Patents by Inventor Enming Xing

Enming Xing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BET PROTEIN INHIBITORS AND USE THEREOF
    Publication number: 20240189304
    Abstract: Methods for the treatment of condition associated with bromodomain and extraterminal domain (BET) protein activity are disclosed. The methods include administering a therapeutically effective amount of a piperazine BET protein inhibitor or a piperidine BET protein inhibitor to a subject in need thereof. Piperazine BET protein inhibitors, piperidine BET protein inhibitors, and pharmaceutical compositions comprising the BET proteins inhibitors are also described.
    Type: Application
    Filed: March 2, 2022
    Publication date: June 13, 2024
    Applicants: The Regents of the University of California, Ohio State Innovation Foundation, The United States Government as represented by the Department of Veterans Affairs
    Inventors: Allen C. Gao, Pui-Kai Li, Mark Foster, Ross Larue, Cameron M. Armstrong, Wei Lou, Shu Ning, Enming Xing
  • DUAL ANDROGEN RECEPTOR/AKR1C3 INHIBITORS
    Publication number: 20230022235
    Abstract: The present invention provides benzamide compounds, compositions containing the benzamides, and use of the benzamides for inhibiting androgen receptor (AR) and/or aldo-keto reductase family 1 member C3 (AKR1C3). Also described herein methods for the treatment of hormone-mediated diseases and conditions, including hormone-related cancers such as castration resistant prostate cancer.
    Type: Application
    Filed: May 16, 2022
    Publication date: January 26, 2023
    Applicants: The Regents of the University of California, Ohio State Innovation Foundation, The United States Government as represented by the Department of Veterans Affairs
    Inventors: Allen C. Gao, Pui-Kai Li, Enming Xing, Xiaolin Cheng, Xiaotian Kong, Wei Lou