Patents by Inventor Emmanuel Hubert

Emmanuel Hubert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thetrahydroquinolines derivatives as bromodomain inhibitors
    Patent number: 8580957
    Abstract: Tetrahydroquinoline compounds of formula (I) or a salt thereof, pharmaceutical compositions containing such compounds and their use in therapy, in particular in the treatment of diseases or conditions for which a bromodomain inhibitor is indicted.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: November 12, 2013
    Assignee: GlaxoSmithKline LLC
    Inventors: Emmanuel Hubert Demont, Romain Luc Marie Gosmini
  • Tetrahydroquinoline Derivatives And Their Pharmaceutical Use
    Publication number: 20120208798
    Abstract: Tetrahydroquinoline compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
    Type: Application
    Filed: November 3, 2010
    Publication date: August 16, 2012
    Inventors: Emmanuel Hubert Demont, Neil Stuart Garton, Romain Luc Marie Gosmini, Thomas George Christopher Hayhow, Jonathan Seal, David Matthew Wilson, Michael David Woodrow
  • Thetrahydroquinolines Derivatives As Bromodomain Inhibitors
    Publication number: 20120208814
    Abstract: Tetrahydroquinoline compounds of formula (I) or a salt thereof, pharmaceutical compositions containing such compounds and their use in therapy, in particular in the treatment of diseases or conditions for which a bromodomain inhibitor is indicted.
    Type: Application
    Filed: November 3, 2010
    Publication date: August 16, 2012
    Inventors: Emmanuel Hubert Demont, Romain Luc Marie Gosmini
  • Oxadiazole derivatives active on sphingosine-1-phosphate (S1P)
    Patent number: 8222245
    Abstract: The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: July 17, 2012
    Assignee: Glaxo Group Limited
    Inventors: Emmanuel Hubert Demont, Jag Paul Heer, John Skidmore, Ian David Wall, Jason Witherington, Thomas Daniel Heightman, David Nigel Hurst, Christopher Norbert Johnson
  • S1P1 AGONISTS COMPRISING A BICYCLIC N-CONTAINING RING
    Publication number: 20120101083
    Abstract: The present invention relates to novel compounds of formula (I) having S1P1 agonist activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
    Type: Application
    Filed: June 17, 2010
    Publication date: April 26, 2012
    Applicant: GLAXO GROUP LIMITED
    Inventors: James Matthew Bailey, Rino Antonio Bit, Emmanuel Hubert Demont, Lee Andrew Harrison, Katherine Louise Jones, Christian Alan Paul Smethurst, Jason Witherington
  • THIADIAZOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF DISORDERS MEDIATED BY S1P1 RECEPTORS
    Publication number: 20120101086
    Abstract: The present invention relates to novel compounds having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
    Type: Application
    Filed: June 17, 2010
    Publication date: April 26, 2012
    Applicant: GLAXO GROUP LIMITED
    Inventors: James Matthew Bailey, John Alexander Brown, Emmanuel Hubert Demont, Lee Andrew Harrison, Gail Astra Lorraine Seal, Christian Alan Paul Smethurst, Jason Witherington
  • THIAZOLE OR THIADIZALOE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS
    Publication number: 20120094979
    Abstract: Thiazole or thiadizaloe derivatives of formula (I) or pharmaceutical salts thereof having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their uses in the treatment of various disorders mediated by S1P1 receptor are disclosed.
    Type: Application
    Filed: June 17, 2010
    Publication date: April 19, 2012
    Applicant: Glaxo Wellcome House
    Inventors: James Matthew Bailey, Emmanuel Hubert Demont, Xichen Lin, Feng Ren, Christian Alan Paul Smethurst
  • Pyrazole Derivatives as P2X7 Modulators
    Publication number: 20110046137
    Abstract: The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof: The pyrazole derivatives of formula (I) or salts thereof modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor (P2X7 receptor antagonists). The invention also relates to the use of such compounds or salts, or pharmaceutical compositions thereof, in the treatment or prevention of disorders/diseases mediated by the P2X7 receptor, for example pain, inflammation or a neurodegenerative disease.
    Type: Application
    Filed: May 8, 2008
    Publication date: February 24, 2011
    Inventors: Paul John Beswick, Laura Jane Chambers, Iain Patrick Chessell, David John Davies, Emmanuel Hubert Demont, Robert James Gleave, David George Hubert Livermore, Pamela Joan Theobald, Mythily Vimal, Daryl Simon Walter
  • OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP)
    Publication number: 20100273771
    Abstract: The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
    Type: Application
    Filed: December 19, 2008
    Publication date: October 28, 2010
    Inventors: Emmanuel Hubert Demont, Jag Paul Heer, John Skidmore, Ian David Wall, Jason Witherington, Thomas Daniel Heightman, David Nigel Hurst, Christopher Norbert Johnson
  • N-(Phenylmethyl)-2-(1H-Pyrazol-4-yl) Acetamide Derivatives as P2X7 Antagonists for the Treatment of Pain, Inflammation and Neurodegeneration
    Publication number: 20090149524
    Abstract: The present invention relates to novel pyrazole derivatives of formula (I) which bind to the P2X7 receptor and are capable of interfering with the effects of ATP at the P2X7 receptor: and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.
    Type: Application
    Filed: June 5, 2007
    Publication date: June 11, 2009
    Inventors: Paul John Beswick, Laura J. Chambers, David John Davies, David Kenneth Dean, Emmanuel Hubert Demont, Susan Roomans, Daryl Simon Walter
  • Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases
    Publication number: 20080255358
    Abstract: Disclosed are imidazopyridine compounds having the formula:
    Type: Application
    Filed: March 22, 2006
    Publication date: October 16, 2008
    Inventors: Mark James Bamford, Emmanuel Hubert Demont, Richard Leonard Elliott, Gerard Martin Paul Giblin, Antoinette Naylor, Terence Aaron Panchal, Jason Witherington