Patents by Inventor Emmanuel Payen

Emmanuel Payen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL HUMAN ERYTHROID PROGENITOR CELL LINE HIGHLY PERMISSIVE TO B19 INFECTION AND USES THEREOF
    Publication number: 20240101958
    Abstract: The present invention concerns a novel human erythroid progenitor cell line, wherein at least 90% of the cells are CD36+ CD44?CD71+; and wherein the cells:—do not express the gene encoding the receptor of Granulocyte-macrophage colony-stimulating factor (GM-CSF-R gene) or express GM-CSF-R gene at a lower level than the cells of human UT-7/Epo-S1 cell line; and—express the gene encoding the receptor of erythropoietin (Epo-R gene). The present invention also concerns the uses thereof for producing, detecting, or quantifying parvovims B19. The present invention allows the use of the cell lines for 1) a highly sensitive B19 infectious particles detection, and, 2) the efficient production of infectious B19 particles.
    Type: Application
    Filed: December 13, 2021
    Publication date: March 28, 2024
    Inventors: Zahra KADRI, Stany CHRETIEN, Emmanuel PAYEN, Bruno YOU, Celine DUCLOUX
  • Method of Selecting Genetically Modified Hematopoietic Stem Cells
    Publication number: 20200208112
    Abstract: The present invention relates to a method of selecting genetically modified hematopoietic stem cells using the combination of a positive selection marker and a MDR1 inhibitor.
    Type: Application
    Filed: May 22, 2018
    Publication date: July 2, 2020
    Applicants: Commissariat a l'Energie Atomique et aux Energies Alternatives, Institut National de la Sante et de la Recherche Medicale, Universite Paris Sud
    Inventors: Emmanuel Payen, Kanit Bhukhai, Philippe Leboulch, Julian Down
  • Gene therapy methods
    Patent number: 10280435
    Abstract: The present invention generally provides improved gene therapy vectors, cell-based compositions, and methods of using the same in methods of gene therapy. The present invention further provides improved gene therapy compositions for expanding hematopoietic cells and related methods for treatment of diseases, disorders, and conditions of the hematopoietic system such as thalassemias and anemias.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: May 7, 2019
    Assignee: bluebird bio, Inc.
    Inventors: Olivier Negre, Emmanuel Payen, Philippe Leboulch, Yves Beuzard
  • GENE THERAPY METHODS
    Publication number: 20180201952
    Abstract: The present invention generally provides improved gene therapy vectors, cell-based compositions, and methods of using the same in methods of gene therapy. The present invention further provides improved gene therapy compositions for expanding hematopoietic cells and related methods for treatment of diseases, disorders, and conditions of the hematopoietic system such as thalassemias and anemias.
    Type: Application
    Filed: October 9, 2017
    Publication date: July 19, 2018
    Applicant: bluebird bio, Inc.
    Inventors: Olivier NEGRE, Emmanuel PAYEN, Philippe LEBOULCH, Yves BEUZARD
  • Gene therapy methods
    Patent number: 9783822
    Abstract: The present invention generally provides improved gene therapy vectors, cell-based compositions, and methods of using the same in methods of gene therapy. The present invention further provides improved gene therapy compositions for expanding hematopoietic cells and related methods for treatment of diseases, disorders, and conditions of the hematopoietic system such as thalassemias and anemias.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: October 10, 2017
    Assignee: bluebird Bio, Inc.
    Inventors: Oliver Negre, Emmanuel Payen, Philippe Leboulch, Yves Beuzard
  • GENE THERAPY METHODS
    Publication number: 20150203868
    Abstract: The present invention generally provides improved gene therapy vectors, cell-based compositions, and methods of using the same in methods of gene therapy. The present invention further provides improved gene therapy compositions for expanding hematopoietic cells and related methods for treatment of diseases, disorders, and conditions of the hematopoietic system such as thalassemias and anemias.
    Type: Application
    Filed: September 23, 2011
    Publication date: July 23, 2015
    Applicant: Bluebird BIO, Inc.
    Inventors: Oliver Negre, Emmanuel Payen, Philippe Leboulch, Yves Beuzard
  • Device for Preparing and Filling a Tooth Endodontic Cavity
    Publication number: 20080227053
    Abstract: A catheterization device for preparing and filling a tooth endodontic cavity includes at least one root canal tool connected to a drive head. The tool is movable and has a base movably driven by the drive head about the reference axis of the base. A totally or partially eroded, filiform and elastic working part freely extends from the base and has an axis shifted in a parallel position with respect to the reference axis of the base.
    Type: Application
    Filed: October 27, 2006
    Publication date: September 18, 2008
    Applicant: MICRO MEGA INTERNATIONAL MANUFACTURES
    Inventor: Emmanuel Payen De La Caranderie