Patents by Inventor Emilio Margolles-Clark

Emilio Margolles-Clark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180312836
    Abstract: The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels.
    Type: Application
    Filed: April 30, 2018
    Publication date: November 1, 2018
    Inventors: Zhihong Cook, Yiwen Fang, Kenneth A. Feldmann, Edward Kiegle, Shing Kwok, Yu-Ping Lu, Leonard Medrano, Roger Pennell, Richard Schneeberger, Chuan-Yin Wu, Nestor Apuya, Jack K. Okamuro, Diane K. Jofuku, Jonathan Donson, David Van-Dinh Dang, Emilio Margolles-Clark, Nickolai Alexandrov, Tatiana Tatarinova, Noah Theiss, Danielle Grizard, Shawna Davis, Dennis Robles, Michael Portereiko
  • Publication number: 20180119159
    Abstract: The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels in plants, and plants containing such promoters or promoter control elements.
    Type: Application
    Filed: August 30, 2017
    Publication date: May 3, 2018
    Inventors: Richard SCHNEEBERGER, Emilio MARGOLLES-CLARK, Tatiana TATARINOVA, Yiwen FANG, Nickolai ALEXANDROV, Leonard MEDRANO, Roger PENNELL, Noah THEISS, Danielle GRIZARD, Shauna J. DAVIS, Dennis ROBLES, Michael PORTEREIKO
  • Publication number: 20180105829
    Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.
    Type: Application
    Filed: August 29, 2017
    Publication date: April 19, 2018
    Inventors: Gregory NADZAN, Richard SCHNEEBERGER, Han Suk KIM, David Van-dinh DANG, Kenneth A. FELDMANN, Roger PENNELL, Shing KWOK, Hongyu ZHANG, Cory CHRISTENSEN, Jack OKAMURO, Fasong ZHOU, Wuyi WANG, Emilio MARGOLLES-CLARK, Gerard MAGPANTAY, Julissa SOSA, Nestor APUYA, Kerstin PICCOLO, Bonnie HUND, Nickolai ALEXANDROV, Vyacheslav BROVER, Peter MASCIA
  • Publication number: 20170349908
    Abstract: Materials and methods for identifying lignin regulatory region-regulatory protein associations are disclosed. Materials and methods for modulating lignin accumulation are also disclosed. In addition, methods and materials for modulating (e.g., increasing or decreasing) the level of a component (e.g., protein, oil, lignin, carbon, a carotenoid, or a triterpenoid) in plants are disclosed.
    Type: Application
    Filed: April 27, 2017
    Publication date: December 7, 2017
    Inventors: Steven Craig Bobzin, Nestor Apuya, Karen Chiang, Elena Doukhanina, Kenneth Feldmann, Boris Jankowski, Emilio Margolles-Clark, Daniel Mumenthaler, Jack Okamuro, Joon-Hyun Park, Amr Saad Ragab, Joel Cruz Rarang, Richard Schneeberger, Jennifer E. Van Fleet, Ke Zhang
  • Patent number: 9777285
    Abstract: The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels in plants, and plants containing such promoters or promoter control elements.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: October 3, 2017
    Assignee: Ceres, Inc.
    Inventors: Richard Schneeberger, Emilio Margolles-Clark, Tatiana Tatarinova, Yiwen Fang, Nickolai Alexandrov, Leonard Medrano, Roger Pennell, Noah Theiss, Danielle Grizard, Shauna J. Davis, Dennis Robles, Michael Portereiko
  • Patent number: 9777287
    Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: October 3, 2017
    Assignee: Ceres, Inc.
    Inventors: Gregory Nadzan, Richard Schneeberger, Han Suk Kim, David Van-dinh Dang, Kenneth A. Feldmann, Roger Pennell, Shing Kwok, Hongyu Zhang, Cory Christensen, Jack Okamuro, Fasong Zhou, Wuyi Wang, Emilio Margolles-Clark, Gerard Magpantay, Julissa Sosa, Nestor Apuya, Kerstin Piccolo, Bonnie Hund, Nickolai Alexandrov, Vyacheslav Brover, Peter Mascia
  • Publication number: 20160369294
    Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased[RCL2] low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.
    Type: Application
    Filed: October 4, 2012
    Publication date: December 22, 2016
    Applicant: CERES, INC.
