Patents by Inventor Emile Cavoy

Emile Cavoy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of Levetiracetam and analogues
    Patent number: 7563912
    Abstract: The present invention relates to an improved process for the preparation of (S)-(?)-?-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R2 is C?2#191 -C?4#191 alkyl, C?2#191-C?4#191 alkenyl or C?2#191-C?4#191 alkynyl, optionally substituted by one or more halogen, and their preparation processes.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: July 21, 2009
    Assignee: UCB Pharma, S.A.
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • Piperazine derivatives and their use as synthesis intermediates
    Patent number: 7381821
    Abstract: The present invention relates to new enantiomerically pure piperazine derivatives of formula (I) wherein Y represents hydroxy or a leaving group and n is 1, 2, 3, 4 or 5, and to their use as synthesis intermediates, especially for the preparation of pharmaceutically active compounds
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: June 3, 2008
    Assignee: UCB, S.A.
    Inventors: Célal Ates, Emile Cavoy, Didier Bouvy
  • Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues
    Publication number: 20070142647
    Abstract: The present invention relates to an improved process for the preparation of (S)-(-)-?-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R2 is C2-C4 alkyl, C2-C4 alkenyl or C2-C4 alkynyl, optionally substituted by one or more halogen, and their preparation processes.
    Type: Application
    Filed: October 2, 2006
    Publication date: June 21, 2007
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • Process for preparing (S) and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
    Patent number: 7199241
    Abstract: The present invention relates to a process for preparing (S)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide by separation of a racemic mixture using multiple column chromatography.
    Type: Grant
    Filed: October 17, 2005
    Date of Patent: April 3, 2007
    Assignee: UCB, S.A.
    Inventors: Vincent Zimmermann, Emile Cavoy, Michel Hamende
  • Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of Levetiracetam and analogues
    Publication number: 20060258734
    Abstract: The present invention relates to an improved process for the preparation of (S)-(?)-?-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R2 is C?2#191 -C?4#191 alkyl, C?2#191-C?4#191 alkenyl or C?2#191-C?4#191 alkynyl, optionally substituted by one or more halogen, and their preparation processes.
    Type: Application
    Filed: July 18, 2006
    Publication date: November 16, 2006
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues
    Patent number: 7122682
    Abstract: The present invention relates to an improved process for the preparation of (S)-(?)-?-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: October 17, 2006
    Assignee: UCB, S.A.
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • Piperazine derivatives and their use as synthesis intermediates
    Publication number: 20060183903
    Abstract: The present invention relates to new enantiomerically pure piperazine derivatives of formula (I) wherein Y represents hydroxy or a leaving group and n is 1, 2, 3, 4 or 5, and to their use as synthesis intermediates, especially for the preparation of pharmaceutically active compounds.
    Type: Application
    Filed: January 20, 2004
    Publication date: August 17, 2006
    Applicant: UCB, S.A.
    Inventors: Celal Ates, Emile Cavoy, Didier Bouvy
  • Process for preparing (S) and (R)—2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
    Patent number: 6977301
    Abstract: The present invention relates to a process for preparing (S)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide by separation of a racemic mixture using multiple column chromatography.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: December 20, 2005
    Assignee: UCB, S.A.
    Inventors: Vincent Zimmerman, Emile Cavoy, Michel Hamende
  • Oxopyrrolidine compounds, preparations of said compounds and their use in the manufacturing of levetiracetam and analogues
    Publication number: 20040204476
    Abstract: The present invention relates to an improved process for the preparation of (S)-(−)-&agr;-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R2 is C?2#19 1-C?4#191 alkyl, C?2#191 -C?4#191 alkenyl or C?2#191-C?4#191 alkynyl, optionally substituted by one or more halogen, and their preparation processes.
    Type: Application
    Filed: February 10, 2004
    Publication date: October 14, 2004
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • Process for separation in a simulated moving bed of at least one component in columns that have a suitable length to diameter ratio
    Patent number: 6533940
    Abstract: The invention relates to a process for separating at least one component of a mixture in a simulated moving bed, in which each of the chromatographic columns that contains an adsorbent has a ratio of L (length) to D (diameter) of between 0.01 and 0.34, and the ratio of LTOT (length in n columns) to D (diameter) is between 0.06 and 2.3. It is possible to apply an axial dynamic pressure on each of the upper columns that exceeds the pressure drop of all of the columns.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: March 18, 2003
    Assignee: Novasep
    Inventors: Sylvie Lehoucq, Olivier Ludemann-Hombourger, Roger-Marc Nicoud, Michel Hamende, Emile Cavoy
  • Process and device for separation in a simulated moving bed of at least one component in columns that have a suitable length to diameter ratio
    Publication number: 20020011445
    Abstract: The invention relates to a process and a device for separating at least one component of a mixture in a simulated moving bed, in which each of the chromatographic columns that contains an absorbent has a ratio of L (length) to D (diameter) of between 0.01 and 0.34.
    Type: Application
    Filed: June 28, 2001
    Publication date: January 31, 2002
    Applicant: NOVASEP SAS
    Inventors: Sylvie Lehoucq, Olivier Ludemann-Hombourger, Roger-Marc Nicoud, Michel Hamende, Emile Cavoy
  • Process for preparing (s)- and (R)-.alpha.-ethyl-2-oxo-1-pyrrolidineacetamide
    Patent number: 6124473
    Abstract: The present invention relates to a process for preparing (S)- and (R)-.alpha.-ethyl-2-oxo-1-pyrrolidineacetamide and (R)-.alpha.-ethyl-2-oxo-1-pyrrolidineacetamide. According to this process, the enantiomeric resolution of the racemic mixture of .alpha.-ethyl-2-oxo-1-pyrrolidineacetamide is carried out by simulated mobile bed chromatography, using at least three columns filled with chiral stationary phase.This process makes it possible to achieve good production efficiency on the industrial scale.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: September 26, 2000
    Assignee: UCB, S.A.
    Inventors: Emile Cavoy, Michel Hamende, Michel Deleers, Jean-Pierre Canvat, Vincent Zimmermann
  • Process for the preparation of levetiracetam
    Patent number: 6107492
    Abstract: Levetiracetam is prepared by optical resolution of etiracetam by means of preparative high performance liquid chromatography or continuous simulated moving bed chromatographic system using silica gel supporting amylose tris(3,5-dimethylphenylcarbamate) as a packing material.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: August 22, 2000
    Assignees: UCB, S.A., Daicel Chemical Industries, Ltd.
    Inventors: Tooru Futagawa, Jean-Pierre Canvat, Emile Cavoy, Michel Deleers, Michel Hamende, Vincent Zimmermann