Abstract: A method for health assessment and nutritional fortification during pregnancy enables a mother to interactively work with a caregiver to manage pregnancy from preconception through the period of breastfeeding, so as to enhance the mother's maternal health and achieve an appropriate birth weight for the baby. The method provides a battery of health tests designed to identify needs and special conditions of the mother. The health test includes genomics analysis. A customized nutritional plan and supplemental program supply both the mother and the baby with the necessary vitamins and nutrients during and after birth. The mother records information pertinent to food intake and general pregnancy. The recorded information is used by the caregiver for analysis, and also to educate the mother and network of mothers. The mother and caregiver interact to formulate an individual pregnancy plan during the duration of the pregnancy based on the health assessments and supplements.