Patents by Inventor Emmanuel Delamarche
Emmanuel Delamarche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100048428Abstract: Methods for screening and arranging microorganisms such as viruses in an array using subtractive contact printing are provided. In one embodiment, a method for forming an array of receptors for microorganisms comprises: patterning an array of structures on a first substrate to form a template on a surface of the first substrate; applying a receptor material to a face of a second substrate; and contacting the face of the second substrate with the template to remove a portion of the receptor material from the second substrate, thereby forming an array of receptors on the second substrate.Type: ApplicationFiled: August 21, 2008Publication date: February 25, 2010Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Sean R. Coyer, Emmanuel Delamarche, Daniel J. Solis
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Publication number: 20090318303Abstract: Disclosed herein is a system comprising a chip; a flow channel disposed in the chip; the flow channel being in communication with an entry port and an exit port; the flow channel being operative to permit the flow of a library from the entry port to the exit port; a substrate; the substrate being disposed upon the chip; the substrate being operative to act as an upper wall for the flow channel; and a receptor; the receptor being disposed on the substrate; the receptor being operative to interact with a component from the library.Type: ApplicationFiled: June 20, 2008Publication date: December 24, 2009Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Emmanuel Delamarche, Robert Lovchik, Daniel J. Solis
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Publication number: 20090318302Abstract: Disclosed herein is a microfluidic device comprising a chip; a flow channel being disposed in the chip; the flow channel being in communication with an entry port and an exit port; the flow channel being operative to permit the flow of a library from the entry port to the exit port; a substrate; the substrate being disposed upon the chip; the substrate being operative to act as an upper wall for the flow channels; and a plurality of receptors; the plurality of receptors being disposed on the substrate; the plurality of receptors being operative to interact with an element from the library.Type: ApplicationFiled: June 20, 2008Publication date: December 24, 2009Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Emmanuel Delamarche, Robert Lovchik, Daniel J. Solis
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Publication number: 20090298161Abstract: A biosensor comprising surface treated with a method for producing a monolayer of molecules on a surface, the method comprising loading a stamp with seed molecules, transferring seed molecules from the stamp to the surface, wherein transferring comprises transferring a fraction of the seed molecules loaded on the stamp to the surface and adsorbing the seed molecules to the stamp and adsorbing the seed molecules to the surface, the adsorption of the seed molecules to the stamp being stronger than the adsorption of the seed molecules to the surface, self-completing amplification of the seed molecules via an amplifying reaction to produce the monolayer on a flat surface, wherein self-completing amplification comprises producing a homogeneous area, wherein the homogeneous area comprises a monolayer of molecules on the surface, and wherein the monolayer of molecules on the surface has no diffusive component that can relocate and destroy amplification accuracy.Type: ApplicationFiled: August 13, 2009Publication date: December 3, 2009Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Sergey Amontov, Emmanuel Delamarche, Bruno Michel
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Publication number: 20090135471Abstract: A display element having circuitry adapted to at least partially electrochemically dissolve a first layer by means of supplying an electrical current through the first layer. The first layer separates a first reservoir filled with a liquid from a second reservoir. By dissolving the first layer at least partially, at least a portion of the liquid can flow from the first to the second reservoir. Consequently, the display element transitions from a first to a second optical state.Type: ApplicationFiled: November 14, 2008Publication date: May 28, 2009Applicant: International Business Machines CorporationInventors: Emmanuel Delamarche, Erich M. Ruetsche
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Patent number: 7491272Abstract: A microfluidic device for applying a liquid to a surface comprises a chamber for carrying the liquid, an aperture in the chamber for communicating liquid from the chamber to the surface via a conduit having outer sides of limited wetability to the liquid. This device provides a solution for confining liquids to defined areas of a surface without involving physical seals and additionally permits moving the device and confined liquid on the surface.Type: GrantFiled: November 13, 2003Date of Patent: February 17, 2009Assignee: International Business Machines CorporationInventors: Emmanuel Delamarche, David Juncker, Heinz Schmid
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Publication number: 20090038493Abstract: A method for transferring a pattern from an elastic stamp to a substrate in the presence of a third medium is described. A proximity contact is achieved between the stamp and the substrate. A layer of the third medium between the stamp and the substrate is controlled to a predetermined thickness. Stamps for carrying out this method are also described.Type: ApplicationFiled: October 10, 2008Publication date: February 12, 2009Inventors: Alexander Bietsch, Emmanuel Delamarche, Bruno Michel, Heinz Schmid, Heiko Wolf
