Patents by Inventor Emile Johann Velthuisen

Emile Johann Velthuisen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS USEFUL IN HIV THERAPY
    Publication number: 20240182473
    Abstract: The invention relates to compounds of Formula (I), (Ia), (II) or (IIa), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: November 14, 2023
    Publication date: June 6, 2024
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John F. MILLER, B. Narasimhulu NAIDU, Vicente SAMANO, David TEMELKOFF, Emile Johann VELTHUISEN
  • COMBINATION OF CABOTEGRAVIR AND LEVONORGESTREL
    Publication number: 20230321089
    Abstract: The present invention relates to a combination formulation of antiretroviral pharmaceutical compositions and contraceptive agents for the treatment or prevention of human immunodeficiency virus (HIV) and the prevention of pregnancy, the composition comprising an effective amount of Cabotegravir and an effective amount of a contraceptive agent. The present invention also provides a method of preventing pregnancy and treating or preventing HIV in a human by administering a therapeutically effective amount of Cabotegravir and an effective amount of a contraceptive agent to the human.
    Type: Application
    Filed: August 30, 2021
    Publication date: October 12, 2023
    Inventors: Nima AKHAVEIN, Simone ALIDORI, Emile Johann VELTHUISEN
  • COMPOUNDS USEFUL IN HIV THERAPY
    Publication number: 20230174534
    Abstract: The invention relates to a compound of the formula: salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: May 4, 2020
    Publication date: June 8, 2023
    Inventors: John F. MILLER, Emile Johann VELTHUISEN
  • COMPOUNDS USEFUL IN HIV THERAPY
    Publication number: 20220411425
    Abstract: The invention relates to a compound having the structure: or a pharmaceutically acceptable salt thereof, along with pharmaceutical compositions and therapeutic methods thereof.
    Type: Application
    Filed: June 1, 2021
    Publication date: December 29, 2022
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John F. MILLER, B. Narasimhulu NAIDU, Vicente SAMANO, David TEMELKOFF, Emile Johann VELTHUISEN
  • COMPOUNDS USEFUL IN HIV THERAPY
    Publication number: 20220298160
    Abstract: The invention relates to compounds of Formulae (I)-(II), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: August 28, 2020
    Publication date: September 22, 2022
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John MILLER, Lita S. SUWANDI, David TEMELKOFF, Emile Johann VELTHUISEN
  • 4'-ETHYNYL-2'-DEOXYADENOSINE DERIVATIVES AND THEIR USE IN HIV THERAPY
    Publication number: 20220259252
    Abstract: The invention relates to compounds of Formulae (I) and (II), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: July 30, 2020
    Publication date: August 18, 2022
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: John MILLER, Vicente SAMANO, David TEMELKOFF, Emile Johann VELTHUISEN
  • Compounds Useful in HIV Therapy
    Publication number: 20220117993
    Abstract: The invention relates to compounds of the Formula: salts thereof, pharmaceutical compositions thereof, combinations thereof, as well as therapeutic methods of treatment and prevention.
    Type: Application
    Filed: August 8, 2019
    Publication date: April 21, 2022
    Applicants: GlaxoSmithKline Intellectual Property (No. 2) Limited, VIIV Healthcare Company
    Inventors: John Franklin MILLER, David TEMELKOFF, Emile Johann VELTHUISEN, Martha Alicia DE LA ROSA, Lita SUWANDI, B. Narasimhulu NAIDU
  • Compounds Useful in HIV Therapy
    Publication number: 20210323993
    Abstract: The invention relates to compounds of Formulae (I), (Ia), (II) and (IIa), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: August 28, 2019
    Publication date: October 21, 2021
    Applicants: GlaxosmithKline Intellectual Property (No. 2) Limited, ViiV Healthcare Company
    Inventors: John MILLER, David TEMELKOFF, Emile Johann VELTHUISEN, Martha Alicia DE LA ROSA, Lisa SUWANDI
  • Medical Use
    Publication number: 20200407393
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Application
    Filed: March 6, 2019
    Publication date: December 31, 2020
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John Franklin MILLER, David TEMELKOFF, Emile Johann VELTHUISEN
  • ISOINDOLINE DERIVATIVES
    Publication number: 20200255411
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: December 1, 2016
    Publication date: August 13, 2020
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • ANTIBODY-DRUG CONJUGATES AND THERAPEUTIC METHODS USING THE SAME
    Publication number: 20190328900
    Abstract: The invention discloses an antibody-drug conjugate of Formula (I): Ab-[L-Dn]x??(I) wherein: Ab comprises a broadly neutralizing anti-HIV antibody; L comprises a linker molecule covalently bonded to said broadly neutralizing anti-HIV antibody; D comprises one or more drugs comprising an HIV therapeutic compound covalently bonded to said linker molecule L, wherein said one or more broadly neutralizing anti-HIV antibodies Ab specifically bind to an HIV envelope glycoprotein and said one or more drugs D specifically bind to an HIV envelope glycoprotein; n is selected from 1-4; and x is selected from 1-12.
    Type: Application
    Filed: June 30, 2017
    Publication date: October 31, 2019
    Inventors: Jerry JEFFREY, Jun TANG, Vincent Wing-Fai TAI, David TEMELKOFF, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • INDOLINE DERIVATIVES
    Publication number: 20190284136
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: July 17, 2017
    Publication date: September 19, 2019
    Inventors: Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • Benzoazepine derivatives
    Patent number: 10239840
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: March 26, 2019
    Assignee: VIIV HEALTHCARE UK LIMITED
    Inventors: Brian Alvin Johns, Lita S. Suwandi, Emile Johann Velthuisen, Jason Gordon Weatherhead
  • TETRAHYDROISOQUINOLINE DERIVATIVES
    Publication number: 20180334436
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: December 1, 2016
    Publication date: November 22, 2018
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • ISOINDOLINE DERIVATIVES
    Publication number: 20180334453
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: December 1, 2016
    Publication date: November 22, 2018
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • ISOINDOLINE DERIVATIVES
    Publication number: 20180327355
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: December 1, 2016
    Publication date: November 15, 2018
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • Isoindolinone derivatives useful as antiviral agents
    Patent number: 10118894
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: November 6, 2018
    Assignee: ViiV HEALTHCARE UK LIMITED
    Inventors: Brian Alvin Johns, Emile Johann Velthuisen, Jason Gordon Weatherhead
  • Isoindoline derivatives for use in the treatment of a viral infection
    Patent number: 10112899
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: October 30, 2018
    Assignee: ViiV HEALTHCARE UK LIMITED
    Inventors: Brian Alvin Johns, Emile Johann Velthuisen, Jason Gordon Weatherhead, Lita Suwandi, David Temelkoff
  • ISOINDOLINE DERIVATIVES FOR USE IN THE TREATMENT OF A VIRAL INFECTION
    Publication number: 20180244617
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: July 6, 2015
    Publication date: August 30, 2018
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD, Lita SUWANDI, David TEMELKOFF
  • BENZOAZEPINE DERIVATIVES
    Publication number: 20180179162
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: September 14, 2016
    Publication date: June 28, 2018
    Inventors: Brian Alvin JOHNS, Lita S. SUWANDI, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD