Abstract: A method is disclosed comprising obtaining or acquiring chemical or other non-mass spectrometric data from one or more regions of a target using a chemical sensor. The chemical or other non-mass spectrometric data may be used to determine one or more regions of interest of the target. An ambient ionisation ion source may then be used to generate aerosol, smoke or vapour from one or more regions of the target.

Abstract: A method is disclosed comprising providing a biological sample on a swab, directing a spray of charged droplets onto a surface of the swab in order to generate a plurality of analyte ions, and analysing the analyte ions.

Abstract: A method of ion imaging is disclosed that includes automatically sampling a plurality of different locations on a sample using a front device which is arranged and adapted to generate aerosol, smoke or vapour from the sample. Mass spectral data and/or ion mobility data corresponding to each location is obtained and the obtained mass spectral data and/or ion mobility data is used to construct, train or improved a sample classification model.

Abstract: A method is disclosed comprising obtaining physical or other non-mass spectrometric data from one or more regions of a target using a probe. The physical or other non-mass spectrometric data may be used to determine one or more regions of interest of the target. An ambient ionisation ion source may then used to generate an aerosol, smoke or vapour from one or more regions of the target.

Abstract: A method is disclosed comprising obtaining or acquiring image or other data from one or more regions of a target using an imaging sensor. The image or other data may then be used to determine one or more regions of interest of the target. An ambient ionisation ion source may then be used to generate aerosol, smoke or vapour from one or more regions of the target.

Abstract: An apparatus for performing ambient ionisation mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped, coil-shaped, helical or spiral-shaped collision assembly; and a first device arranged and adapted to direct analyte, smoke, fumes, liquid, gas, surgical smoke, aerosol or vapour onto said collision assembly.

Abstract: A method, system, and method for developing the system, for producing hydrocarbons from a plurality of hydrocarbon containing reservoirs is described. The system includes at least one conventional hydrocarbon reservoir and at least one natural gas hydrate reservoir. The system also includes a production facility, including water separation apparatus, which is in fluid communication with the at least one hydrocarbon reservoir and the at least one natural gas hydrate reservoir. The production facility can separate hydrocarbons and water concurrently received from the first conventional hydrocarbon and the second natural gas hydrate reservoirs. The at least one hydrocarbon reservoir and the at least one hydrate reservoir can be concurrently developed. Or else, the at least one hydrate reservoir can be developed later in time and then fluidly connected to the production facility.

Abstract: The present invention is directed to using depressurization methods to create mobile fluid zones for producing fluids from a Class 3 hydrate reservoirs through a well. Aspects of the present invention include a two stage method wherein the first stage includes producing fluid from a hydrate interval within the Class 3 hydrate reservoir through a well at a constant pressure and forming an interface, and the second stage includes producing fluid through the interface at a constant mass rate and heating the well.

Abstract: The present invention is directed to using depressurization methods to create mobile fluid zones for producing fluids from a Class 3 hydrate reservoirs through a well. Aspects of the present invention include a two stage method wherein, the first stage includes producing fluid from a hydrate interval within the Class 3 hydrate reservoir through a well at a constant pressure and forming an interface, arid the second stage includes producing fluid through the interface at a constant mass rate and heating the well.