Abstract: A personalized insertion guide for the mini-invasive insertion of a device through a target bone, includes a guide platform securable to a fixation bone, presenting an internal bone contact surface being a matching negative of the fixation bone surface in order to allow one single precise positioning of it. At least one insertion channel is configured to receive the device. At least one bone fixation structure for secures the guide platform to the fixation bone. The guide platform is designed by means of a presurgical modelling of the fixation bone, based on a geometrical analysis of its surface. The guide enables, once positioned on the fixation bone, to set the origin of a referential with regards to a biological target element inside the body. The guide platform includes a first part and second part extending in two different plans.