Patents by Inventor Emmanuel Macedo

Emmanuel Macedo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220098538
    Abstract: The present invention relates to a method and system for aseptic material transfer from a storage container to a biore-actor. More precisely the invention relates to a method and system for aseptically transferring dry material, such as microcarriers for cell cultivation, to a bioreactor, comprising transferring microcarriers from a first container housing said microcarriers to a bioreactor for cell cultivation via r transfer tubing connecting the first container to the bioreactor, wherein the transfer is accomplished with pressurized air or gas supplied to the container.
    Type: Application
    Filed: December 13, 2021
    Publication date: March 31, 2022
    Inventors: Bjorn Johan Lundgren, Emmanuel Macedo, Ann-Christin Magnusson, Lena Maria Sandberg
  • Patent number: 11225636
    Abstract: The present invention relates to a method and system for aseptic material transfer from a storage container to a bioreactor. More precisely the invention relates to a method and system for aseptically transferring dry material, such as microcarriers for cell cultivation, to a bioreactor, comprising transferring microcarriers from a first container housing said microcarriers to a bioreactor for cell cultivation via r transfer tubing connecting the first container to the bioreactor, wherein the transfer is accomplished with pressurized air or gas supplied to the container.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: January 18, 2022
    Assignee: Cytiva Sweden AB
    Inventors: Bjorn Johan Lundgren, Emmanuel Macedo, Ann-Christin Magnusson, Lena Maria Sandberg
  • Publication number: 20180291326
    Abstract: The present invention relates to a method and system for aseptic material transfer from a storage container to a bioreactor. More precisely the invention relates to a method and system for aseptically transferring dry material, such as microcarriers for cell cultivation, to a bioreactor, comprising transferring microcarriers from a first container housing said microcarriers to a bioreactor for cell cultivation via r transfer tubing connecting the first container to the bioreactor, wherein the transfer is accomplished with pressurized air or gas supplied to the container.
    Type: Application
    Filed: May 16, 2016
    Publication date: October 11, 2018
    Inventors: Bjorn Johan Lundgren, Emmanuel Macedo, Ann-Christin Magnusson, Lena Maria Sandberg
  • Patent number: 8268915
    Abstract: The present invention relates to a liquid mixture comprising a first polymer, which is a poly(acid), a second polymer, which is a poly(ether), and at least one salt, wherein the molecular weight of the poly(acid) is in the range of 1000-100,000 Da. The second polymer is selected to be capable of forming immiscible aqueous phases in the presence of the poly(acid) and salt. The poly(acid) may be selected from the group consisting of poly(acrylic acid) and poly(methacrylic acid), and the second synthetic polymer may comprise ethylene oxide. The invention may be used for separation of biomolecules, cells or particles.
    Type: Grant
    Filed: June 16, 2008
    Date of Patent: September 18, 2012
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Hans O. Johansson, James Van Alstine, Rolf Hjorth, Karol Lacki, Emmanuel Macedo, Gunnar Malmquist, Jamil Shanagar
  • Publication number: 20100179252
    Abstract: The present invention relates to a liquid mixture comprising a first polymer, which is a poly(acid), a second polymer, which is a poly(ether), and at least one salt, wherein the molecular weight of the poly(acid) is in the range of 1000-100,000 Da. The second polymer is selected to be capable of forming immiscible aqueous phases in the presence of the poly(acid) and salt. The poly(acid) may be selected from the group consisting of poly(acrylic acid) and poly(methacrylic acid), and the second synthetic polymer may comprise ethylene oxide. The invention may be used for separation of biomolecules, cells or particles.
    Type: Application
    Filed: June 16, 2008
    Publication date: July 15, 2010
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Hans O. Johansson, James Van Alstine, Rolf Hjorth, Karol Lacki, Emmanuel Macedo, Gunnar Malmquist, Jamil Shanagar
  • Publication number: 20100174052
    Abstract: The present invention relates to a process of isolating one or more target compounds, wherein the clarification of feed is performed using partitioning in a multiphase system comprising a first polymer, which is a synthetic poly(acid), a second synthetic polymer, which is a poly(ether), and at least one salt, which clarification is followed by at least one step of affinity chromatography. The molecular weight of the poly(acid) may be in the range of 1000-100,000 Da. The target compound is preferably a biomolecule, such as a monoclonal antibody.
    Type: Application
    Filed: June 16, 2008
    Publication date: July 8, 2010
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Rolf Hjorth, Karol Lacki, Emmanuel Macedo, Gunnar Malmquist, Jamil Shanagar, James Van Alstine