Patents by Inventor Emma Parmee

Emma Parmee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyrazoles, compositions containing such compounds and methods of use
    Patent number: 7989475
    Abstract: The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
    Type: Grant
    Filed: March 19, 2009
    Date of Patent: August 2, 2011
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Emma Parmee, Subharekha Raghavan, Teresa Beeson, Dong-Ming Shen
  • SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE
    Publication number: 20090215825
    Abstract: The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
    Type: Application
    Filed: March 19, 2009
    Publication date: August 27, 2009
    Inventors: Emma Parmee, Subharekha Raghavan, Teresa Beeson, Dong-Ming Shen
  • Substituted pyrazoles, compositions containing such compounds and methods of use
    Patent number: 7572922
    Abstract: The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
    Type: Grant
    Filed: January 23, 2004
    Date of Patent: August 11, 2009
    Assignee: Merck & Co., Inc.
    Inventors: Emma Parmee, Subharekha Raghavan, Teresa Beeson, Dong-Ming Shen
  • Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
    Publication number: 20080085926
    Abstract: Glucagon receptor antagonist compounds are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.
    Type: Application
    Filed: October 2, 2007
    Publication date: April 10, 2008
    Inventors: John Stelmach, Emma Parmee, James Tata, Keith Rosauer, Ronald Kim, Amy Bittner, Jiang Chang, Christopher Sinz
  • Pyrazole Amide Derivatives, Compositions Containing Such Compounds And Methods Of Use
    Publication number: 20070203186
    Abstract: Pyrazole amides are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.
    Type: Application
    Filed: July 1, 2005
    Publication date: August 30, 2007
    Applicant: MERCK & CO., INC.
    Inventors: Teresa Beeson, Linda Brockunier, Emma Parmee, Subharekha Raghavan
  • Dipeptidyl peptidase inhibitors for the treatment of diabetes
    Patent number: 7253172
    Abstract: Compounds having Formula I, including pharmaceutically acceptable salts and prodrugs thereof: (I) are inhibitors of the dipeptidyl peptidase-IV enzyme (DP-IV), and are useful in the treatment of DP-IV mediated diseases and conditions, such as non-insulin dependent diabetes mellitus
    Type: Grant
    Filed: June 19, 2002
    Date of Patent: August 7, 2007
    Assignee: Merck & Co., Inc.
    Inventors: Linda Brockunier, Emma Parmee, Ann E. Weber
  • Cyclic guanidines, compositions containing such compounds and methods of use
    Publication number: 20070105930
    Abstract: The present invention relates to cyclic guanidines, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
    Type: Application
    Filed: December 15, 2004
    Publication date: May 10, 2007
    Inventors: Emma Parmee, Ronald Kim, Elizabeth Rouse, Darby Schmidt, Christopher Sinz, Jiang Chang
  • Benzamidazoles, compositions containing such compounds and methods of use
    Publication number: 20070093544
    Abstract: The present invention relates to substituted benzimidazoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
    Type: Application
    Filed: May 5, 2004
    Publication date: April 26, 2007
    Inventors: Emma Parmee, Ronald Kim, Rui Liang, Jiang Chang, Elizabeth Rouse, Kevin Chapman
  • Pyrazole derivatives, compositions containing such compounds and methods of use
    Publication number: 20070088070
    Abstract: Pyrazoles having a naphthyl group attached are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.
    Type: Application
    Filed: October 19, 2006
    Publication date: April 19, 2007
    Inventors: Emma Parmee, Yusheng Xiong, Jian Guo, Linda Brockunier
  • Acyl indoles, compositions containing such compounds and methods of use
    Publication number: 20070088071
    Abstract: The present invention relates to substituted indoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus and related conditions.
