Patents by Inventor Emily HOLZ

Emily HOLZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS WITH REDUCED DEGRADATION OF POLYSORBATE
    Publication number: 20220040312
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Application
    Filed: January 22, 2021
    Publication date: February 10, 2022
    Applicant: Genentech, Inc.
    Inventors: Brian CONNOLLY, Lydia HAMBURG, Emily HOLZ
  • Formulations with reduced degradation of polysorbate
    Patent number: 10933141
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: March 2, 2021
    Assignee: GENENTECH, INC.
    Inventors: Brian Connolly, Lydia Hamburg, Emily Holz
  • FORMULATIONS WITH REDUCED DEGRADATION OF POLYSORBATE
    Publication number: 20200215195
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Application
    Filed: November 21, 2019
    Publication date: July 9, 2020
    Applicant: Genentech, Inc.
    Inventors: Brian CONNOLLY, Lydia HAMBURG, Emily HOLZ
  • Formulations with reduced degradation of polysorbate
    Patent number: 10525137
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: January 7, 2020
    Assignee: Genentech, Inc.
    Inventors: Brian Connolly, Lydia Hamburg, Emily Holz
  • FORMULATIONS WITH REDUCED DEGRADATION OF POLYSORBATE
    Publication number: 20170189536
    Abstract: The invention provides methods for making such formulations and methods of using such formulations. The invention further provides methods of reducing polysorbate degradation, methods of reducing the amount of visible and sub-visible particles in an aqueous formulation, and methods of disaggregating polysorbate degradation products comprising adding a cyclodextrin to a formula comprising polysorbate and a polypeptide. The invention also provides aqueous formulations comprising a polypeptide, a polysorbate, and a cyclodextrin with reduced polysorbate degradation.
    Type: Application
    Filed: December 28, 2016
    Publication date: July 6, 2017
    Inventors: Brian CONNOLLY, Lydia HAMBURG, Emily HOLZ