREATING NICOTINE ADDICTION AND PREVENTING RELAPSE OF NICOTINE USE
    Publication number: 20150258109
    Abstract: This invention relates generally to methods and compositions for the treatment of nicotine addiction by administering ibogaine, an ibogaine derivative, or a pharmaceutically acceptable salt and/or solvate thereof to a patient in low doses. This invention further relates generally to methods and compositions for the treatment or prevention of relapse of nicotine use by administering ibogaine, an ibogaine derivative, or a pharmaceutically acceptable salt and/or solvate thereof to a patient in low doses.
    Type: Application
    Filed: March 2, 2015
    Publication date: September 17, 2015
    Applicant: DEMERX, INC.
    Inventors: Emeline Maillet, Lawrence Friedhoff