Patents by Inventor Emil Samara

Emil Samara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETED DELIVERY OF THERAPEUTIC AGENTS
    Publication number: 20230285572
    Abstract: Provided herein are methods and compositions using a target moiety linked to an active agent, in particular an antimicrobial agent. Such methods and compositions are useful in treating, e.g., microbial infections, such as antibiotic-resistant bacterial infections. Provided herein are methods and compositions using a target moiety linked to an active agent, in particular an antimicrobial agent. Such methods and compositions are useful in treating, e.g., microbial infections, such as antibiotic-resistant bacterial infections.
    Type: Application
    Filed: August 3, 2021
    Publication date: September 14, 2023
    Inventors: Emil SAMARA, Tomasz GLINKA, Wolf-Nicolas FISCHER, Bernd JANDELEIT
  • Methods of treatment of endobronchial infections
    Patent number: 8664187
    Abstract: The present invention provides methods for the treatment of an endobronchial infection in a patient by administering to the endobronchial system of the patient a dry powder aerosol composition comprising from 90 to 130 mg of an aminoglycoside antibiotic one to three times a day for a first treatment period of 20 to 36 days.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: March 4, 2014
    Assignee: Novartis AG
    Inventors: Peter Challoner, Carlos Rodriguez, Emil Samara, Thomas E Tarara, John D Lord
  • METHODS OF TREATMENT OF ENDOBRONCHIAL INFECTIONS
    Publication number: 20120148641
    Abstract: The present invention provides methods for the treatment of an endobronchial infection in a patient by administering to the endobronchial system of the patient a dry powder aerosol composition comprising from 90 to 130 mg of an aminoglycoside antibiotic one to three times a day for a first treatment period of 20 to 36 days.
    Type: Application
    Filed: February 24, 2012
    Publication date: June 14, 2012
    Inventors: Peter Challoner, Carlos Rodriguez, Emil Samara, Thomas E. Tarara, John D. Lord
  • METHODS OF TREATMENT OF ENDOBRONCHIAL INFECTIONS
    Publication number: 20110097412
    Abstract: The present invention provides methods for the treatment of an endobronchial infection in a patient by administering to the endobronchial system of the patient a dry powder aerosol composition comprising from 90 to 130 mg of an aminoglycoside antibiotic one to three times a day for a first treatment period of 20 to 36 days.
    Type: Application
    Filed: January 4, 2011
    Publication date: April 28, 2011
    Inventors: Peter Challoner, Carlos Rodriguez, Emil Samara, Thomas E. Tarara, John D. Lord
  • Methods of treating cancer and related methods
    Patent number: 7838527
    Abstract: Methods of treating cancer using 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one are provided. In particular, the methods are effective for the treatment of solid tumors or leukemias, including prostate, colorectal, breast, multiple myeloma, pancreatic, small cell carcinoma, acute myelogenous leukemia, chronic myelogenous leukemia, or myelo-proliferative disease. Further provided are methods of measuring the amount of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one and determining a metabolic profile therefore.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: November 23, 2010
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Alison Hannah, Eric Harwood, Peter Haroldsen, Carla Heise, Timothy Machajewski, Emil Samara, Xiao Shang, Jayesh Vora, Shuguang Zhu
  • Methods of Treatment of Endobronchial Infections
    Publication number: 20080214481
    Abstract: The present invention provides methods for the treatment of an endobronchial infection in a patient by administering to the endobronchial system of the patient a dry powder aerosol composition comprising from 90 to 130 mg of an aminoglycoside antibiotic one to three times a day for a first treatment period of 20 to 36 days.
    Type: Application
    Filed: June 20, 2005
    Publication date: September 4, 2008
    Applicants: NOVARTIS VACCINES AND DIAGNOSTICS, INC., NEKTAR THERAPEUTICS
    Inventors: Peter Challoner, Carlos Rodriguez, Emil Samara, Thomas E. Tarara, John D. Lord
  • Methods of treating cancer and related methods
    Publication number: 20040220196
    Abstract: Methods of treating cancer using 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1 -yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one are provided. In particular, the methods are effective for the treatment of solid tumors or leukemias, including prostate, colorectal, breast, multiple myeloma, pancreatic, small cell carcinoma, acute myelogenous leukemia, chronic myelogenous leukemia, or myelo-proliferative disease. Further provided are methods of measuring the amount of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1 -yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one and determining a metabolic profile therefore.
    Type: Application
    Filed: November 12, 2003
    Publication date: November 4, 2004
    Applicant: Chiron Corporation
    Inventors: Alison Hannah, Eric Harwood, Peter Haroldsen, Carla Heise, Timothy Machajewski, Emil Samara, Xiao Shang, Jayesh Vora, Shuguang Zhu