Patents by Inventor Emma Budd

Emma Budd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridine and Pyrazine Derivative for the Treatment of CF
    Publication number: 20120277232
    Abstract: The present invention provides pyridine and pyrazine derivatives which restore or enhance the function of mutant and/or wild type CFTR to treat cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia and keratoconjunctivitis sire, or constipation (IBS, IBD, opioid induced). Pharmaceutical compositions comprising such derivatives are also encompassed.
    Type: Application
    Filed: July 9, 2012
    Publication date: November 1, 2012
    Inventors: Urs BAETTIG, Kamlesh Jagdis BALA, Emma BUDD, Lee EDWARDS, Catherine Howsham, Glyn HUGHES, Darren Mark LEGRAND, Katrin SPIEGEL
  • Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme
    Patent number: 8268834
    Abstract: The present invention concerns a compound of formula (I) or a salt, suitably a pharmaceutically acceptable salt, or solvate thereof, wherein the groups R1, R2, Ar?, A and Y are defined in the description, to compositions and use of the compounds in the treatment of inflammatory and allergic conditions.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: September 18, 2012
    Assignee: Novartis AG
    Inventors: Ian Bruce, Emma Budd, Lee Edwards, Catherine Howsham
  • Organic Compounds
    Publication number: 20120214800
    Abstract: The present invention concerns a compound of formula (I) or a salt, suitably a pharmaceutically acceptable salt, or solvate thereof, wherein the groups R1, R2, Ar?, A and Y are defined in the description, to compositions and use of the compounds in the treatment of inflammatory and allergic conditions.
    Type: Application
    Filed: April 30, 2012
    Publication date: August 23, 2012
    Inventors: Ian Bruce, Emma Budd, Lee Edwards, Catherine Howsham
  • Pyridine and pyrazine derivative for the treatment of CF
    Patent number: 8247436
    Abstract: The present invention provides pyridine and pyrazine derivatives which restore or enhance the function of mutant and/or wild type CFTR to treat cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia and keratoconjunctivitis sire, or constipation (IBS, IBD, opioid induced). Pharmaceutical compositions comprising such derivatives are also encompassed.
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: August 21, 2012
    Assignee: Novartis AG
    Inventors: Urs Baettig, Kamlesh Jagdis Bala, Emma Budd, Lee Edwards, Catherine Howsham, Glyn Hughes, Darren Mark Legrand, Katrin Spiegel
  • Pyrazine-2-carboxamide derivatives to treat diseases mediated by blockade of the epithelial sodium channel
    Patent number: 8039472
    Abstract: A compound of Formula I in free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: October 18, 2011
    Assignee: Novartis AG
    Inventors: Gurdip Bhalay, Emma Budd, Graham Charles Bloomfield, Stephen Paul Collingwood, Andrew Dunstan, Lee Edwards, Peter Gedeck, Catherine Howsham, Peter Hunt, Thomas Anthony Hunt, Paul Oakley, Nichola Smith
  • Treating diseases mediated by blockade of the epithelial sodium channel with pyrazine-2-carboxamide derivatives
    Publication number: 20110237572
    Abstract: A compound of Formula I in free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Application
    Filed: June 10, 2011
    Publication date: September 29, 2011
    Applicant: Novartis AG
    Inventors: Gurpid Bhalay, Emma Budd, Graham Charles Bloomfield, Stephen Paul Collingwood, Andrew Dunstan, Lee Edwards, Peter Gedeck, Catherine Howsham, Peter Hunt, Thomas Anthony Hunt, Paul Oakley, Nichola Smith
  • Pyridine and Pyrazine derivative for the Treatment of CF
    Publication number: 20110230483
    Abstract: The present invention provides pyridine and pyrazine derivatives which restore or enhance the function of mutant and/or wild type CFTR to treat cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia and keratoconjunctivitis sire, or constipation (IBS, IBD, opioid induced). Pharmaceutical compositions comprising such derivatives are also encompassed.