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Patent number: 7434512Abstract: A method for transferring a pattern from an elastic stamp to a substrate in the presence of a third medium is described. A proximity contact is achieved between the stamp and the substrate. A layer of the third medium between the stamp and the substrate is controlled to a predetermined thickness. Stamps for carrying out this method are also described.Type: GrantFiled: August 28, 2003Date of Patent: October 14, 2008Assignee: International Business Machines CorporationInventors: Alexander Bietsch, Emmanuel Delamarche, Bruno Michel, Heinz Schmid, Heiko Wolf
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Publication number: 20080245771Abstract: A method for processing a surface involves depositing at least one class of enzymes (2) onto the surface (1); introducing at least a reactant (3) into an environment of the surface (1), and causing interaction between the enzymes (2) and the reactant (3), thereby to cause processing of a region of the surface (1), the processed region of the surface (1) being defined with respect to a region thereof that is proximate (4) to where the enzymes (3) have been deposited.Type: ApplicationFiled: December 18, 2007Publication date: October 9, 2008Applicant: International Business Machines CorporationInventors: Emmanuel Delamarche, Matthias Geissler
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Publication number: 20080057570Abstract: An apparatus, system, and method for determining the osmolarity of a fluid. The apparatus includes at least one micro-fluidic circuit and at least one electrical circuit disposed in communication with the at least one micro-fluidic circuit for determining a property of a fluid contained within the at least one micro-fluidic circuit.Type: ApplicationFiled: August 29, 2006Publication date: March 6, 2008Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Govindarajan Natarajan, Emmanuel Delamarche, Eric A. Eckberg, James N. Humenik, Kathleen A. McGroddy-Goetz, Scott Partington, Christopher F. Perrera, Marco G. Trivella, Timothy M. Wiwel
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Publication number: 20080057569Abstract: An apparatus, system and method for determining the osmolarity of a fluid. The system includes an apparatus having: a chip with a substantially planar top surface; a first circuit portion and a second circuit portion, each having a plurality of redundant electrically conductive lines disposed on the top surface; and a gap disposed between the first circuit portion and the second circuit portion, wherein a circuit is created when a fluid sample bridges the gap and connects the first circuit portion and the second circuit portion.Type: ApplicationFiled: August 29, 2006Publication date: March 6, 2008Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Govindarajan Natarajan, Emmanuel Delamarche, Eric A. Eckberg, James N. Humenik, Kathleen A. McGroddy-Goetz, Scott Partington, Christopher F Perrera, Marco G. Trivella, Timothy M. Wiwel
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Patent number: 7329111Abstract: A device for flowing a liquid on a surface comprises: a flow path. A first port supplies the liquid to one end of the flow path and applies a first port pressure for retaining the liquid when the flow path is remote from the surface. A second port receives the liquid from the other end of the flow path and applies a second port pressure such that the difference between the first and second negative port pressures is oriented to promote flow of the liquid from the first port to the second port via the flow path in response to the flow path being located proximal to the surface and the liquid in the device contacting the surface. The first and second port pressures are such that the liquid is drawn towards at least the second port in response to withdrawal of the flow path from the surface. Such devices may employ microfluidic technology and find application in surface patterning.Type: GrantFiled: November 13, 2003Date of Patent: February 12, 2008Assignee: International Business Machines CorporationInventors: Emmanuel Delamarche, David Juncker, Bruno Michel, Heinz Schmid
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Publication number: 20080003572Abstract: A capillary system for performing surface assays comprising a capillary pump containing at least two zones having different capillary pressures for obtaining controlled flow rate of liquids. The different pressure zones may be created by various means such as by creating posts in the walls of the capillary pump, by having different sized capillary of the different zones, by changing the wetting properties, by defining friction at the walls of the pump or by combinations of any of the above. The capillary system finds use in various surface assays and can be programmed for defining the volume and rate of liquid flowing through the test sites. A microfluidic chip containing assembly of programmed capillary systems for performing need based specific assays and modifications thereof.Type: ApplicationFiled: June 30, 2006Publication date: January 3, 2008Inventors: Emmanuel Delamarche, Heinz Schmid, David Juncker
