Patents by Inventor Emma Vickerstaffe

Emma Vickerstaffe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic heterocyclic compounds as FGFR inhibitors
    Patent number: 8895745
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: November 25, 2014
    Assignee: Astex Therapeutics Limited
    Inventors: Valerio Berdini, Gilbert Ebai Besong, Owen Callaghan, Maria Grazia Carr, Miles Stuart Congreve, Adrian Liam Gill, Charlotte Mary Griffiths-Jones, Andrew Madin, Christopher William Murray, Rajdeep Kaur Nijjar, Michael Alistair O'Brien, Andrew Pike, Gordon Saxty, Richard David Taylor, Emma Vickerstaffe
  • Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors
    Patent number: 8859582
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of formula (I): wherein R1, q, A, B, X1, X2, X3, X4, X5 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: October 14, 2014
    Assignee: Astex Therapeutics Limited
    Inventors: Gordon Saxty, Valerio Berdini, Christopher William Murray, Charlotte Mary Griffiths-Jones, Emma Vickerstaffe, Gilbert Ebai Besong
  • Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors
    Patent number: 8859583
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of formula (I): wherein R1, A, X1, X2, X3, X4, X5 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: October 14, 2014
    Assignee: Astex Therapeutics Limited
    Inventors: Gordon Saxty, Valerio Berdini, Christopher William Murray, Charlotte Mary Griffiths-Jones, Emma Vickerstaffe, Gilbert Ebai Besong, Maria Grazia Carr
  • Imidazopyridine derivatives as inhibitors of receptor tyrosine kinases
    Patent number: 8796244
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: August 5, 2014
    Assignee: Astex Therapeutics Ltd
    Inventors: Valerio Berdini, Maria Grazia Carr, Miles Stuart Congreve, Martyn Frederickson, Charlotte Mary Griffiths-Jones, Christopher Charles Frederick Hamlett, Andrew Madin, Christopher William Murray, Rajdeep Kaur Benning, Gordon Saxty, Emma Vickerstaffe, Andrew James Woodhead, Steven John Woodhead, Eddy Jean Edgard Freyne, Tom Cornelis Hortense Govaerts, Patrick René Angibaud, Marian Williams
  • Imidazo[1,2-a]pyridine compounds for use in treating cancer
    Patent number: 8513276
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: August 20, 2013
    Assignee: Astex Therapeutics Limited
    Inventors: Valerio Berdini, Gilbert Ebai Besong, Owen Callaghan, Maria Grazia Carr, Miles Stuart Congreve, Adrian Liam Gill, Charlotte Mary Griffiths-Jones, Andrew Madin, Christopher William Murray, Rajdeep Kaur Nijjar, Michael Alistair O'Brien, Andrew Pike, Gordon Saxty, Richard David Taylor, Emma Vickerstaffe
  • IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES
    Publication number: 20120208791
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Application
    Filed: June 12, 2009
    Publication date: August 16, 2012
    Applicant: ASTEX THERAPEUTICS LIMITED
    Inventors: Valerio Berdini, Maria Grazia Carr, Miles Stuart Congreve, Martyn Frederickson, Charlotte Mary Griffiths-Jones, Christopher Charles Frederick Hamlett, Andrew Madin, Christopher William Murray, Rajdeep Kaur Benning, Gordon Saxty, Emma Vickerstaffe, Brian John Williams, Marian Williams, Andrew James Woodhead, Steven John Woodhead, Eddy Jean Edgard Freyne, Tom Cornelis Hortense Govaerts, Patrick René Angibaud
  • BICYCLIC HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS
    Publication number: 20120035152
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of formula (I): wherein R1, q, A, B, X1, X2, X3, X4, X5 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Application
    Filed: October 18, 2011
    Publication date: February 9, 2012
    Applicant: ASTEX THERAPEUTICS LIMITED
    Inventors: Gordon SAXTY, Valerio BERDINI, Christopher William MURRAY, Charlotte Mary GRIFFITHS-JONES, Emma VICKERSTAFFE, Gilbert Ebai BESONG
  • BICYCLIC HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS
    Publication number: 20120035153
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of formula (I): wherein R1, A, X1, X2, X3, X4, X5 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Application
    Filed: October 18, 2011
    Publication date: February 9, 2012
    Applicant: ASTEX THERAPEUTICS LIMITED
    Inventors: Gordon SAXTY, Valerio BERDINI, Christopher William MURRAY, Charlotte Mary GRIFFITHS-JONES, Emma VICKERSTAFFE, Gilbert Ebai BESONG, Maria Grazia CARR
  • Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors
    Patent number: 8076354
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of formula (I): wherein R1, A, X1, X2, X3, X4, X5 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: December 13, 2011
    Assignee: Astex Therapeutics Limited
    Inventors: Gordon Saxty, Valerio Berdini, Christopher William Murray, Charlotte Mary Griffiths-Jones, Emma Vickerstaffe, Gilbert Ebai Besong, Maria Grazia Carr
  • Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors
    Patent number: 8071614
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of formula (I): wherein R1, q, A, B, X1, X2, X3, X4, X5 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: December 6, 2011
    Assignee: Astex Therapeutics Limited
    Inventors: Gordon Saxty, Valerio Berdini, Christopher William Murray, Charlotte Mary Griffiths-Jones, Emma Vickerstaffe, Gilbert Ebai Besong
  • BICYCLIC HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS
    Publication number: 20100331296
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of formula (I): wherein R1, A, X1, X2, X3, X4, X5 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Application
    Filed: October 10, 2008
    Publication date: December 30, 2010
    Applicant: Astex Therapeutics Limited
    Inventors: Gordon Saxty, Valerio Berdini, Christopher William Murray, Charlotte Mary Griffiths-Jones, Emma Vickerstaffe, Gilbert Ebai Besong, Maria Grazia Carr
  • BICYCLIC HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS
    Publication number: 20100286113
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of formula (I): wherein R1, q, A, B, X1, X2, X3, X4, X5 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Application
    Filed: October 10, 2008
    Publication date: November 11, 2010
    Applicant: ASTEX THERAPEUTICS LIMITED
    Inventors: Gordon Saxty, Valerio Berdini, Christopher William Murray, Charlotte Mary Griffiths-Jones, Emma Vickerstaffe, Gilbert Ebai Besong
  • Bicyclic Heterocyclic Compounds as FGFR Inhibitors
    Publication number: 20100120761
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
    Type: Application
    Filed: December 21, 2007
    Publication date: May 13, 2010
    Applicant: Astex Therapeutics Limited
    Inventors: Valerio Berdini, Gilbert Ebai Besong, Owen Callaghan, Maria Grazia Carr, MIles Stuart Congreve, Adrian Liam Gill, Charlotte Mary Griffiths-Jones, Andrew Madin, Christopher William Murray, Rajdeep Kaur Nijjar, Michael Alistair O'Brien, Andrew Pike, Gordon Saxty, Richard David Taylor, Emma Vickerstaffe
  • Compounds
    Publication number: 20100093718
    Abstract: The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR.
    Type: Application
    Filed: December 21, 2007
    Publication date: April 15, 2010
    Inventors: Valerio Berdini, Gilbert Ebai Besong, Owen Callaghan, Maria Grazia Carr, Miles Stuart Congreve, Adrian Liam Gill, Charlotte Mary Griffiths-Jones, Andrew Madin, Christopher William Murray, Rajdeep Kaur Nijjar, Michael Alistair O'Brien, Andrew Pike, Gordon Saxty, Richard David Taylor, Emma Vickerstaffe