Abstract: Provided are flexible hybrid interconnect circuits and methods of forming thereof. A flexible hybrid interconnect circuit comprises multiple conductive layers, stacked and spaced apart along the thickness of the circuit. Each conductive layer comprises one or more conductive elements, one of which is operable as a high frequency (HF) signal line. Other conductive elements, in the same and other conductive layers, form an electromagnetic shield around the HF signal line. Some conductive elements in the same circuit are used for electrical power transmission. All conductive elements are supported by one or more inner dielectric layers and enclosed by outer dielectric layers. The overall stack is thin and flexible and may be conformally attached to a non-planar surface. Each conductive layer may be formed by patterning the same metallic sheet. Multiple pattern sheets are laminated together with inner and outer dielectric layers to form a flexible hybrid interconnect circuit.

Abstract: Library preparation systems and methods are disclosed. In an implementation, a modular bay for preparing a library of samples for sequencing, the modular bay comprising a contact dispenser and a working area comprising a working plate receptacle adapted to receive a working plate, a thermocycler, a magnet, and a drawer. The drawer comprising a consumables area adapted to receive a sample plate adapted to contain a sample, and a plurality of consumables for interacting with the sample in the working plate. The contact dispenser is linearly movable in a longitudinal direction between the consumables area and the working area, such that the contact dispenser is configured to (i) move the sample from the sample plate in the consumables area to the working plate in the working area, and (ii) move the plurality of consumables between the consumables area and the working plate in the working area.

Abstract: A security print medium for forming security documents therefrom, the security print medium comprising a core having opposing first and second sides. The core comprises a radiation-responsive substance distributed within the core across at least a first region of the core, the radiation-responsive substance being responsive to a predetermined input radiation by producing a predetermined output radiation. The security print medium further comprises a first encoding layer disposed on the first side of the core and a second encoding layer disposed on the second side of the core, each of the first and second encoding layers comprising an encoding material that modifies the intensity of the predetermined input radiation and/or the predetermined output radiation produced by the radiation-responsive substance transmitted through the respective encoding layer, wherein the first and second encoding layers overlap each other across the first region.

Abstract: A security print medium for forming security documents therefrom, the security print medium comprising a core having opposing first and second sides. The core comprises a radiation-responsive substance distributed within the core across at least a first region of the core, the radiation-responsive substance being responsive to a predetermined input radiation by producing a predetermined output radiation. The security print medium further comprises a first encoding layer disposed on the first side of the core and a second encoding layer disposed on the second side of the core, each of the first and second encoding layers comprising an encoding material that modifies the intensity of the predetermined input radiation and/or the predetermined output radiation produced by the radiation-responsive substance transmitted through the respective encoding layer, wherein the first and second encoding layers overlap each other across the first region.

Abstract: A combination of capillary forces and gas pressure is used to control the movement of liquid samples within a microfluidic device. A liquid sample introduced to a proximal portion of a capillary channel of a microfluidic device moves by capillary action partway along the capillary channel. As the liquid sample moves, a pressure of a gas acting upon a distal gas-liquid interface of the liquid sample increases by an amount sufficient to stop further movement of the liquid sample. To initiate further movement of the liquid sample, a pump connected to a distal portion of the capillary channel decreases the pressure of the gas acting upon the distal gas-liquid interface of the liquid sample by an amount sufficient to permit the liquid sample to move by capillary action further along the capillary channel of the microfluidic device.

Abstract: A combination of capillary forces and gas pressure is used to control the movement of liquid samples within a microfluidic device. A liquid sample introduced to a proximal portion of a capillary channel of a microfluidic device moves by capillary action partway along the capillary channel. As the liquid sample moves, a pressure of a gas acting upon a distal gas-liquid interface of the liquid sample increases by an amount sufficient to stop further movement of the liquid sample. To initiate further movement of the liquid sample, a pump connected to a distal portion of the capillary channel decreases the pressure of the gas acting upon the distal gas-liquid interface of the liquid sample by an amount sufficient to permit the liquid sample to move by capillary action further along the capillary channel of the microfluidic device.

Abstract: A combination of capillary forces and gas pressure is used to control the movement of liquid samples within a microfluidic device. A liquid sample introduced to a proximal portion of a capillary channel of a microfluidic device moves by capillary action partway along the capillary channel. As the liquid sample moves, a pressure of a gas acting upon a distal gas-liquid interface of the liquid sample increases by an amount sufficient to stop further movement of the liquid sample. To initiate further movement of the liquid sample, a pump connected to a distal portion of the capillary channel decreases the pressure of the gas acting upon the distal gas-liquid interface of the liquid sample by an amount sufficient to permit the liquid sample to move by capillary action further along the capillary channel of the microfluidic device.

Abstract: The present invention relates to an action-figure type board game wherein players advance their game pieces around a dividedly spaced instructional peripheral track in accordance with a die being thrown, subsequently allowing a player's poseable cheerleader figure to be launched and propelled gymnastically-like airborne at a plurality of athletic competition stations, and then land upright on landing surfaces using interlocking “hook and loop” fastener material, simulating the physical skills and tumbling routines that are performed by Competitive Cheerleaders, and in order to win, collect the majority plurality of awards referred to as “trophy” cards.

Abstract: The present invention relates to the biosynthesis of indole diterpene compounds. In particular, the invention relates to genes encoding enzymes considered responsible for the synthesis of lolitrems.