Abstract: Systems and methods are directed to screening a subject for motor and cognitive impairment. A method for screening motor and cognitive impairment comprises administering a spiral tracing assessment to a subject, and receiving a response thereto; assessing the subject's performance based on the response; collecting performance parameters based on the subject's performance on the spiral tracing assessment; providing the performance parameters and the response to a pretrained machine learning model; predicting, using the pretrained machine learning model, a likelihood of the patient having a cognitive impairment; determining a motor and cognitive impairment status of the patient based on the prediction; and outputting the motor and cognitive impairment status.

Abstract: A method of marking a solid article or substance includes the steps of dissolving a water-insoluble medium in a first solvent to form a first mixture, mixing a nucleic acid solution with an intermediate solution to form a second mixture, mixing the second mixture with the first mixture to form a homogenous third mixture, marking the article or substance with the third mixture containing the nucleic acid; and drying the marked article or substance. Through the addition of an intermediate solution, the miscibility between the nucleic acid solution and the medium is increased and a homogenous solution is formed. For marking solid substances or articles, the water-insoluble medium containing known nucleic acid taggants is spread on the target solid substances or articles. For marking liquid, the target liquid is mixed with the water-insoluble media containing known nucleic acid taggants. As a result, the target liquid is labeled with nucleic acid.

Abstract: The present invention relates to a method of marking solid or liquid substances with nucleic acid for anti-counterfeiting and authentication, specifically to a method for marking solid or liquid substances with nucleic acid dissolved in a water insoluble medium. Through the addition of an intermediate solution, the miscibility between the nucleic acid solution and the medium is increased and forms a homogenous solution. For marking solid substances or articles, the water-insoluble medium containing known nucleic acid taggants is spread on the target solid substances or articles. After drying, nucleic acids protected by the water-insoluble medium adhere on surface of the object. For marking liquid, the target liquid is mixed with the water-insoluble media containing known nucleic acid taggants. As a result, the target liquid is labeled with nucleic acid.

Abstract: This invention features a method of labeling objects for anti-counterfeit purpose, especially refers to a method employing ribonucleic acid for product anti-counterfeit labeling and authenticity verification by PCR method. The procedure involves label objects with medium which contains ribonucleic acid. For verification of authenticity, the medium is removed and extracted for ribonucleic acid which is then amplified by PCR method for comparison.