Patents by Inventor Enbal Ziv
Enbal Ziv has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11433025Abstract: A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.Type: GrantFiled: August 17, 2018Date of Patent: September 6, 2022Assignee: Vyne Therapeutics Inc.Inventors: Dov Tamarkin, Helena Shifrin, Rita Keynan, Enbal Ziv, Tal Berman, David Schuz, Elana Gazal
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Patent number: 11219631Abstract: A substantially surface active agent-free foamable composition which includes short-chain alcohol, water, polymer, fatty alcohol or fatty acid or a combination of fatty alcohol and fatty acid and propellant. A substantially surface active agent-free foamable composition which includes, water, polymer, fatty alcohol or fatty acid and propellant. A method of treatment using a substantially surface active agent-free foamable compositions.Type: GrantFiled: August 22, 2018Date of Patent: January 11, 2022Assignee: Vyne Pharmaceuticals Inc.Inventors: Dov Tamarkin, Enbal Ziv, Yohan Hazot, David Schuz
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Patent number: 11033491Abstract: The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.Type: GrantFiled: October 16, 2020Date of Patent: June 15, 2021Assignee: Vyne Therapeutics Inc.Inventors: Dov Tamarkin, Doron Friedman, Tal Berman, Enbal Ziv, David Schuz
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Publication number: 20210038517Abstract: The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.Type: ApplicationFiled: October 16, 2020Publication date: February 11, 2021Inventors: Dov Tamarkin, Doron Friedman, Tal Berman, Enbal Ziv, David Schuz
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Patent number: 10821077Abstract: The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.Type: GrantFiled: February 23, 2018Date of Patent: November 3, 2020Assignee: Foamix Pharmaceuticals Ltd.Inventors: Dov Tamarkin, Doron Friedman, Tal Berman, Enbal Ziv, David Schuz
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Publication number: 20200078298Abstract: The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.Type: ApplicationFiled: April 17, 2019Publication date: March 12, 2020Inventors: Dov Tamarkin, Doron Friedman, Tal Berman, Enbal Ziv, David Schuz
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Publication number: 20200022912Abstract: A substantially surface active agent-free and substantially polymeric agent-free foamable composition which includes short-chain alcohol, water, fatty alcohol or fatty acid or a combination of fatty alcohol and fatty acid and propellant. A substantially surface active agent-free and substantially polymeric agent-free foamable composition which includes water, fatty alcohol or fatty acid and propellant. A method of treatment using a substantially surface active agent-free and substantially polymeric agent-free foamable composition.Type: ApplicationFiled: May 29, 2019Publication date: January 23, 2020Inventors: Dov Tamarkin, Enbal Ziv, Yohan Hazot, David Schuz
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Publication number: 20190247310Abstract: The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.Type: ApplicationFiled: February 23, 2018Publication date: August 15, 2019Applicant: Foamix Pharmaceuticals Ltd.Inventors: Dov Tamarkin, Doron Friedman, Tal Berman, Enbal Ziv, David Schuz
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Patent number: 10350166Abstract: A substantially surface active agent-free and substantially polymeric agent-free foamable composition is disclosed, which includes short-chain alcohol, water, fatty alcohol or fatty acid or a combination of fatty alcohol and fatty acid and propellant. Also disclosed is a method of treatment by applying the substantially surface active agent-free and substantially polymeric agent-free foamable composition.Type: GrantFiled: June 8, 2015Date of Patent: July 16, 2019Assignee: FOAMIX PHARMACEUTICALS LTD.Inventors: Dov Tamarkin, Enbal Ziv, Yohan Hazot, David Schuz
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Patent number: 10322085Abstract: The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.Type: GrantFiled: November 13, 2018Date of Patent: June 18, 2019Assignee: FOAMIX PHARMACEUTICALS LTD.Inventors: Dov Tamarkin, Doron Friedman, Tal Berman, Enbal Ziv, David Schuz
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Publication number: 20190091149Abstract: A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.Type: ApplicationFiled: August 17, 2018Publication date: March 28, 2019Inventors: Dov Tamarkin, Helena Shifrin, Rita Keynan, Enbal Ziv, Tal Berman, David Schuz, Elana Gazal
