Abstract: In particular, the compound is effective to inhibit Dxr in Mycobacterium tuberculosis (Mtb). The present invention relates to compounds having general formula (I) or (II) where X is an acidic group, such as carboxylate, phosphonate, sulfate, and tetrazole; Ar is a substituted or unsubstituted aromatic or heteroaromatic group; and n is 0, 1, 2, 3, or 4, preferably 2, 3, or 4. The compounds inhibits 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr), particularly Dxr in Mycobacterium tuberculosis (Mtb).

Abstract: In particular, the compound is effective to inhibit Dxr in Mycobacterium tuberculosis (Mtb). The present invention relates to compounds having general formula (I) or (II) where X is an acidic group, such as carboxylate, phosphonate, sulfate, and tetrazole; Ar is a substituted or unsubstituted aromatic or heteroaromatic group; and n is 0, 1, 2, 3, or 4, preferably 2, 3, or 4. The compounds inhibits 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr), particularly Dxr in Mycobacterium tuberculosis (Mtb).

Abstract: A portable food warming apparatus has a base container removably receiving a tray insert having a tray floor spaced from the base container floor to define a chamber therebetween filled with a heat exchange liquid. An electric resistance heating element coil is mounted on the container floor to effect warming of the liquid and thereby the tray insert. A vehicular cigarette lighter adapter plug permits energization of the heating element coil at remote locations. The base container includes a rotatable locking member for releasable locking the tray insert to the base container. A light source on the base container coupled to a fiber-optic cable surrounding the periphery of the tray insert may be provided for illuminating the tray insert contents during conditions of limited light. A removable lid covers the tray insert.