Patents by Inventor Enming Joe Su

Enming Joe Su has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of reducing the effect of a stroke comprising administering an inhibitor of vascular endothelial growth factor B (VEGF-B)
    Patent number: 10961304
    Abstract: A method of reducing an effect of stroke in a subject, the method comprising administering to the subject a compound that inhibits VEGF-B signaling.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: March 30, 2021
    Assignees: CSL Limited, B-Creative Sweden AB
    Inventors: Ulf Eriksson, Ingrid Nilsson, Daniel Lawrence, Enming Joe Su
  • METHOD OF TREATING OR PREVENTING STROKE
    Publication number: 20190315849
    Abstract: A method of reducing an effect of stroke in a subject, the method comprising administering to the subject a compound that inhibits VEGF-B signaling.
    Type: Application
    Filed: May 14, 2019
    Publication date: October 17, 2019
    Applicants: CSL Limited, B-Creative Sweden AB
    Inventors: Ulf ERIKSSON, Ingrid NILSSON, Daniel LAWRENCE, Enming Joe SU
  • Method of treating stroke by administering a compound that inhibits VEGF-B signaling in combination with a thrombolytic agent
    Patent number: 10336821
    Abstract: A method of reducing an effect of stroke in a subject, the method comprising administering to the subject a compound that inhibits VEGF-B signaling.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: July 2, 2019
    Assignees: CSL Limited, B-Creative Sweden AB
    Inventors: Ulf Eriksson, Ingrid Nilsson, Daniel Lawrence, Enming Joe Su
  • METHOD OF TREATING OR PREVENTING STROKE
    Publication number: 20180237513
    Abstract: A method of reducing an effect of stroke in a subject, the method comprising administering to the subject a compound that inhibits VEGF-B signaling
    Type: Application
    Filed: November 17, 2015
    Publication date: August 23, 2018
    Applicants: CSL Limited, B-Creative Sweden AB
    Inventors: Ulf ERIKSSON, Ingrid NILSSON, Daniel LAWRENCE, Enming Joe SU
  • Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
    Patent number: 9527878
    Abstract: The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: December 27, 2016
    Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, EASTERN MICHIGAN UNIVERSITY
    Inventors: Daniel A. Lawrence, Cory Emal, Jacqueline Cale, Enming Joe Su, Mark Warnock, Shih-Hon Li, Jeanne Ann Cupp
  • PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF TO MODULATE LIPID METABOLISM
    Publication number: 20160009748
    Abstract: The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
    Type: Application
    Filed: August 4, 2015
    Publication date: January 14, 2016
    Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, EASTERN MICHIGAN UNIVERSITY
    Inventors: Daniel A. Lawrence, Cory Emal, Jacqueline Cale, Enming Joe Su, Mark Warnock, Shih-Hon Li, Jeanne Ann Cupp
  • Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
    Patent number: 9096501
    Abstract: The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: August 4, 2015
    Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, UNIVERSITY OF MARYLAND, BALTIMORE, EASTERN MICHIGAN UNIVERSITY
    Inventors: Daniel A. Lawrence, Dudley Strickland, Jacqueline Cale, Enming Joe Su, Cory Emal, Mark Warnock
  • Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism
    Publication number: 20140343321
    Abstract: The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
    Type: Application
    Filed: May 21, 2014
    Publication date: November 20, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Daniel A. Lawrence, Dudley Strickland, Jacqueline Cale, Enming Joe Su, Cory Emal, Mark Warnock
  • Methods and compositions for modulation of blood-neural barrier
    Patent number: 8765671
    Abstract: Methods and compositions for modulating blood-neural barrier (BNB) for the treatment of CNS conditions such as edema, and for increased drug delivery efficacy across the BNB. The present invention further relates to improved tPA treatment of ischemic cerebrovascular and related diseases in combination with antagonism of the PDGF signaling pathway. The inventive method and composition is particularly suitable for conjunctive therapy of ischemic stroke using tPA and an anti-PDGF-C antagonist or an anti-PDGFR-? antagonist.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: July 1, 2014
    Assignees: Ludwig Institute for Cancer Research, University of Maryland, The Regents of the University of Michigan
    Inventors: Ulf Eriksson, Daniel Lawrence, Enming Joe Su, Dudley Strickland, Manuel Yepes, Linda Fredriksson
  • METHODS AND COMPOSITIONS FOR MODULATION OF BLOOD-NEURAL BARRIER
    Publication number: 20120156187
    Abstract: Methods and compositions for modulating blood-neural barrier (BNB) for the treatment of CNS conditions such as edema, and for increased drug delivery efficacy across the BNB. The present invention further relates to improved tPA treatment of ischemic cerebrovascular and related diseases in combination with antagonism of the PDGF signaling pathway. The inventive method and composition is particularly suitable for conjunctive therapy of ischemic stroke using tPA and an anti-PDGF-C antagonist or an anti-PDGFR-? antagonist.
    Type: Application
    Filed: February 28, 2012
    Publication date: June 21, 2012
    Applicants: LUDWIG INSTITUTE FOR CANCER RESEARCH, THE REGENTS OF THE UNIVERSITY OF MICHIGAN, UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Ulf Eriksson, Daniel Lawrence, Enming Joe Su, Dudley Strickland, Manuel Yepes, Linda Fredriksson
  • Methods and compositions for modulation of blood-neural barrier
    Patent number: 8147828
    Abstract: Methods and compositions for modulating blood-neural barrier (BNB) for the treatment of CNS conditions such as edema, and for increased drug delivery efficacy across the BNB. The present invention further relates to improved tPA treatment of ischemic cerebrovascular and related diseases in combination with antagonism of the PDGF signaling pathway. The inventive method and composition is particularly suitable for conjunctive therapy of ischemic stroke using tPA and an anti-PDGF-C antagonist or an anti-PDGFR-? antagonist.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: April 3, 2012
    Assignees: Ludwig Institute for Cancer Research, University of Maryland, The Regents of the University of Michigan
    Inventors: Ulf Eriksson, Daniel Lawrence, Enming Joe Su, Dudley Strickland, Manuel Yepes, Linda Fredriksson