    Type: Application
    Filed: March 14, 2011
    Publication date: September 22, 2011
    Inventors: Urs BAETTIG, Kamlesh Jagdis BALA, Emma BUDD, Lee EDWARDS, Catherine Howsham, Glyn HUGHES, Darren Mark LEGRAND, Katrin SPIEGEL
  • 5-phenyl-thiazol-2-yl-urea derivatives and use as PI3 kinase inhibitors
    Patent number: 7998990
    Abstract: The present invention concerns a compound of formula Ia wherein: Ra* is hydrogen or C1-C4-alkyl; Rb* is —(C1-C4-alkylene)-Y—C1-C4-haloalkyl or —(C1-C4-alkylene)-Y—C1-C4-hydroxyalkyl; Y represents —CONH— or a five membered heteroaryl group.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: August 16, 2011
    Assignee: Novartis AG
    Inventors: Emma Budd, Judy Fox Hayler, Ian Bruce, Darren Mark Legrand, Brian Cox
  • INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE
    Publication number: 20110105535
    Abstract: Compounds of formula I in free or salt form, wherein R1, R2, R3 and R4 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
    Type: Application
    Filed: January 12, 2011
    Publication date: May 5, 2011
    Inventors: Ian BRUCE, Bernard Cuenoud, Thomas Hugo Keller, Gaynor Elizabeth Pilgrim, Nicola Press, Darren Mark Le Grand, Cathy Ritchie, Barbara Valade, Judy Hayler, Emma Budd
  • Organic compounds
    Patent number: 7754746
    Abstract: Compounds of formula I in free or salt form, wherein R1, R2, R3, R4 and X have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Grant
    Filed: December 13, 2006
    Date of Patent: July 13, 2010
    Assignee: Novartis AG
    Inventors: Emma Budd, Julia Doris Ida Hatto, Judy Fox Hayler, Darren Mark Legrand, Barbara Valade
  • Organic Compounds
    Publication number: 20100130506
    Abstract: A compound of Formula I in free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Application
    Filed: December 10, 2008
    Publication date: May 27, 2010
    Inventors: Gurdip BHALAY, Emma Budd, Graham Charles Bloomfield, Stephen Paul Collingwood, Andrew Dunstan, Lee Edwards, Peter Gedeck, Catherine Howsham, Peter Hunt, Thomas Anthony Hunt, Paul Oakley, Nichola Smith
  • Organic compounds
    Publication number: 20090239847
    Abstract: The present invention concerns a compound of formula (I) or a salt, suitably a pharmaceutically acceptable salt, or solvate thereof, wherein the groups R1, R2, Ar?, A and Y are defined in the description, to compositions and use of the compounds in the treatment of inflammatory and allergic conditions.
    Type: Application
    Filed: March 4, 2009
    Publication date: September 24, 2009
    Inventors: Ian BRUCE, Emma BUDD, Lee EDWARDS, Catherine HOWSHAM
  • 5-PHENYL-THIAZOL-2-YL-UREA DERIVATIVES AND USE AS PI3 KINASE INHIBITORS
    Publication number: 20090234132
    Abstract: The present invention concerns a compound of formula Ia wherein: Ra* is hydrogen or C1-4-alkyl; Rb* is —(C1-C4-alkylene)-Y—C1-4-haloalkyl or —(C1-C4-alkylene)-Y—C1-C4-hydroxyalkyl; Y represents —CONH— or a five membered heteroaryl group.
    Type: Application
    Filed: May 21, 2007
    Publication date: September 17, 2009
    Applicant: NOVARTIS AG
    Inventors: Emma Budd, Judy Fox Hayler, Ian Bruce, Darren Mark Legrand, Brian Cox
  • Organic Compounds
    Publication number: 20080319033
    Abstract: Compounds of formula I in free or salt form, wherein R1, R2, R3, R4 and X have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Application
    Filed: December 13, 2006
    Publication date: December 25, 2008
    Inventors: Emma Budd, Julia Doris Ida Hatto, Judy Fox Hayler, Darren Mark Legrand, Barbara Valade
  • Inhibitors of phosphatidylinositol 3-kinase
    Publication number: 20070032487
    Abstract: Compounds of formula I in free or salt form, wherein R1, R2, R3 and R4 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
    Type: Application
    Filed: April 30, 2004
    Publication date: February 8, 2007
    Inventors: Ian Bruce, Bernard Cuenoud, Thomas Keller, Gaynor Pilgrim, Nicola Press, Darren Le Grand, Cathy Ritchie, Barbara Valade, Judy Hayler, Emma Budd