    Type: Application
    Filed: October 13, 2006
    Publication date: April 19, 2007
    Inventors: Ronald Kim, Amy Bittner, Christopher Sinz, Emma Parmee
  • Cyclohexylglycine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
    Publication number: 20070021477
    Abstract: The present invention is directed to novel cyclohexylglycine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
    Type: Application
    Filed: June 10, 2004
    Publication date: January 25, 2007
    Inventors: Scott Edmondson, Anthony Mastracchio, Emma Parmee
  • Fused indoles as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
    Publication number: 20060281796
    Abstract: The present invention is directed to fused indole derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
    Type: Application
    Filed: June 2, 2004
    Publication date: December 14, 2006
    Inventors: Scott Edmondson, Anthony Mastracchio, Emma Parmee
  • Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
    Publication number: 20060270679
    Abstract: The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
    Type: Application
    Filed: August 7, 2006
    Publication date: November 30, 2006
    Inventors: Scott Edmondson, Michael Fisher, Dooseop Kim, Malcolm Maccoss, Emma Parmee, Ann Weber, Jinyou Xu
  • Dipeptidyl peptidase inhibitors for the treatment of diabetes
    Patent number: 7098239
    Abstract: Compounds having Formula I, including pharmaceutically acceptable salts and prodrugs thereof: (Formula I) are inhibitors of the dipep tidyl peptidase-IV enzyme (DP-IV), and are useful in the treatment of DP-IV mediated diseases and conditions, such as non-insulin dependent diabetes mellitus.
    Type: Grant
    Filed: June 19, 2002
    Date of Patent: August 29, 2006
    Assignee: Merck & Co., Inc
    Inventors: Scott D. Edmondson, Emma Parmee, Ann E. Weber, Jinyou Xu
  • Spirocyclic ureas, compositions containing such compounds and methods of use
    Publication number: 20060116366
    Abstract: The present invention relates to spirocyclic ureas, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
    Type: Application
    Filed: November 26, 2003
    Publication date: June 1, 2006
    Inventors: Emma Parmee, Fengqi Zhang, Dong-Ming Shen, John Stelmach
  • Substituted pyrazoles, compositions containing such compounds and methods of use
    Publication number: 20060084681
    Abstract: The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
    Type: Application
    Filed: January 23, 2004
    Publication date: April 20, 2006
    Inventors: Emma Parmee, Subharekha Raghavan, Teresa Beeson, Dong-Ming Shen
  • Pyrazole derivatives, compositions containing such compounds and methods of use
    Publication number: 20050272794
    Abstract: Pyrazoles having a naphthyl group attached are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.
    Type: Application
    Filed: June 3, 2005
    Publication date: December 8, 2005
    Inventors: Emma Parmee, Yusheng Xiong, Jian Guo, Rui Liang, Linda Brockunier
  • Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
    Publication number: 20050107390
    Abstract: The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
    Type: Application
    Filed: March 21, 2003
    Publication date: May 19, 2005
    Inventors: Linda Brockunier, Joseph Duffy, Dooseop Kim, Emma Parmee, Ann Weber
  • Dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
    Publication number: 20040236102
    Abstract: Compounds having Formula I, including pharmaceutically acceptable salts and prodrugs thereof. (I) are inhibitors of the dipeptidyl peptidase-IV enzyme (DP-IV), and are useful in the treatment of DP-IV mediated diseases and conditions, such as non-insulin dependent diabetes mellitus.
    Type: Application
    Filed: December 18, 2003
    Publication date: November 25, 2004
    Inventors: Linda Brockunier, Emma Parmee, Ann E Weber
  • Dipeptidyl peptidase inhibitors for the treatment of diabetes
    Publication number: 20040176428
    Abstract: Compounds having Formula I, including pharmaceutically acceptable salts and prodrugs thereof: (Formula I) are inhibitors of the dipep tidyl peptidase-IV enzyme (DP-IV), and are useful in the treatment of DP-IV mediated diseases and conditions, such as non-insulin dependent diabetes mellitus.
    Type: Application
    Filed: December 18, 2003
    Publication date: September 9, 2004
    Inventors: Scott D. Edmondson, Emma Parmee, Ann E. Weber, Jinyou Xu