Patents by Inventor Emily J. HANAN

Emily J. HANAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazolochlorophenyl compounds, compositions and methods of use thereof
    Patent number: 11649241
    Abstract: Compounds of Formula I and methods of use as Janus kinase inhibitors are described herein.
    Type: Grant
    Filed: February 12, 2021
    Date of Patent: May 16, 2023
    Assignee: Genentech, Inc.
    Inventors: Mark Zak, F. Anthony Romero, Po-wai Yuen, Emily J. Hanan
  • MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20230133667
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: October 18, 2022
    Publication date: May 4, 2023
    Inventors: Peter Andrew Smith, Tucker Curran Roberts, Robert I. Higuchi, Prasuna Paraselli, Michael F. T. Koehler, Jacob Bradley Schwarz, James John Crawford, Cuong Q. Ly, Emily J. Hanan, Huiyong Hu, Yongsheng Chen, Zhiyong Yu, Paul Colin Michael Winship, Calum MacCleod, Toby Blench
  • MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20230133817
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: December 8, 2022
    Publication date: May 4, 2023
    Inventors: Yongsheng Chen, Peter Andrew Smith, Tuker Curran Roberts, Robert I. Higuchi, Prasuna Paraselli, Michael F.T Koehler, Jacob Bradley Schwarz, James John Crawford, Cuong Q. Ly, Emily J. Hanan, Huiyong Hu, Zhiyong Yu
  • CYCLIC PEPTIDE ANTIBIOTICS
    Publication number: 20230025834
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of lipoprotein signal peptidase II (LspA), a key protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: September 10, 2021
    Publication date: January 26, 2023
    Applicant: Genentech, Inc.
    Inventors: Guosheng WU, Emily J. HANAN, Marie-Gabrielle BRAUN, Sharada S. LABADIE, Keira GARLAND, Richard M. PASTOR, Paul Anthony GIBBONS, Yuhong FU, Yun-Xing CHENG
  • ANTIBACTERIAL PEPTIDES AND METHODS OF USE
    Publication number: 20220135622
    Abstract: The invention provides antibacterial compositions comprising peptides that bind to a lipopolysaccharide and methods of using the same.
    Type: Application
    Filed: February 26, 2020
    Publication date: May 5, 2022
    Applicant: Genentech, Inc.
    Inventors: Thomas CLAIRFEUILLE, Emily J. HANAN, Jian Mehr-Dean PAYANDEH, Steven Thomas RUTHERFORD, Benjamin Douglas SELLERS, Nicholas John SKELTON
  • Cyclic peptide antibiotics
    Patent number: 11279735
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of lipoprotein signal peptidase II (LspA), a key protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: March 22, 2022
    Assignee: Genentech, Inc.
    Inventors: Emily J. Hanan, Georgette Castanedo, Marie Gabrielle Braun, Keira Garland, Peter Andrew Smith, Richard Pastor, Paul Gibbons, Yunxing Cheng, Guosheng Wu, Yuhong Fu, Po-Wai Yuen
  • MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20210198316
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: August 13, 2019
    Publication date: July 1, 2021
    Inventors: Peter Andrew SMITH, Tucker Curran ROBERTS, Robert I. HIGUCHI, Prasuna PARASELLI, Michael F. T. KOEHLER, Jacob Bradley SCHWARZ, James John CRAWFORD, Cuong Q. LY, Emily J. HANAN, Huiyong HU, Yongsheng CHEN, Zhiyong YU, Paul Colin Michael WINSHIP, Calum McCleod, Toby Blench
  • PYRAZOLOCHLOROPHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20210179626
    Abstract: Compounds of Formula I and methods of use as Janus kinase inhibitors are described herein.
    Type: Application
    Filed: February 12, 2021
    Publication date: June 17, 2021
    Applicant: Genentech, Inc.
    Inventors: Mark ZAK, F. Anthony ROMERO, Po-wai YUEN, Emily J. HANAN
  • CYCLIC PEPTIDE ANTIBIOTICS
    Publication number: 20200331968
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of lipoprotein signal peptidase II (LspA), a key protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: March 12, 2020
    Publication date: October 22, 2020
    Applicant: Genentech, Inc.
    Inventors: Emily J. HANAN, Georgette CASTANEDO, Marie Gabrielle BRAUN, Keira GARLAND, Peter Andrew SMITH, Richard PASTOR, Paul GIBBONS, Yunxing CHENG, Guosheng WU, Yuhong FU, Po-Wai YUEN
  • MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20200024309
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: August 13, 2019
    Publication date: January 23, 2020
    Inventors: Peter Andrew SMITH, Tucker Curran ROBERTS, Robert I. HIGUCHI, Prasuna PARASELLI, Michael F. T. KOEHLER, Jacob Bradley SCHWARZ, James John CRAWFORD, Cuong Q. LY, Emily J. HANAN, Huiyong HU, Yongsheng CHEN, Zhiyong YU, Paul Colin Michael WINSHIP, Calum McCleod, Toby Blench
  • PYRAZOLOCHLOROPHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20200002346
    Abstract: Compounds of Formula I and methods of use as Janus kinase inhibitors are described herein.
    Type: Application
    Filed: September 5, 2019
    Publication date: January 2, 2020
    Applicant: Genentech, Inc.
    Inventors: Mark ZAK, F. Anthony ROMERO, Po-wai YUEN, Emily J. HANAN
  • MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
    Publication number: 20180327367
    Abstract: Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
    Type: Application
    Filed: November 21, 2016
    Publication date: November 15, 2018
    Inventors: Yongsheng CHEN, Peter Andrew SMITH, Tucker Curran ROBERTS, Robert I. HIGUCHI, Prasuna PARASELLI, Michael F. T. KOEHLER, Jacob Bradley SCHWARZ, James John CRAWFORD, Cuong Q. LY, Emily J. HANAN, Huiyong HU, Zhiyong YU