Patents by Inventor Emilia Leitäo

Emilia Leitäo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the esterification of a carbothioic acid
    Patent number: 9670246
    Abstract: A process for preparing compounds of formula [II] by esterification of the C-17 hydroxyl group of 6?,9?-difluoro-11?,17?-dihydroxy-16?-methyl-3-oxoandrosta-1,4-diene-17?-carbothioic acid, the compound of formula [I] comprises treating compound [I] with a slight excess of an acyl chloride of general formula R—COCl, where R represents —CH2CH3, —CH2CH2CH3 or —CH(CH3)2, in an inert solvent, in the presence of a tertiary amine. Preferably the process is carried out using pyridine in the presence of acetone at a temperature of from 5° C. to ?20° C.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: June 6, 2017
    Assignee: Hovione Inter Ltd.
    Inventors: Luis Sobral, Dionisio Martin, William Heggie, Emilia Leitäo