Patents by Inventor Emmanouil D. Karagiannis

Emmanouil D. Karagiannis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210130882
    Abstract: The present invention provides compositions and methods that allow lipid membranes to be imaged optically at nanoscale resolution via a lipid-optimized form of expansion microscopy, also referred to as membrane expansion microscopy (mExM). mExM, via a post-expansion antibody labeling protocol, enables protein-lipid relationships to be imaged in organelles such as mitochondria, the endoplasmic reticulum, the nuclear membrane, and the Golgi apparatus. mExM may be of use in a variety of biological contexts, including the study of cell-cell interactions, intracellular transport, and neural connectomics.
    Type: Application
    Filed: November 4, 2020
    Publication date: May 6, 2021
    Inventors: Edward Stuart Boyden, Jeong Seuk Kang, Emmanouil D. Karagiannis
  • Patent number: 9187539
    Abstract: Compositions and methods that are useful for modulating blood vessel formation, as well as methods that provide for the systematic and efficient identification of angiogenesis modulators are described. As discussed in more detail below, a systematic computational methodology based on bioinformatics was used to identify novel peptide modulators of angiogenesis that have been characterized in vitro and/or in vivo.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: November 17, 2015
    Assignee: The Johns Hopkins University
    Inventors: Aleksander S. Popel, Emmanouil D. Karagiannis
  • Patent number: 9187544
    Abstract: Compositions and methods that are useful for modulating blood vessel formation, as well as methods that provide for the systematic and efficient identification of angiogenesis modulators, are described. As described in more detail below, a systematic computational methodology based on bioinformatics was used to identify novel peptide modulators of angiogenesis that have been characterized in vitro and/or in vivo.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: November 17, 2015
    Assignee: The Johns Hopkins University
    Inventors: Aleksander S. Popel, Emmanouil D. Karagiannis
  • Publication number: 20140100164
    Abstract: The invention generally features compositions and methods that are useful for modulating blood vessel formation, as well as methods that provide for the systematic and efficient identification of angiogenesis modulators. As described in more detail below, a systematic computational methodology based on bioinformatics was used to identify novel peptide modulators of angiogenesis that have been characterized in vitro and/or in vivo.
    Type: Application
    Filed: August 8, 2013
    Publication date: April 10, 2014
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Aleksander S. Popel, Emmanouil D. Karagiannis
  • Publication number: 20140045757
    Abstract: Compositions and methods that are useful for modulating blood vessel formation, as well as methods that provide for the systematic and efficient identification of angiogenesis modulators are described. As discussed in more detail below, a systematic computational methodology based on bioinformatics was used to identify novel peptide modulators of angiogenesis that have been characterized in vitro and/or in vivo.
    Type: Application
    Filed: August 23, 2013
    Publication date: February 13, 2014
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Aleksander S. Popel, Emmanouil D. Karagiannis
  • Patent number: 8557772
    Abstract: Compositions and methods that are useful for modulating blood vessel formation, as well as methods that provide for the systematic and efficient identification of angiogenesis modulators are described. As discussed in more detail below, a systematic computational methodology based on bioinformatics was used to identify novel peptide modulators of angiogenesis that have been characterized in vitro and/or in vivo.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: October 15, 2013
    Assignee: The Johns Hopkins University
    Inventors: Aleksander S. Popel, Emmanouil D. Karagiannis
  • Patent number: 8507434
    Abstract: Compositions and methods that are useful for modulating blood vessel formation, as well as methods that provide for the systematic and efficient identification of angiogenesis modulators are described. As discussed in more detail below, a systematic computational methodology based on bioinformatics was used to identify novel peptide modulators of angiogenesis that have been characterized in vitro and/or in vivo.
    Type: Grant
    Filed: January 3, 2008
    Date of Patent: August 13, 2013
    Assignee: The Johns Hopkins University
    Inventors: Aleksander S. Popel, Emmanouil D. Karagiannis
  • Publication number: 20120232012
    Abstract: The invention generally features compositions and methods that are useful for modulating blood vessel formation, as well as methods that provide for the systematic and efficient identification of angiogenesis modulators. As described in more detail below, a systematic computational methodology based on bioinformatics was used to identify novel peptide modulators of angiogenesis that have been characterized in vitro and/or in vivo.
    Type: Application
    Filed: February 8, 2012
    Publication date: September 13, 2012
    Applicant: The Johns Hopkins University
    Inventors: Aleksander S. Popel, Emmanouil D. Karagiannis
  • Publication number: 20110028395
    Abstract: The invention generally features compositions and methods that are useful for modulating blood vessel formation, as well as methods that provide for the systematic and efficient identification of angiogenesis modulators. As described in more detail below, a systematic computational methodology based on bioinformatics was used to identify novel peptide modulators of angiogenesis that have been characterized in vitro and/or in vivo.
    Type: Application
    Filed: January 3, 2008
    Publication date: February 3, 2011
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Aleksander S. Popel, Emmanouil D. Karagiannis
  • Publication number: 20100144641
    Abstract: The invention generally features compositions and methods that are useful for modulating blood vessel formation, as well as methods that provide for the systematic and efficient identification of angiogenesis modulators. As described in more detail below, a systematic computational methodology based on bioinformatics was used to identify novel peptide modulators of angiogenesis that have been characterized in vitro and/or in vivo.
    Type: Application
    Filed: September 12, 2006
    Publication date: June 10, 2010
    Inventors: Aleksander S. Popel, Emmanouil D. Karagiannis