Patents by Inventor Emiliano Chiarot

Emiliano Chiarot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Outer membrane vesicles
    Patent number: 9764027
    Abstract: The present invention provides an outer membrane vesicle (OMV) from a Gram-negative bacterium, comprising at least one heterologous protein that is free in the lumen of the OMV, wherein the OMV is capable of eliciting an immune response to the heterologous protein when administered to a mammal. The invention also provides methods for preparing the OMVs of the invention, pharmaceutical compositions comprising the OMVs of the invention, especially immunogenic compositions and vaccines, and methods of generating an antibody immune response in a mammal using OMVs.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: September 19, 2017
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Guido Grandi, Immaculada Margarit Y Ros, Emiliano Chiarot
  • OUTER MEMBRANE VESICLES
    Publication number: 20150231232
    Abstract: The present invention provides an outer membrane vesicle (OMV) from a Gram-negative bacterium, comprising at least one heterologous protein that is free in the lumen of the OMV, wherein the OMV is capable of eliciting an immune response to the heterologous protein when administered to a mammal. The invention also provides methods for preparing the OMVs of the invention, pharmaceutical compositions comprising the OMVs of the invention, especially immunogenic compositions and vaccines, and methods of generating an antibody immune response in a mammal using OMVs.
    Type: Application
    Filed: September 18, 2013
    Publication date: August 20, 2015
    Inventors: Guido Grandi, Immaculada Margarit Y Ros,, Emiliano Chiarot
  • Mutant forms of streptolysin O
    Patent number: 8409589
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Grant
    Filed: September 14, 2011
    Date of Patent: April 2, 2013
    Assignee: Novartis AG
    Inventors: Giuliano Bensi, Immaculada Margarit Y Ros, Emiliano Chiarot, Guido Grandi, Maria Scarselli
  • MUTANT FORMS OF STREPTOLYSIN O
    Publication number: 20120003258
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Application
    Filed: September 14, 2011
    Publication date: January 5, 2012
    Applicant: NOVARTIS AG
    Inventors: Giuliano BENSI, Immaculada MARGARIT Y ROS, Emiliano CHIAROT, Guido GRANDI, Maria SCARSELLI
  • Mutant forms of streptolysin O
    Patent number: 8039005
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: October 18, 2011
    Assignee: Novartis AG
    Inventors: Giuliano Bensi, Immaculada Margarit Y Ros, Emiliano Chiarot, Guido Grandi, Maria Scarselli
  • MUTANT FORMS OF STREPTOLYSIN O
    Publication number: 20100158935
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Application
    Filed: February 24, 2010
    Publication date: June 24, 2010
    Applicant: NOVARTIS AG
    Inventors: Giuliano BENSI, Immaculada MARGARIT Y ROS, Emiliano CHIAROT, Guido GRANDI, Maria SCARSELLI
  • Mutant forms of streptolysin O
    Patent number: 7731978
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: June 8, 2010
    Assignee: Novartis AG
    Inventors: Giuliano Bensi, Immaculada Margarit Y Ros, Emiliano Chiarot, Guido Grandi, Maria Scarselli
  • MUTANT FORMS OF STREPTOLYSIN O
    Publication number: 20090162392
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Application
    Filed: December 19, 2008
    Publication date: June 25, 2009
    Applicant: NOVARTIS AG
    Inventors: Giuliano BENSI, Immaculada MARGARIT Y ROS, Emiliano CHIAROT, Guido GRANDI, Maria SCARSELLI