Patents by Inventor Emil Karapetian

Emil Karapetian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210282923
    Abstract: Anchor devices and methods used to secure a prosthetic valve to a native valve annulus are described. The anchor device can be a separate expandable element from the prosthetic valve that is first advanced to the annulus and deployed, after which an expandable prosthetic valve is advanced to within the annulus and deployed. The combination of the two elements can apply a clamping force to the valve leaflets which holds the prosthetic valve in place. The anchor device can have a lower or ventricular portion and an upper or atrial portion. The anchor device can include one or more leaflet clamping portions. One, two, or more upstanding vertical posts between the clamping portions can extend upward at the valve commissures and support the upper portion, which can include one or more structures for leak prevention.
    Type: Application
    Filed: May 28, 2021
    Publication date: September 16, 2021
    Inventors: Dustin P. Armer, Sean Chow, Jenny Nguyen, Emil Karapetian, Tri D. Tran
  • Publication number: 20210267585
    Abstract: A tissue anchor includes a driver head associated with a proximal portion of the tissue anchor, a pointed tip portion associated with a distal portion of the tissue anchor, a tissue-engagement portion disposed between the driver head and the pointed tip portion, and a cover configured to cover at least a portion of the tissue-engagement portion.
    Type: Application
    Filed: May 17, 2021
    Publication date: September 2, 2021
    Inventor: Emil Karapetian
  • Patent number: 11026673
    Abstract: A tissue anchor includes a driver head associated with a proximal portion of the tissue anchor, a pointed tip portion associated with a distal portion of the tissue anchor, a tissue-engagement portion disposed between the driver head and the pointed tip portion, and a cover configured to cover at least a portion of the tissue-engagement portion.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: June 8, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventor: Emil Karapetian
  • Patent number: 11026781
    Abstract: Anchor devices and methods can be used to secure a prosthetic valve to a native valve annulus. The anchor device can be a separate expandable element from the prosthetic valve that is first advanced to the annulus and deployed, after which an expandable prosthetic valve is advanced to within the annulus and deployed. The combination of the two elements can apply a clamping force to the valve leaflets which holds the prosthetic valve in place. The anchor device can have a lower or ventricular portion and an upper or atrial portion. The anchor device can include one or more leaflet clamping portions. One, two, or more upstanding vertical posts between the clamping portions can extend upward at the valve commissures and support the upper portion, which can include one or more structures for leak prevention.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: June 8, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Dustin P. Armer, Sean Chow, Jenny Nguyen, Emil Karapetian, Tri D. Tran
  • Publication number: 20200405483
    Abstract: An improved holder and storage system for a tissue-type prosthetic mitral heart valve that constricts the commissure posts of the valve and prevents suture looping. A rod axially movable relative to the holder tensions lengths of attachment sutures that extend between the commissure post tips to create a tent and flex the tips inward, thus helping to prevent looping of any of an array of pre-implanted sutures around the leading tips during delivery of the valve. The holder has a safety mechanism that prevents valve delivery before the rod is deployed. One embodiment automatically deploys the rod upon opening a storage jar. One embodiment permits a delivery handle to directly deploy the rod, while another uses a separate worm screw and coupling. A holder clip that attaches to a packaging sleeve may be formed of flexible members meshed together from which the heart valve and holder are easily pulled free to eliminate a step of decoupling the clip from the sleeve.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Inventors: Michael C. Murad, Emil Karapetian, Wesley V. Adzich
  • Patent number: 10772725
    Abstract: An improved holder and storage system for a tissue-type prosthetic mitral heart valve that constricts the commissure posts of the valve and prevents suture looping. A rod axially movable relative to the holder tensions lengths of attachment sutures that extend between the commissure post tips to create a tent and flex the tips inward, thus helping to prevent looping of any of an array of pre-implanted sutures around the leading tips during delivery of the valve. The holder has a safety mechanism that prevents valve delivery before the rod is deployed. One embodiment automatically deploys the rod upon opening a storage jar. One embodiment permits a delivery handle to directly deploy the rod, while another uses a separate worm screw and coupling. A holder clip that attaches to a packaging sleeve may be formed of flexible members meshed together from which the heart valve and holder are easily pulled free to eliminate a step of decoupling the clip from the sleeve.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: September 15, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Michael C. Murad, Emil Karapetian, Wesley V. Adzich
  • Publication number: 20200138568
    Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Inventors: Emil Karapetian, Maria Charles Vija Stanislaus, Gregory Bak-Boychuk, Christopher J. Olson, Cristobal R. Hernandez, William C. Brunnett, Netanel Benichou, Lauren R. Freschauf, Alexander J. Siegel, Stanton J. Rowe, Alison S. Curtis
  • Publication number: 20200085573
    Abstract: Anchor devices and methods used to secure a prosthetic valve to a native valve annulus are described. The anchor device can be a separate expandable element from the prosthetic valve that is first advanced to the annulus and deployed, after which an expandable prosthetic valve is advanced to within the annulus and deployed. The combination of the two elements can apply a clamping force to the valve leaflets which holds the prosthetic valve in place. The anchor device can have a lower or ventricular portion and an upper or atrial portion. The anchor device can include one or more leaflet clamping portions. One, two, or more upstanding vertical posts between the clamping portions can extend upward at the valve commissures and support the upper portion, which can include one or more structures for leak prevention.