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Publication number: 20080000536Abstract: A device for flowing a liquid on a surface comprises: a flow path. A first port supplies the liquid to one end of the flow path and applies a first port pressure for retaining the liquid when the flow path is remote from the surface. A second port receives the liquid from the other end of the flow path and applies a second port pressure such that the difference between the first and second negative port pressures is oriented to promote flow of the liquid from the first port to the second port via the flow path in response to the flow path being located proximal to the surface and the liquid in the device contacting the surface. The first and second port pressures are such that the liquid is drawn towards at least the second port in response to withdrawal of the flow path from the surface. Such devices may employ microfluidic technology and find application in surface patterning.Type: ApplicationFiled: August 9, 2007Publication date: January 3, 2008Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Emmanuel Delamarche, David Juncker, Bruno Michel, Heinz Schmid
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Publication number: 20070015153Abstract: A method for producing a monolayer of molecules on a surface comprises: loading a stamp with seed molecules; transferring seed molecules from the stamp to the surface; and, amplifying the seed molecules via an amplifying reaction to produce the monolayer. The method permit generation of complete monolayers from incomplete or sparse monolayers initially printed on the surface.Type: ApplicationFiled: November 13, 2003Publication date: January 18, 2007Inventors: Sergey Amontov, Emmanuel Delamarche, Bruno Michel
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Publication number: 20060286560Abstract: A method for producing a monolayer of molecules on a surface is described. The method includes loading a stamp with seed molecules, transferring seed molecules from the stamp to the surface, and amplifying the seed molecules via an amplifying reaction to produce the monolayer. This method permits generation of complete monolayers from incomplete or sparse monolayers initially printed on the surface.Type: ApplicationFiled: June 16, 2005Publication date: December 21, 2006Applicant: International Business Machines CorporationInventors: Sergey Amontov, Emmanuel Delamarche, Bruno Michel
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Publication number: 20060127579Abstract: A microfluidic device for applying a liquid to a surface comprises a chamber for carrying the liquid, an aperture in the chamber for communicating liquid from the chamber to the surface via a conduit having outer sides of limited wettability to the liquid. This device provides a solution for confining liquids to defined areas of a surface without involving physical seals and additionally permits moving the device and confined liquid on the surface.Type: ApplicationFiled: November 13, 2003Publication date: June 15, 2006Inventors: Emmanuel Delamarche, David Juncker, Heinz Schmid
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Publication number: 20060096477Abstract: A method for transferring a pattern from an elastic stamp to a substrate in the presence of a third medium is described. A proximity contact is achieved between the stamp and the substrate. A layer of the third medium between the stamp and the substrate is controlled to a predetermined thickness. Stamps for carrying out this method are also described.Type: ApplicationFiled: August 28, 2003Publication date: May 11, 2006Inventors: Alexander Bietsch, Emmanuel Delamarche, Bruno Michel, Heinz Schmid, Heiko Wolf
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Patent number: 7041232Abstract: A wet etching system for selectively patterning substrates having regions covered with self-assembled monolayers (SAM) thereby controlling the etch profile. The system contains a) a liquid etching solution; and b) at least one additive to the liquid etching solution having a higher affinity to the regions of the substrate covered with the SAMs than to the other regions of the substrate. Also provided is a method of selectively patterning substrates having regions covered with self-assembled monolayers (SAMs), thereby controlling the etch profile, the method consisting of the steps of a) providing a liquid etching solution; b) adding at least one additive to said etching solution having a higher affinity to the regions of the substrate covered with the SAMs than to the other regions of the substrate; and c) etching said substrate with said liquid etching solution containing at least one additive.Type: GrantFiled: February 22, 2002Date of Patent: May 9, 2006Assignee: International Business Machines CorporationInventors: Alexander Bietsch, Emmanuel Delamarche, Bruno Michel, Heinz Schmid, Matthias Geisler
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Publication number: 20060093697Abstract: A device for flowing a liquid on a surface comprises: a flow path. A first port supplies the liquid to one end of the flow path and applies a first port pressure for retaining the liquid when the flow path is remote from the surface. A second port receives the liquid from the other end of the flow path and applies a second port pressure such that the difference between the first and second negative port pressures is oriented to promote flow of the liquid from the first port to the second port via the flow path in response to the flow path being located proximal to the surface and the liquid in the device contacting the surface. The first and second port pressures are such that the liquid is drawn towards at least the second port in response to withdrawal of the flow path from the surface. Such devices may employ microfluidic technology and find application in surface patterning.Type: ApplicationFiled: November 13, 2003Publication date: May 4, 2006Inventors: Emmanuel Delamarche, David Juncker, Bruno Michel, Heinz Schmid