Abstract: Novel compounds having formula (I) and methods of using these compounds to treat diseases, conditions, and disorders are described.

Abstract: Systems, apparatuses, and methods are directed toward determining emotional states of a subject. For example, the systems, apparatuses, and methods determine one or more previous characteristics of a pupil of an eye based on image data from eye tracking sensors, determine one or more current characteristics of the pupil based on image data from the eye tracking sensors, where the one or more current characteristics include one or more of a current position of the pupil or a current size of the pupil, track movements, based on image data from the eye tracking sensors, in a position of the pupil and changes in a size of the pupil over a time period, automatically predict an emotional state based on a comparison between the one or more previous characteristics and the one or more current characteristics, the tracked movements and the tracked changes in the size and adjust a parameter of one or more hardware devices based on the predicted emotional state.

Abstract: The present invention relates to a pharmaceutical composition comprising a compound of the avermectin family, preferably ivermectin, in a pharmaceutically acceptable carrier, for use in the treatment and/or prevention of hand eczema.

Abstract: A commodity-measuring device for autonomously selecting a commodity supplier among a plurality of commodity suppliers being specified within a blockchain distributed database is provided. A microcontroller unit is configured to provide commodity consumption data to the transaction manager. A storage is configured to store a private key, and a communication module is configured to retrieve a commodity supplier file stored in the blockchain distributed database, and the commodity supplier file includes parameters of a commodity supplier and a program. A transaction manager is configured to determine autonomously, based on the commodity consumption data and parameters in the commodity supplier file, whether to select the commodity supplier; and if the determination is positive, the transaction manager is configured to, using the private key, send a transaction to the blockchain distributed database calling a function in the program to associate the commodity supplier file with the identifier.

Abstract: Systems, apparatuses, and methods are directed toward determining emotional states of a subject. For example, the systems, apparatuses, and methods determine one or more previous characteristics of a pupil of an eye based on image data from eye tracking sensors, determine one or more current characteristics of the pupil based on image data from the eye tracking sensors, where the one or more current characteristics include one or more of a current position of the pupil or a current size of the pupil, track movements, based on image data from the eye tracking sensors, in a position of the pupil and changes in a size of the pupil over a time period, automatically predict an emotional state based on a comparison between the one or more previous characteristics and the one or more current characteristics, the tracked movements and the tracked changes in the size and adjust a parameter of one or more hardware devices based on the predicted emotional state.

Abstract: A method for tracking components of equipment. The method includes generating a first record in a component tracking data store of a component tracking system for storing original constituent component identification information that specifies original constituent components of the equipment, and a second record in the component tracking data store of the component tracking system for storing replacement component identification information that specifies a replacement component that replaces a component of the original constituent components of the equipment. The method further includes receiving a request for a current listing of components in the equipment and locating records in the component tracking data store of the component tracking system associated with the equipment.

Abstract: This document describes systems, methods, devices, and other techniques for managing healthcare records. In some implementations, a computing system is provided that includes an electronic ledger, a first program module, and a second program module. The electronic ledger can store entries of medical record management events invoked by participants in a distributed computing network. The first program module can be assigned to an account of a first user on the distributed computing network and can identify (i) medical records of the first user and (ii) accounts of users other than the first user that are authorized to access the medical records of the first user. The second program module can be assigned to an account of a second user on the distributed computing network and can call the first program module to request access to a set of one or more of the medical records of the first user.

Abstract: The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid ? toxicity. More specifically, the present invention relates to novel combinatorial therapies of Alzheimer's disease, Alzheimer's disease related disorders, amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on baclofen and acamprosate combination.

Abstract: The present invention relates to a pharmaceutical composition comprising a compound of the avermectin family, preferably ivermectin, in a pharmaceutically acceptable carrier, for use in the treatment and/or prevention of hand eczema.

Abstract: The present invention relates to compositions and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid ? toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorders, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury.