    Inventors: Gregory NADZAN, Richard SCHNEEBERGER, Han Suk KIM, David Van-dinh DANG, Kenneth A. FELDMANN, Roger PENNELL, Shing KWOK, Hongyu ZHANG, Cory CHRISTENSEN, Jack OKAMURO, Fasong ZHOU, Wuyi WANG, Emilio MARGOLLES-CLARK, Gerard MAGPANTAY, Julissa SOSA, Nestor APUYA, Kerstin PICCOLO, Bonnie HUND, Nickolai ALEXANDROV, Vyacheslav BROVER, Peter MASCIA
  • Publication number: 20150259699
    Abstract: Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low-nitrogen tolerance levels and plant products produced from plants having increased low-nitrogen tolerance levels.
    Type: Application
    Filed: February 20, 2015
    Publication date: September 17, 2015
    Applicant: CERES, INC.
    Inventors: Gregory NADZAN, Richard SCHNEEBERGER, Han Suk KIM, David Van-dinh DANG, Kenneth A. FELDMANN, Roger PENNELL, Shing KWOK, Hongyu ZHANG, Cory CHRISTENSEN, Jack OKAMURO, Fasong ZHOU, Wuyi WANG, Emilio MARGOLLES-CLARK, Gerard MAGPANTAY, Julissa SOSA, Nestor APUYA, Kerstin PICCOLO, Bonnie HUND, Nickolai ALEXANDROV, Vyacheslav BROVER, Peter MASCIA
  • Publication number: 20150007365
    Abstract: The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels in plants, and plants containing such promoters or promoter control elements.
    Type: Application
    Filed: September 3, 2014
    Publication date: January 1, 2015
    Inventors: Richard SCHNEEBERGER, Emilio MARGOLLES-CLARK, Tatiana TATARINOVA, Yiwen FANG, Nickolai ALEXANDROV, Leonard MEDRANO, Roger PENNELL, Noah THEISS, Danielle GRIZARD, Shauna J. DAVIS, Dennis ROBLES, Michael PORTEREIKO
  • Publication number: 20130212735
    Abstract: Materials and Methods for identifying lignin regulatory region-regulatory protein associations are disclosed. Materials and methods for modulating lignin accumulation are also disclosed. In addition, methods and materials for modulating (e.g., increasing or decreasing) the level of a component (e.g., protein, oil, lignin, carbon, a carotenoid, or a triterpenoid) in plants are disclosed.
    Type: Application
    Filed: August 13, 2012
    Publication date: August 15, 2013
    Inventors: Steven Craig Bobzin, Nestor Apuya, Karen Chiang, Elena Doukhanina, Kenneth Feldmann, Boris Jankowski, Emilio Margolles-Clark, Daniel Mumenthaler, Jack Okamuro, Joon-Hyun Park, Amr Saad Ragab, Joel Cruz Rarang, Richard Schneeberger, Jennifer E. Van Fleet, Ke Zhang
  • Patent number: 8471099
    Abstract: Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants with increased nitrogen use efficiency. The present invention further relates to nucleotide sequences and the use of those nucleotide sequences in the genetic-engineering of plants to display enhanced nitrogen assimilatory and utilization capacities, grow larger, more efficiently or rapidly, and/or have enriched nitrogen contents in vegetative and/or reproductive plant parts and/or increased biomass. More particularly, this invention relates to producing transgenic plants engineered to have altered expression of key components in the nitrogen assimilation and utilization pathways. The engineered plants may be productively cultivated under conditions of low nitrogen fertilizer input or in nitrogen poor soils.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: June 25, 2013
    Assignee: Ceres, Inc.
    Inventors: Richard Schneeberger, Emilio Margolles-Clark, Gerard Magpantay
  • Publication number: 20130031675
    Abstract: Methods and materials for modulating (e.g., increasing or decreasing) carbon levels in plants are disclosed. For example, nucleic acids encoding carbon-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased carbon levels.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 31, 2013
    Inventors: Richard Schneeberger, Emilio Margolles-Clark, Joon-Hyun Park, Boris Jankowski, Steven Craig Bobzin
  • Patent number: 8299320
    Abstract: Methods and materials for modulating (e.g., increasing or decreasing) carbon levels in plants are disclosed. For example, nucleic acids encoding carbon-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased carbon levels.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: October 30, 2012
    Assignee: Ceres, Inc.
