Patents by Inventor Emmanuel E. Baetge

Emmanuel E. Baetge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatocyte lineage cells
    Patent number: 8574905
    Abstract: Disclosed herein are methods for producing liver precursor cells as well as hepatocyte cells form pluripotent and/or multipotent cells. Also disclosed herein are methods of enriching isolating and/or purifying liver precursor cells and/or hepatocyte cells. Further disclosed are compositions comprising cell cultures and cell populations that are enriched for liver precursor cells or hepatocyte cells.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: November 5, 2013
    Assignee: ViaCyte, Inc.
    Inventors: Kevin D'Amour, Emmanuel E. Baetge
  • Encapsulation of pancreatic cells derived from human pluripotent stem cells
    Patent number: 8425928
    Abstract: The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: April 23, 2013
    Assignee: ViaCyte, Inc.
    Inventors: Laura Martinson, Chad Green, Evert Kroon, Alan Agulnick, Olivia Kelly, Emmanuel E. Baetge
  • METHODS FOR IDENTIFYING FACTORS FOR DIFFERENTIATING DEFINITIVE ENDODERM
    Publication number: 20120276624
    Abstract: Disclosed herein are methods of identifying one or more differentiation factors that are useful for differentiating cells in a cell population comprising definitive endoderm cells into cells which are capable of forming tissues and/or organs that are derived from the gut tube.
    Type: Application
    Filed: July 9, 2012
    Publication date: November 1, 2012
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • Encapsulation of pancreatic cells derived from human pluripotent stem cells
    Patent number: 8278106
    Abstract: The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: October 2, 2012
    Assignee: Viacyte, Inc.
    Inventors: Laura Martinson, Chad Green, Evert Kroon, Alan Agulnick, Olivia Kelly, Emmanuel E. Baetge
  • Methods for identifying factors for differentiating definitive endoderm
    Patent number: 8216836
    Abstract: Disclosed herein are methods of identifying one or more differentiation factors that are useful for differentiating cells in a cell population comprising definitive endoderm cells into cells which are capable of forming tissues and/or organs that are derived from the gut tube.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: July 10, 2012
    Assignee: Viacyte, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • Endocrine precursor cells, pancreatic hormone-expressing cells and methods of production
    Patent number: 8129182
    Abstract: Disclosed herein are cell cultures and enriched cell populations of endocrine precursor cells, immature pancreatic hormone-expressing cells and mature pancreatic hormone-expressing cells. Also disclosed herein are methods of producing such cell cultures and cell populations.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: March 6, 2012
    Assignee: Viacyte, Inc.
    Inventors: Kevin A. D'Amour, Anne Bang, Emmanuel E. Baetge
  • ENDOCRINE PRECURSOR CELLS, PANCREATIC HORMONE-EXPRESSING CELLS AND METHODS OF PRODUCTION
    Publication number: 20120034692
    Abstract: Disclosed herein are cell cultures and enriched cell populations of endocrine precursor cells, immature pancreatic hormone-expressing cells and mature pancreatic hormone-expressing cells. Also disclosed herein are methods of producing such cell cultures and cell populations.
    Type: Application
    Filed: October 17, 2011
    Publication date: February 9, 2012
    Inventors: Kevin A. D'Amour, Anne Bang, Emmanuel E. Baetge
  • PREPRIMITIVE STREAK AND MESENDODERM CELLS
    Publication number: 20120021511
    Abstract: This disclosure relates to compositions comprising human preprimitive streak cells and/or human mesendoderm cells as well as methods for their production. Additionally, disclosed herein are methods of identifying factors useful in the further differentiation of preprimitive streak and mesendoderm cell types.
    Type: Application
    Filed: July 25, 2011
    Publication date: January 26, 2012
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Evert Kroon, Emmanuel E. Baetge
  • HEPATOCYTE LINEAGE CELLS
    Publication number: 20110294211
    Abstract: Disclosed herein are methods for producing liver precursor cells as well as hepatocyte cells form pluripotent and/or multipotent cells. Also disclosed herein are methods of enriching isolating and/or purifying liver precursor cells and/or hepatocyte cells. Further disclosed are compositions comprising cell cultures and cell populations that are enriched for liver precursor cells or hepatocyte cells.
    Type: Application
    Filed: August 2, 2011
    Publication date: December 1, 2011
    Inventors: Kevin D'Amour, Emmanuel E. Baetge
  • ENCAPSULATION OF PANCREATIC CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS
    Publication number: 20110280915
    Abstract: The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation.
