Patents by Inventor Emily E. Bosco

Emily E. Bosco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of small molecule inhibitors targeting the interaction between RAC GTPase and p67
    Patent number: 9567347
    Abstract: Inhibitors of p67phox protein are provided herein, as well as pharmaceutical compositions and methods relating thereto.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: February 14, 2017
    Assignee: Children's Hospital Medical Center
    Inventors: Yi Zheng, Prakash Jagtap, Emily E. Bosco, Jaroslaw Meller, Marie-Dominique Filippi
  • USE OF SMALL MOLECULE INHIBITORS TARGETING THE INTERACTION BETWEEN RAC GTPASE AND P67(PHOX)
    Publication number: 20160297835
    Abstract: Inhibitors of p67phox protein are provided herein, as well as pharmaceutical compositions and methods relating thereto.
    Type: Application
    Filed: April 8, 2016
    Publication date: October 13, 2016
    Inventors: Yi Zheng, Prakash Jagtap, Emily E. Bosco, Jaroslaw Meller, Marie-Dominique Filippi
  • Use of small molecule inhibitors targeting the interaction between Rac GTPase and p67 (phox)
    Patent number: 9453022
    Abstract: Inhibitors of p67phox protein are provided herein, as well as pharmaceutical compositions and methods recited thereto.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: September 27, 2016
    Assignee: CHILDREN'S HOSPITAL MEDICAL CENTER
    Inventors: Yi Zheng, Prakash Jagtap, Emily E. Bosco, Jaroslaw Meller, Marie-Dominique Filippi
  • Use of small molecule inhibitors targeting the interaction between Rac GTPase and p67 (phox)
    Patent number: 9334284
    Abstract: Inhibitors of p67phox protein are provided herein, as well as pharmaceutical compositions and methods recited thereto.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: May 10, 2016
    Assignee: Children's Hospital Medical Center
    Inventors: Yi Zheng, Prakash Jagtap, Emily E. Bosco, Jaroslaw Meller, Marie-Dominique Filippi
  • USE OF SMALL MOLECULE INHIBITORS TARGETING THE INTERACTION BETWEEN RAC GTPASE AND P67 (PHOX)
    Publication number: 20150025067
    Abstract: Inhibitors of p67phox protein are provided herein, as well as pharmaceutical compositions and methods relating thereto.
    Type: Application
    Filed: February 13, 2013
    Publication date: January 22, 2015
    Applicant: CHILDREN'S HOSPITAL MEDICAL CENTER
    Inventors: Yi Zheng, Prakash Jagtap, Emily E. Bosco, Jaroslaw Meller, Marie-Dominique Filippi
  • Methods of predicting resistance or sensitivity to therapies for cancer
    Patent number: 8470534
    Abstract: The present application is directed to methods of predicting the resistance of a tumor to molecularly targeted therapy and methods of predicting sensitivity of a tumor to DNA damaging therapy. The methods include: a) determining the level of expression of plurality of genes regulated by retinoblastoma tumor supressor (RB) in the individual, and b) comparing the level of expression of the plurality of genes regulated by RB in the individual with a level of expression of the plurality of genes regulated by RB in a control. The application is also directed to an RNA expression profile for the loss of RB.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: June 25, 2013
    Inventors: Erik S. Knudsen, Emily E. Bosco
  • Methods of Predicting Resistance or Sensitivity to Therapies for Cancer
    Publication number: 20090149333
    Abstract: The present application is directed to methods of predicting the resistance of a tumor to molecularly targeted therapy and methods of predicting sensitivity of a tumor to DNA damaging therapy. The methods include: a) determining the level of expression of plurality of genes regulated by retinoblastoma tumor supressor (RB) in the individual, and b) comparing the level of expression of the plurality of genes regulated by RB in the individual with a level of expression of the plurality of genes regulated by RB in a control. The application is also directed to an RNA expression profile for the loss of RB.
    Type: Application
    Filed: December 3, 2007
    Publication date: June 11, 2009
    Inventors: Erik S. Knudsen, Emily E. Bosco