Abstract: A method for producing a porous copolymer monolith substrate for use in flow through liquid chromatography applications is disclosed. The method comprises forming a reaction composition comprising at least one monoethylenically unsaturated aryl monomer, at least one polyethylenically unsaturated aryl monomer, a RAFT agent, at least one liquid porogen, and a radical initiator. The reaction composition is introduced to a mold having a shape and dimensions suitable for forming a liquid chromatography substrate. The monoethylenically unsaturated aryl monomer, the polyethylenically unsaturated aryl monomer and the RAFT agent are copolymerised in the mold under conditions to form a solid copolymer network that is phase-separated from the reaction composition and/or any liquid components.

Abstract: A sampling device for collecting, storing and processing fluid samples for analysis is disclosed. The sampling device comprises a porous polymer monolith sampling substrate housed within a substantially impermeable housing. The housing surrounds the sampling substrate and further comprises a sampling aperture via which the sampling substrate is accessible externally from the sampling device.

Abstract: The present invention generally relates to the use of porous polymer materials as a medium for the storage of biological samples. The present invention also relates to a method of drying and storage of biological samples on the porous polymer materials. The biological samples include blood and blood plasma samples.

Abstract: A sampling device comprising a body that defines a fluid flow path from an inlet opening, wherein the flow path includes a bed of a porous polymer monolith selected to adsorb bioparticles from a matrix drawn or dispensed through the inlet opening and the bed.

Abstract: The present invention generally relates to porous polymer monoliths. The present invention also relates to processes for the preparation of porous polymer monoliths, storage mediums formed from porous polymer monoliths and use thereof in the drying and storage of body fluids including blood and blood plasma samples.

Abstract: A sampling device comprising a body that defines a fluid flow path from an inlet opening, wherein the flow path includes a bed of a porous polymer monolith selected to adsorb bioparticles from a matrix drawn or dispensed through the inlet opening and the bed.

Abstract: A sampling device comprising a body that defines a fluid flow path from an inlet opening, wherein the flow path includes a bed of a porous polymer monolith selected to adsorb bioparticles from a matrix drawn or dispensed through the inlet opening and the bed.

Abstract: The present invention generally relates to the use of porous polymer materials as a medium for the storage of biological samples. The present invention also relates to a method of drying and storage of biological samples on the porous polymer materials. The biological samples include blood and blood plasma samples.

Abstract: The present invention generally relates to porous polymer monoliths. The present invention also relates to processes for the preparation of porous polymer monoliths, storage mediums formed from porous polymer monoliths and use thereof in the drying and storage of body fluids including blood and blood plasma samples.