Patents by Inventor Eng-Kiat Lim

Eng-Kiat Lim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLUCOSYLTRANSFERASES
    Publication number: 20100181035
    Abstract: We describe transgenic cells which are transformed with nucleic acid molecules which encode glucosyltransferase polypeptides involved in phenylpropanoid biosynthesis.
    Type: Application
    Filed: December 15, 2009
    Publication date: July 22, 2010
    Applicant: UNIVERSITY OF YORK
    Inventors: Dianna BOWLES, Rosamond JACKSON, Eng Kiat LIM, Fabian Vaistij
  • MONOTERPENOID MODIFYING ENZYMES
    Publication number: 20100143975
    Abstract: Monoterpenoid esters that have been modified to include a sugar pendant group are disclosed. Plant glycosyltransferase enzymes are provided that function to add a sugar, typically glucose, to monoterpenoids in a bioreactor for the production of glycosylated monoterpenoid esters, together with nucleic acid molecules encoding such enzymes and vectors and transgenic cells including such nucleic acid molecules.
    Type: Application
    Filed: November 20, 2007
    Publication date: June 10, 2010
    Applicant: THE UNIVERSITY OF YORK
    Inventors: Lorenzo Caputi, Eng-Kiat Lim, Dianna Joy Bowles
  • SESQUITERPENOID MODIFYING ENZYMES
    Publication number: 20100132073
    Abstract: We describe glycosyltransferase polypeptides that modify sesquiterpenoids and including pharmaceutical compositions comprising glycosylated sesquiterpenoids; methods to treat diseases, in particular cancer, bacterial and fungal infections and also flavourings and scents comprising glycosylated sesquiterpenoids.
    Type: Application
    Filed: November 26, 2007
    Publication date: May 27, 2010
    Applicant: THE UNIVERSITY OF YORK
    Inventors: Lorenzo Caputi, Eng-Kiat Lim, Dianna Joy Bowles
  • GLYCOSYLTRANSFERASE ACTIVITY
    Publication number: 20100112615
    Abstract: We describe the production of nucleotide sugars other than uridine diphosphate glucose (UDP-glucose), for example UDP-rhamnose, and the use of these nucleotide sugars in the modification of acceptor molecules.
    Type: Application
    Filed: June 8, 2006
    Publication date: May 6, 2010
    Applicant: THE UNIVERSITY OF YORK
    Inventors: Eng Kiat Lim, Dianna Bowles
  • Bioreactor containing cells expressing glycosyltransferase nucleic acids isolatable from
    Patent number: 7662583
    Abstract: We describe glycosyltransferase nucleic acids and proteins isolatable from Arabidopsis thaliana, transgenic cells expressing said glycosyltransferases, and bioreactors comprising said transgenic cells together with nutrient medium for supporting the growth of said cell that includes at least one exogenous substrate which is a substrate for said glycosyltransferase, and wherein said nutrient medium does not include an exogenous supply of UDP-glucose.
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: February 16, 2010
    Assignee: The University of York
    Inventors: Eng-Kiat Lim, Dianna Bowles
  • Modified Molecule
    Publication number: 20090311731
    Abstract: We describe a microbial cell, typically a bacterial cell, genetically engineered to produce a modified sugar nucleotide, for example UDP glucuronic acid, and the use of the modified sugar to transfer glucuronic acid to small acceptor molecules.
    Type: Application
    Filed: May 25, 2007
    Publication date: December 17, 2009
    Applicant: The University of York
    Inventor: Eng Kiat Lim
  • REGIOSELECTIVE GLYCOSYLATION
    Publication number: 20090280543
    Abstract: We describe a screening method for the identification of glycosyltransferase polypeptides that regioselectively modify aglycones and the use of said glycosyltransferase polypeptides to modify aglycones.
    Type: Application
    Filed: September 21, 2006
    Publication date: November 12, 2009
    Applicant: THE UNIVERSITY OF YORK
    Inventors: Eng-Kiat Lim, Markus Wies
  • Transgenic Cells Expressing Glucosyltransferase Nucleic Acids
    Publication number: 20080209597
    Abstract: The invention relates to transgenic cells which have been transformed with nucleic acids encoding glycosyltransferase polypeptides (GTases) and vectors for use in transformation of said cells.
    Type: Application
    Filed: December 28, 2007
    Publication date: August 28, 2008
    Applicant: The University Of York
    Inventors: Diana Joy Bowles, Yi Li, Eng-Kiat Lim
  • Transgenic cells expressing glucosyltransferase nucleic acids
    Patent number: 7335814
    Abstract: The invention relates to transgenic cells which have been transformed with nucleic acids encoding glucosyltransferase polypeptides (GTases) and vectors for use in transformation of said cells.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: February 26, 2008
    Assignee: The University of York
    Inventors: Diana Joy Bowles, Yi Li, Eng-Kiat Lim
  • Glucosyltransferases which glucosylate abscisic acid
    Publication number: 20040241850
    Abstract: The invention relates to transgenic cells which have been transformed with glucosyltransferase nucleic acids which encode glucosyltransferases which glucosylate abscisic acid, or analogues thereof; the use of said glucosyltransferases in screens for agents with herbicidal activity and in the production and/or testing of abscisic acid, or analogues thereof.
    Type: Application
    Filed: March 11, 2004
    Publication date: December 2, 2004
    Inventors: Rosamond Jackson, Yi Li, Eng-Kiat Lim, Dianna Joy Bowles
  • Transgenic cells expressing glucosyltransferase nucleic acids
    Publication number: 20030226162
    Abstract: The invention relates to transgenic cells which have been transformed with nucleic acids encoding glucosyltransferase polypeptides (GTases) and vectors for use in transformation of said cells.
    Type: Application
    Filed: December 3, 2002
    Publication date: December 4, 2003
    Inventors: Diana Joy Bowles, Yi Li, Eng-Kiat Lim