    Type: Application
    Filed: November 21, 2019
    Publication date: March 19, 2020
    Inventors: Dustin P. Armer, Sean Chow, Jenny Nguyen, Emil Karapetian, Tri D. Tran
  • Publication number: 20200054335
    Abstract: Valve repair systems and clips for attachment to one or more leaflets of a heart valve. The clip can include an elongated member configured to be positioned between two leaflets of the heart valve. The elongated member can have a first portion and a second portion that extends from the first portion. A width of the second portion can be greater than the width of the first portion. A pair of arms can be coupled to the first portion and extend toward the second portion. The pair of arms can extend radially away from the elongated member as the pair of arms extend away from the first portion toward the second portion when the arms are in an open position. And the pair of arms can be moveable from the open position to a closed position to pinch each leaflet between one of the arms and the elongated member.
    Type: Application
    Filed: October 24, 2019
    Publication date: February 20, 2020
    Inventors: Cristobal R. Hernandez, Gregory Bak-Boychuk, Emil Karapetian
  • Patent number: 10524792
    Abstract: A leaflet clip has an elongated member including a proximal end portion and a distal end portion, and first and second clipping arms movable between an open position and a closed position. The clipping arms include respective proximal end portions coupled to the proximal end portion of the elongated member, and respective distal end portions extending distally and radially outward relative to the elongated member. The leaflet clip further includes a tubular member coaxially disposed about the elongated member. Axial motion of the tubular member with respect to the elongated member or axial motion of the elongated member with respect to the tubular member causes corresponding movement of the clipping arms between the open and closed positions.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: January 7, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Cristobal R. Hernandez, Gregory Bak-Boychuk, Emil Karapetian
  • Patent number: 10517726
    Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion, wherein the prosthetic device is movable between a compressed configuration, in which the spacer body portion is radially compressed and is axially spaced relative to the anchor portion, and an expanded configuration, in which the spacer body portion expands radially outwardly relative to the compressed configuration and overlaps at least a portion of the anchor portion.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: December 31, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Mark Chau, David M. Taylor, Alexander J. Siegel, Christopher J. Olson, Sergio Delgado, Alexander H. Cooper, Lauren R. Freschauf, Asher L. Metchik, Matthew T. Winston, Cristobal R. Hernandez, Emil Karapetian, Bao Khuu, Eric Dixon
  • Patent number: 10507106
    Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts. The support frame further comprises one or more leaflet-engaging mechanisms configured to engage leaflets of the heart valve. The support frame can be radially expandable and collapsible.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: December 17, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Emil Karapetian, Maria Charles Vija Stanislaus, Gregory Bak-Boychuk, Christopher J. Olson, Cristobal R. Hernandez, William C. Brunnett, Netanel Benichou, Lauren R. Freschauf, Alexander J. Siegel
  • Publication number: 20190365539
    Abstract: A cardiac tissue repositioning device comprises a first attachment member configured to be anchored to a first portion of cardiac tissue. The device further comprises a second attachment member configured to be anchored to a second portion of cardiac tissue. The device further comprises an adjustable body configured to be moveable between multiple positions and a locking mechanism configured to control movement of the adjustable body between the multiple positions.
    Type: Application
    Filed: May 17, 2019
    Publication date: December 5, 2019
    Inventors: Glen T. Rabito, Alison S. Curtis, Emil Karapetian
  • Publication number: 20190365368
    Abstract: An anchoring system comprises a first anchoring device comprising a first attachment mechanism and a plugging device and a second anchoring device comprising a second attachment mechanism, each of the first anchoring device and the second anchoring device being configured to enter a tissue wall at a proximal side of the tissue wall, the first anchoring device being configured to exit the tissue wall through a first hole on a distal side of the tissue wall, the second anchoring device being configured to exit the tissue wall at a second hole on the distal side of the tissue wall, the first attachment mechanism configured to attach to the second attachment mechanism outside of the distal side of the tissue wall, and the plugging device configured to cover the first hole and fit between at least a portion of the first anchoring device and the distal side of the tissue wall.
