Patents by Inventor Endri Karaj

Endri Karaj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ferroptosis-HDAC Inhibitor Hybrid Anticancer Agents
    Publication number: 20240109852
    Abstract: Hybrid molecules having pharmacophores of a ferrotoptosis inducer and an HDAC inhibitor, as well as ferroptosis inducers and HDAC inhibitors, and methods of making and using the same, are described.
    Type: Application
    Filed: August 28, 2023
    Publication date: April 4, 2024
    Applicant: The University of Toledo
    Inventors: Viranga Tillekeratne, Endri Karaj, Shaimaa Sindi, William Taylor
  • Imidazole-based anticancer agents and derivatives thereof, and methods of making and using same
    Patent number: 11098038
    Abstract: Imidazole-based anticancer agents and derivatives thereof, as well as methods of making and methods of using the same, are described. The imidazole-based anticancer agents are HDAC inhibitor compounds having a 1-(1H-imidazol-2-yl)ethan-1-one or 1-(1H-imidazol-2-yl)ethane-1-thione moiety.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: August 24, 2021
    Assignee: The University of Toledo
    Inventors: Viranga Tillekeratne, Ayad Al-Hamashi, Samkeliso Dlamini, Abdulateef Saeed S. Alqahtani, Endri Karaj
  • IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME
    Publication number: 20200385374
    Abstract: Imidazole-based anticancer agents and derivatives thereof, as well as methods of making and methods of using the same, are described. The imidazole-based anticancer agents are HDAC inhibitor compounds having a 1-(1H-imidazol-2-yl)ethan-1-one or 1-(1H-imidazol-2-yl)ethane-1-thione moiety.
    Type: Application
    Filed: August 17, 2018
    Publication date: December 10, 2020
    Applicant: The University of Toledo
    Inventors: Viranga Tillekeratne, Ayad Al-Hamashi, Samkeliso Dlamini, Abdulateef Saeed S. Alqahtani, Endri Karaj