    Inventors: Richard Schneeberger, Emilio Margolles-Clark, Joon-Hyun Park, Boris Jankowski, Steven Craig Bobzin
  • Publication number: 20110065675
    Abstract: Azo dyes and suramin-related small molecules are effective in inhibiting the CD40/CD154 protein-protein interaction, an important co-stimulatory interaction involved in the activation of immune responses mediated by T- and B-cells. The compounds were found to be active as indicated by their IC50 values both in a cell-free binding assay and in the inhibition of CD154-induced B-cell proliferation assay. The compounds may be used as therapeutic compounds for treatment of diseases and disorders related to immune or inflammatory responses. Methods of inhibiting the CD40/CD154 protein-protein interaction and treating diseases and disorders related to immune or inflammatory responses are described.
    Type: Application
    Filed: May 5, 2009
    Publication date: March 17, 2011
    Applicant: University of Miami
    Inventors: Peter Buchwald, Emilio Margolles-Clark, Norma S. Kenyon, Camillo Ricordi
  • Publication number: 20110041208
    Abstract: The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels.
    Type: Application
    Filed: September 27, 2010
    Publication date: February 17, 2011
    Applicant: CERES, INC.
    Inventors: Roger PENNELL, Kenneth A. Feldmann, Yu-Ping Lu, Yiwen Fang, Shing Kwok, Van-Dinh Dang, Zhihong Cook, Jack Okamuro, Nestor Apuya, Richard Schneeberger, Emilio Margolles-Clark, Edward A. Kiegle, Leonard Medrano
  • Patent number: 7838650
    Abstract: The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: November 23, 2010
    Assignee: Ceres, Inc.
    Inventors: Roger Pennell, Kenneth A. Feldmann, Yu-Ping Lu, Yiwen Fang, Shing Kwok, Van-Dinh Dang, Zhihong Cook, Jack Okamuro, Nestor Apuya, Richard Schneeberger, Emilio Margolles-Clark, Edward A. Kiegle, Leonard Medrano
  • Publication number: 20100146663
    Abstract: Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants with increased nitrogen use efficiency. The present invention further relates to nucleotide sequences and the use of those nucleotide sequences in the genetic-engineering of plants to display enhanced nitrogen assimilatory and utilization capacities, grow larger, more efficiently or rapidly, and/or have enriched nitrogen contents in vegetative and/or reproductive plant parts and/or increased biomass. More particularly, this invention relates to producing transgenic plants engineered to have altered expression of key components in the nitrogen assimilation and utilization pathways. The engineered plants may be productively cultivated under conditions of low nitrogen fertilizer input or in nitrogen poor soils.
    Type: Application
    Filed: November 10, 2009
    Publication date: June 10, 2010
    Applicant: CERES, INC.
    Inventors: Richard Schneeberger, Emilio MARGOLLES-CLARK, Gerard Magpantay
  • Patent number: 7696409
    Abstract: Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants with increased nitrogen use efficiency. The present invention further relates to nucleotide sequences and the use of those nucleotide sequences in the genetic-engineering of plants to display enhanced nitrogen assimilatory and utilization capacities, grow larger, more efficiently or rapidly, and/or have enriched nitrogen contents in vegetative and/or reproductive plant parts and/or increased biomass. More particularly, this invention relates to producing transgenic plants engineered to have altered expression of key components in the nitrogen assimilation and utilization pathways. The engineered plants may be productively cultivated under conditions of low nitrogen fertilizer input or in nitrogen poor soils.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: April 13, 2010
    Assignee: Ceres, Inc.
    Inventors: Richard Schneeberger, Emilio Margolles-Clark, Gerard Magpantay
  • Publication number: 20090070892
    Abstract: The present invention is directed to nitrogen responsive promoter sequences and promoter control elements, polynucleotide constructs comprising the nitrogen responsive promoters and control elements and methods of identifying the nitrogen responsive promoters, control elements, or fragments thereof. The invention further relates to the use of the present nitrogen responsive promoters or promoter control elements to modulate transcript levels.
    Type: Application
    Filed: September 13, 2007
    Publication date: March 12, 2009
    Inventors: Emilio Margolles CLARK, Richard Schneeberger
  • Publication number: 20080241347
    Abstract: Methods and materials for modulating (e.g., increasing or decreasing) carbon levels in plants are disclosed. For example, nucleic acids encoding carbon-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased carbon levels.
    Type: Application
    Filed: December 28, 2007
    Publication date: October 2, 2008
    Applicant: Ceres, Inc., a Delaware corporation
    Inventors: Richard Schneeberger, Emilio Margolles-Clark, Joon-Hyun Park, Boris Jankowski, Steven Craig Bobzin