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Publication number: 20190076356Abstract: The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.Type: ApplicationFiled: November 13, 2018Publication date: March 14, 2019Inventors: Dov Tamarkin, Doron Friedman, Tal Berman, Enbal Ziv, David Schuz
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Publication number: 20190054106Abstract: A substantially surface active agent-free foamable composition which includes short-chain alcohol, water, polymer, fatty alcohol or fatty acid or a combination of fatty alcohol and fatty acid and propellant. A substantially surface active agent-free foamable composition which includes, water, polymer, fatty alcohol or fatty acid and propellant. A method of treatment using a substantially surface active agent-free foamable compositions.Type: ApplicationFiled: August 22, 2018Publication date: February 21, 2019Inventors: Dov TAMARKIN, Enbal ZIV, Yohan HAZOT, David SCHUZ
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Publication number: 20190022001Abstract: The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.Type: ApplicationFiled: February 23, 2018Publication date: January 24, 2019Applicant: Foamix Pharmaceuticals Ltd.Inventors: Dov Tamarkin, Doron Friedman, Tal Berman, Enbal Ziv, David Schuz
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Patent number: 10092588Abstract: A substantially surface active agent-free foamable composition which includes short-chain alcohol, water, polymer, fatty alcohol or fatty acid or a combination of fatty alcohol and fatty acid and propellant. A substantially surface active agent-free foamable composition which includes, water, polymer, fatty alcohol or fatty acid and propellant. A method of treatment using a substantially surface active agent-free foamable compositions.Type: GrantFiled: January 9, 2017Date of Patent: October 9, 2018Assignee: Foamix Pharmaceuticals Ltd.Inventors: Dov Tamarkin, Enbal Ziv, Yohan Hazot, David Schuz
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Publication number: 20170216334Abstract: A substantially surface active agent-free foamable composition which includes short-chain alcohol, water, polymer, fatty alcohol or fatty acid or a combination of fatty alcohol and fatty acid and propellant. A substantially surface active agent-free foamable composition which includes, water, polymer, fatty alcohol or fatty acid and propellant. A method of treatment using a substantially surface active agent-free foamable compositions.Type: ApplicationFiled: January 9, 2017Publication date: August 3, 2017Inventors: Dov Tamarkin, Enbal Ziv, Yohan Hazot, David Schuz
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Publication number: 20170181970Abstract: A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.Type: ApplicationFiled: November 11, 2016Publication date: June 29, 2017Inventors: Dov Tamarkin, Helena Shifrin, Rita Keynan, Enbal Ziv, Tal Berman, David Schuz, Elana Gazal
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Patent number: 9682021Abstract: The present invention relates to stable substantially non-aqueous, non-alcoholic, non-silicone, foamable carrier compositions comprising petrolatum or mixtures thereof, at least one foam agent, at least one propellant, and with and without the addition of an active agent. The formulations may contain a solvent substantially miscible therein. The present invention further provides a method of treating, alleviating or preventing a disorder of mammalian subject in need thereof, comprising administering the above-mentioned compositions to an afflicted target site of said mammalian subject.Type: GrantFiled: February 25, 2014Date of Patent: June 20, 2017Assignee: FOAMIX PHARMACEUTICALS LTD.Inventors: Dov Tamarkin, Doron Friedman, Enbal Ziv, Meir Eini, Tal Berman, Jorge Danziger, Rita Keynan, David Schuz
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Patent number: 9572775Abstract: A substantially surface active agent-free foamable composition which includes short-chain alcohol, water, polymer, fatty alcohol or fatty acid or a combination of fatty alcohol and fatty acid and propellant. A substantially surface active agent-free foamable composition which includes, water, polymer, fatty alcohol or fatty acid and propellant. A method of treatment using a substantially surface active agent-free foamable compositions.Type: GrantFiled: September 17, 2015Date of Patent: February 21, 2017Assignee: Foamix Pharmaceuticals Ltd.Inventors: Dov Tamarkin, Enbal Ziv, Yohan Hazot, David Schuz
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Patent number: 9549898Abstract: A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.Type: GrantFiled: October 2, 2014Date of Patent: January 24, 2017Assignee: Foamix Pharmaceuticals Ltd.Inventors: Dov Tamarkin, Helena Shifrin, Rita Keynan, Enbal Ziv, Tal Berman, David Schuz, Elana Gazal