    Type: Application
    Filed: July 22, 2011
    Publication date: November 17, 2011
    Inventors: Laura Martinson, Chad Green, Evert Kroon, Alan Agulnick, Olivia Kelly, Emmanuel E. Baetge
  • Hepatocyte lineage cells
    Patent number: 7989204
    Abstract: Disclosed herein are methods for producing liver precursor cells as well as hepatocyte cells form pluripotent and/or multipotent cells. Also disclosed herein are methods of enriching isolating and/or purifying liver precursor cells and/or hepatocyte cells. Further disclosed are compositions comprising cell cultures and cell populations that are enriched for liver precursor cells or hepatocyte cells.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: August 2, 2011
    Assignee: Viacyte, Inc.
    Inventors: Kevin D'Amour, Emmanuel E. Baetge
  • Preprimitive streak and mesendoderm cells
    Patent number: 7985585
    Abstract: This disclosure relates to compositions comprising human preprimitive streak cells and/or human mesendoderm cells as well as methods for their production. Additionally, disclosed herein are methods of identifying factors useful in the further differentiation of preprimitive streak and mesendoderm cell types.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: July 26, 2011
    Assignee: Viacyte, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Emmanuel E. Baetge
  • PDX1-EXPRESSING DORSAL AND VENTRAL FOREGUT ENDODERM
    Publication number: 20100233755
    Abstract: Disclosed herein are cell cultures comprising dorsal and/or ventral PDX1-positive foregut endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified dorsal and/or ventral PDX1-positive foregut endoderm cells as well as methods for enriching, isolating and purifying dorsal and/or ventral PDX1-positive foregut endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of dorsal and/or ventral PDX1-positive foregut endoderm cells, are also disclosed.
    Type: Application
    Filed: March 22, 2010
    Publication date: September 16, 2010
    Inventors: KEVIN ALLEN D'AMOUR, ALAN D. AGULNICK, SUSAN ELIAZER, EMMANUEL E. BAETGE
  • DEFINITIVE ENDODERM
    Publication number: 20100151568
    Abstract: Disclosed herein are cell cultures comprising definitive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified definitive endoderm cells as well as methods for enriching, isolating and purifying definitive endoderm cells from other cell types.
    Type: Application
    Filed: February 22, 2010
    Publication date: June 17, 2010
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Emmanuel E. Baetge
  • ENCAPSULATION OF PANCREATIC CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS
    Publication number: 20100124564
    Abstract: The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation.
    Type: Application
    Filed: November 13, 2009
    Publication date: May 20, 2010
    Inventors: Laura Martinson, Chad Green, Evert Kroon, Alan Agulnick, Olivia Kelly, Emmanuel E. Baetge
  • Definitive endoderm
    Patent number: 7704738
    Abstract: Disclosed herein are cell cultures comprising definitive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified definitive endoderm cells as well as methods for enriching, isolating and purifying definitive endoderm cells from other cell types.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: April 27, 2010
    Assignee: Cythera, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Emmanuel E. Baetge
  • EXPANSION OF DEFINITIVE ENDODERM CELLS
    Publication number: 20100041150
    Abstract: Disclosed herein are cell cultures comprising expanded definitive endoderm cells as well as methods for expanding definitive endoderm cells in culture.
    Type: Application
    Filed: October 20, 2009
    Publication date: February 18, 2010
    Inventors: Olivia Kelly, Emmanuel E. Baetge, Melissa Carpenter
  • METHODS FOR IDENTIFYING FACTORS FOR DIFFERENTIATING DEFINITIVE ENDODERM
    Publication number: 20090311703
    Abstract: Disclosed herein are methods of identifying one or more differentiation factors that are useful for differentiating cells in a cell population comprising definitive endoderm cells into cells which are capable of forming tissues and/or organs that are derived from the gut tube.
    Type: Application
    Filed: June 2, 2009
    Publication date: December 17, 2009
    Inventors: KEVIN ALLEN D'AMOUR, ALAN D. AGULNICK, SUSAN ELIAZER, EMMANUEL E. BAETGE
  • HEPATOCYTE LINEAGE CELLS
    Publication number: 20090298170
    Abstract: Disclosed herein are methods for producing liver precursor cells as well as hepatocyte cells form pluripotent and/or multipotent cells. Also disclosed herein are methods of enriching isolating and/or purifying liver precursor cells and/or hepatocyte cells. Further disclosed are compositions comprising cell cultures and cell populations that are enriched for liver precursor cells or hepatocyte cells.
    Type: Application
    Filed: April 27, 2007
    Publication date: December 3, 2009
    Inventors: Kevin D'Amour, Emmanuel E. Baetge
  • Expansion of definitive endoderm cells
    Patent number: 7625753
    Abstract: Disclosed herein are cell cultures comprising expanded definitive endoderm cells as well as methods for expanding definitive endoderm cells in culture.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: December 1, 2009
    Assignee: Cythera, Inc.
    Inventors: Olivia Kelly, Emmanuel E. Baetge, Melissa Carpenter