Abstract: A method of treating and/or preventing atopic dermatitis is described. The method includes use of a compound of the avermectin family, possibly ivermectin, or a compound of the milbemycin family in a pharmaceutically acceptable carrier.

Abstract: A seismic protective structure (100) for forming part of a board partition (190) and for limiting damage to the board partition (190) when a given level of seismic stress is appearing is described. The seismic protective structure (100) comprises at least one board (101) and support elements (102, 103) for positioning the board adjacent a neighboring wall and linking the board to the remainder of the board partition wall. The seismic protective structure (100) is adapted for, when a given level of seismic stress is appearing, intentionally causing damage of the at least one board (101) thereby releasing pressure from the remainder of the board partition(190).

Abstract: The present invention relates to compositions and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid ? toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorders, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury.

Abstract: A seismic protective structure (100) for forming part of a board partition (190) and for limiting damage to the board partition (190) when a given level of seismic stress is appearing is described. The seismic protective structure (100) comprises at least one board (101) and support elements (102, 103) for positioning the board adjacent a neighboring wall and linking the board to the remainder of the board partition wall. The seismic protective structure (100) is adapted for, when a given level of seismic stress is appearing, intentionally causing damage of the at least one board (101) thereby releasing pressure from the remainder of the board partition (190).

Abstract: The invention concerns a method of making a payment transaction by a customer including steps of receiving, by a mobile device (402) of the customer, merchant data; transmitting, by the mobile device to a remote server (408), a payment transaction request including the merchant data; determining, by the remote server; the identity of the customer based on the request and the identity of the merchant based on the data; and implementing the payment transaction between bank accounts of the customer and the merchant.

Abstract: A method of accessing electronic content received by a mobile device includes: determining a current location of the mobile device; comparing the current location with a zone within which an instance of electronic content may be accessed; when the result of the comparison indicates that the mobile device is located within the zone, accessing by the mobile device the instance of electronic content and providing at least part of the instance of electronic content for display on the mobile device; determining a new current location of the mobile device while the instance of electronic content is being accessed; and checking that the new current location of the mobile device is with the zone. If the mobile device is no longer within the zone, access by the mobile device to the instance of electronic content is terminated.

Abstract: This document generally describes systems, methods, devices, and other techniques for using distributed ledgers, such as a blockchain database, to facilitate secure distribution and use of 3D model files to 3D printers over a computing network. A 3D printer controller may access an electronic ledger that identifies a plurality of 3D model files that have been made available for distribution. A particular 3D model file and a secret key may be obtained by the printer, where the 3D model file is encrypted based on the secret key. The secret key can be decrypted using a private key associated with the computing device that corresponds to the public key. After decrypting the secret key, the particular 3D model file can be decrypted using the secret key, and after decrypting the particular 3D model file, the particular 3D model file can be executed on the printer to print a physical 3D object.

Abstract: This document generally describes techniques for using a distributed ledger to implement a framework for the validation and distribution of virus signatures, which may be used by antivirus engines on computing devices to detect and remove malware. Some implementations can include accessing, by a computing system, data that identifies a plurality of virus signatures. A signature score associated with a first virus signature can be identified that is determined based on a number of signature authorities that have submitted or endorsed the first virus signature. The computing system may determine whether the first virus signature is valid based on whether the signature score satisfies a threshold score. In response to determining that the first virus signature is valid, the first virus signature can be used by the computing system to perform virus scans of one or more files maintained by the computing system.

Abstract: A method for tracking components of equipment. The method includes generating a first record in a component tracking data store of a component tracking system for storing original constituent component identification information that specifies original constituent components of the equipment, and a second record in the component tracking data store of the component tracking system for storing replacement component identification information that specifies a replacement component that replaces a component of the original constituent components of the equipment. The method further includes receiving a request for a current listing of components in the equipment and locating records in the component tracking data store of the component tracking system associated with the equipment.

Abstract: The present invention relates to compositions and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid ? toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorders, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury.