Abstract: The present invention is directed to, inter alia, composition and methods for genome editing. Specifically, a non-naturally occurring OMNI-79 nuclease variant having a wild-type OMNI-79 protein sequence (SEQ ID NO: 1) comprising an amino acid substitution in at least one of the following positions: I14. S1005, and E1050.

Abstract: The present disclosure relates to an additive manufacturing (AM) process for making a three-dimensional (3D) object, using a powdered polymer material (M) comprising at least one semi-crystalline polymer or copolymer (P), in particular to a 3D object obtainable by laser sintering from this powdered polymer material (M).

Abstract: The invention relates to a system and methods for providing conditional access to indoor location information in a system comprising a mobile device (320), a positioning webservice (310) and an authorization authority (360), the method comprising: the mobile device (320) performing the steps of: transmitting license information to the authorization authority (360) and transmitting a request for indoor location information to the positioning webservice, the request comprising a request-location-estimate corresponding to a location estimate of the mobile device (320) at the time of making the request, the authorization authority (360) performing the steps of: receiving the license information, verifying whether the license information authorizes access to indoor location information by the mobile device (320), issuing a secure proof, verifiable by the positioning webservice (310) upon successful verification, the secure proof indicating that the license information authorizes access to indoor location informati

Abstract: Method of detecting a change in a lighting system comprising a plurality of devices each comprising a luminaire and/or a sensor, wherein each respective one of the devices has a respective location recorded in a commissioning database in association with data reported by the respective device; the method comprising: identifying a subset of said devices located within a predetermined spatial demarcation; automatically monitoring a respective value of a characteristic of each of the devices in said subset, thereby forming a data cluster comprising the values of said characteristic for the subset; automatically detecting that one of one of the devices in the subset has been moved by detecting a shift in one of the cluster values relative to the rest of the values in the data cluster; and in response to said detection, automatically outputting an indication that the commissioning database is likely to require updating to reflect said change.

Abstract: The invention relates to a system and methods for providing conditional access to indoor location information in a system comprising a mobile device (320), a positioning webservice (310) and an authorization authority (360), the method comprising: the mobile device (320) performing the steps of: transmitting license information to the authorization authority (360) and transmitting a request for indoor location information to the positioning webservice, the request comprising a request-location-estimate corresponding to a location estimate of the mobile device (320) at the time of making the request, the authorization authority (360) performing the steps of: receiving the license information, verifying whether the license information authorizes access to indoor location information by the mobile device (320), issuing a secure proof, verifiable by the positioning webservice (310) upon successful verification, the secure proof indicating that the license information authorizes access to indoor location informati

Abstract: The present invention is related to verifying an installed lighting system (300), in particular an Ethernet-based lighting system (300), without it being necessary to employ a designated lighting controller and without it being necessary to completely commission the installed lighting system (300). According to an aspect of the invention, this is achieved by providing a network switch (200) that comprises a plurality of ports for coupling luminaires (312A, 312B, 312C, 312D) and sensors and/or actuators (314A, 314B) of the lighting system (300) to the network switch (200); and by setting the network switch (200) such that a signal received at a first port (e.g. port 4) of the plurality of ports is only forwarded to pre-selected ports (e.g. ports 2,3,5,6 and 7) of the plurality of ports.

Abstract: The invention relates to a system and methods for providing conditional access to indoor location information in a system comprising a mobile device (320), a positioning webservice (310) and an authorization authority (360), the method comprising: the mobile device (320) performing the steps of: transmitting license information to the authorization authority (360) and transmitting a request for indoor location information to the positioning webservice, the request comprising a request-location-estimate corresponding to a location estimate of the mobile device (320) at the time of making the request, the authorization authority (360) performing the steps of: receiving the license information, verifying whether the license information authorizes access to indoor location information by the mobile device (320), issuing a secure proof, verifiable by the positioning webservice (310) upon successful verification, the secure proof indicating that the license information authorizes access to indoor location informati

Abstract: The present invention relates to a method for operating a communication apparatus in a network comprising a plurality of communication nodes, upon reception of a message at the communication apparatus, the communication apparatus starting a retransmission delay being selected at random from a retransmission delay interval, said retransmission delay interval being dependent on at least one of a status of the communication apparatus and a property of the received message, the communication apparatus monitors retransmissions of said message by other communication nodes during said retransmission delay and the communication apparatus transmitting a retransmission of said message at the expiry of said retransmission delay if a statistic based on the retransmissions of said message by other communication nodes is below a threshold.

Abstract: A method of performing analytics relating to energy management or space utilization in an environment of a lighting system, the method comprising: accessing a database of data reported by the devices, the data comprising values of one or more types of data reported by each respective one of the devices; depending on whether the analytics are to characterize location, device, or both, selecting between: i) using a designation of the location but not the ID as a selection criterion, ii) using a designation of the ID but not the location as a selection criterion, iii) using a designation of both the location and ID as a selection criterion, retrieving the values of data types reported by devices with the specified designation, and performing at least part of the analytics based thereon; and adapting one or more features of the environment and/or lighting system based on the performed analytics.

Abstract: Method of detecting a change in a lighting system comprising a plurality of devices each comprising a luminaire and/or a sensor, wherein each respective one of the devices has a respective location recorded in a commissioning database in association with data reported by the respective device; the method comprising: identifying a subset of said devices located within a predetermined spatial demarcation; automatically monitoring a respective value of a characteristic of each of the devices in said subset, thereby forming a data cluster comprising the values of said characteristic for the subset; automatically detecting that one of one of the devices in the subset has been moved by detecting a shift in one of the cluster values relative to the rest of the values in the data cluster; and in response to said detection, automatically outputting an indication that the commissioning database is likely to require updating to reflect said change.

Abstract: The present invention is related to verifying an installed lighting system (300), in particular an Ethernet-based lighting system (300), without it being necessary to employ a designated lighting controller and without it being necessary to completely commission the installed lighting system (300). According to an aspect of the invention, this is achieved by providing a network switch (200) that comprises a plurality of ports for coupling luminaires (312A, 312B, 312C, 312D) and sensors and/or actuators (314A, 314B) of the lighting system (300) to the network switch (200); and by setting the network switch (200) such that a signal received at a first port (e.g. port 4) of the plurality of ports is only forwarded to pre-selected ports (e.g. ports 2,3,5,6 and 7) of the plurality of ports.

Abstract: The present invention is related to verifying an installed lighting system (300), in particular an Ethernet-based lighting system (300), without it being necessary to employ a designated lighting controller and allowing the automatic commissioning of the installed lighting system (300). According to an aspect of the invention, this is achieved by providing a network switch (200) that comprises a plurality of ports for coupling luminaires (312A, 312B, 312C, 312D) and sensors and or actuators (314A, 314B) of the lighting system (300) to the network switch (200); and by setting the network switch (200) such that a signal received at a first port (e.g. port 4) of the plurality of ports is only forwarded to pre-selected ports (e.g. ports 2,3,5,6 and 7) of the plurality of ports.

Abstract: A milling device is rotatable in one direction around a longitudinal center axis defining a forward direction and an opposite rearward direction, and includes a front part and a rear part. The front part has cutting edges, each having a longitudinal extension, and chip flutes, each having a longitudinal extension. The front part is made of a monolithic piece of ceramic. The rear part is configured to be fixed in a rotatable tool body or a rotatable chuck. The rear part is also made of a monolithic piece of cemented carbide. A front end surface of the rear part has a smaller area than a rear end surface of the front part. The front end surface of the rear part and a rear end surface of the front part are permanently bonded or brazed to each other by a joint.

Abstract: The present invention relates to a method and apparatus for controlling power distribution by a control system that only requires a broadcast medium between a controller (30) and appliances or loads (20-1 to 20-n) and information about the current total power consumption of the system to precisely reach a target consumption level in a stepwise, fast converging way without “seesaw” effects and with “fair distribution” of any power reduction.

Abstract: The present invention relates to a method for operating a communication apparatus in a network comprising a plurality of communication nodes, upon reception of a message at the communication apparatus, the communication apparatus starting a retransmission delay being selected at random from a retransmission delay interval, said retransmission delay interval being dependent on at least one of a status of the communication apparatus and a property of the received message, the communication apparatus monitors retransmissions of said message by other communication nodes during said retransmission delay and the communication apparatus transmitting a retransmission of said message at the expiry of said retransmission delay if a statistic based on the retransmissions of said message by other communication nodes is below a threshold.

Abstract: A configuration system (100) is provided arranged to configure a first set (112, 114, 116, 118, 117, 119) of wireless network devices to form a first stand-alone wireless network. A configuration device (140) is arranged to wirelessly connect with the first set of wireless network devices and to transfer the first configuration parameters to the first set of wireless network devices forming the first stand-alone wireless network. The first configuration parameters are selected to be compatible with a future connected wireless network if the first set of wireless network devices and a second set of wireless network devices are placed so that they may be connected to a same gateway device (129) forming a future connected wireless network.

Abstract: The invention relates to a system and methods for providing conditional access to indoor location information in a system comprising a mobile device (320), a positioning webservice (310) and an authorization authority (360), the method comprising: the mobile device (320) performing the steps of: transmitting license information to the authorization authority (360) and transmitting a request for indoor location information to the positioning webservice, the request comprising a request-location-estimate corresponding to a location estimate of the mobile device (320) at the time of making the request, the authorization authority (360) performing the steps of: receiving the license information, verifying whether the license information authorizes access to indoor location information by the mobile device (320), issuing a secure proof, verifiable by the positioning webservice (310) upon successful verification, the secure proof indicating that the license information authorizes access to indoor location informati

Abstract: A milling device is rotatable in one direction around a longitudinal center axis defining a forward direction and an opposite rearward direction, and includes a front part and a rear part. The front part has cutting edges, each having a longitudinal extension, and chip flutes, each having a longitudinal extension. The front part is made of a monolithic piece of ceramic. The rear part is configured to be fixed in a rotatable tool body or a rotatable chuck. The rear part is also made of a monolithic piece of cemented carbide. A front end surface of the rear part has a smaller area than a rear end surface of the front part. The front end surface of the rear part and a rear end surface of the front part are permanently bonded or brazed to each other by a joint.

Abstract: The present invention relates to an apparatus and method for interpreting control commands received from a control element, wherein the control element sends control commands indicating start of activation (e.g., press operation) and end of activation (e.g., release operation) separately. Two time thresholds provided by respective timers (T1, T2) are used at the controlled device (20), a lower time threshold for determining the short activation and a higher time threshold for determining the long activation; the difference between the two time thresholds indicates a “dead zone” of no control action.