    Type: Application
    Filed: May 21, 2019
    Publication date: December 5, 2019
    Inventor: Emil Karapetian
  • Publication number: 20190343624
    Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be configured to extend radially outwardly as the spacer body extends away from the distal end toward the proximal end. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.
    Type: Application
    Filed: July 25, 2019
    Publication date: November 14, 2019
    Applicant: Edwards Lifesciences Corporation
    Inventors: Mark Chau, David M. Taylor, Alexander J. Siegel, Christopher J. Olson, Sergio Delgado, Alexander H. Cooper, Lauren R. Freschauf, Asher L. Metchik, Matthew T. Winston, Cristobal R. Hernandez, Emil Karapetian, Bao Khuu, Eric Robert Dixon
  • Publication number: 20190343506
    Abstract: A tissue anchor includes a driver head associated with a proximal portion of the tissue anchor, a pointed tip portion associated with a distal portion of the tissue anchor, a tissue-engagement portion disposed between the driver head and the pointed tip portion, and a cover configured to cover at least a portion of the tissue-engagement portion.
    Type: Application
    Filed: March 28, 2019
    Publication date: November 14, 2019
    Inventor: Emil Karapetian
  • Publication number: 20190343623
    Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be made from braided, self-expandable metallic thread. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.
    Type: Application
    Filed: July 25, 2019
    Publication date: November 14, 2019
    Inventors: Mark Chau, David M. Taylor, Alexander J. Siegel, Christopher J. Olson, Sergio Delgado, Alexander H. Cooper, Lauren R. Freschauf, Asher L. Metchik, Matthew T. Winston, Cristobal R. Hernandez, Emil Karapetian, Bao Khuu, Eric Robert Dixon
  • Patent number: 10463364
    Abstract: In repairing soft tissue with a bone anchoring instrument (such as reattaching a tendon of a torn rotator cuff), the bone anchoring instrument may be used to anchor the soft tissue to a region of bone. The anchors inserted into the underlying bone may have one or more lengths of suture or wire attached thereto which may be tensioned independently of one another to affix the soft tissue to the bone by having a selector mechanism selectively engage and disengage ratcheted tensioning wheels from one another. Suture loading mechanisms may be employed for passing suture lengths into and/or through the anchors prior to deployment into the bone where such mechanisms may employ suture snares which are configured to reconfigure from an expanded shape through which suture lengths may be easily passed to a low-profile shape which secures the suture lengths within the snare.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: November 5, 2019
    Assignee: ArthroCare Corporation
    Inventors: George W. White, David Gregoire, David Aldridge, Edward E. Dolendo, Emil Karapetian, Norman S. Gordon, Tri Nguyen
  • Publication number: 20190328512
    Abstract: Pinch devices and access systems that can be used to secure a prosthetic heart valve to a heart valve annulus and to treat valvular insufficiency. A pinch device can be a separate expandable element from the prosthetic heart valve that is first advanced to the annulus and deployed, after which an expandable prosthetic heart valve can be advanced to within the annulus and deployed. The two elements can clamp/pinch the heart valve leaflets to hold the prosthetic heart valve in place. The pinch device can have a flexible, expandable annular frame. A combined delivery system can deliver the pinch device and prosthetic heart valve with just a single access point and aid more accurate coaxial deployment. The pinch device can be mounted near distal end of an access sheath, and a catheter for delivering the prosthetic heart valve can be passed through a lumen of the same access sheath.
    Type: Application
    Filed: July 11, 2019
    Publication date: October 31, 2019
    Inventors: Hamid Rafi, Russell T. Joseph, Robert Bowes, Uy D. Trinh, Emil Karapetian, Gregory Bak-Boychuk
  • Publication number: 20190269509
    Abstract: A device for crimping a radially expandable and collapsible prosthetic valve comprises a crimping loop having a first end portion, a second end portion, and a loop portion extending between the first and second end portions and defining an opening configured to receive the prosthetic valve. The crimping loop is movable between a first state in which the opening has a first diameter and a second state in which the opening has a second diameter smaller than the first diameter such that when the prosthetic valve is positioned within the loop portion, movement of the crimping loop from the first state to the second state is effective to reduce a diameter of the prosthetic valve. A method for crimping a prosthetic valve comprises reducing a diameter of an opening of a crimping loop, thereby radially compressing an at least partially expanded prosthetic valve disposed within the opening.
    Type: Application
    Filed: May 17, 2019
    Publication date: September 5, 2019
    Inventors: David Maimon, Ron Sharoni, Tamir S. Levi, Emil Karapetian, Tri D. Tran, Tung Le