Patents by Inventor Enqing Tan
Enqing Tan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230408517Abstract: Anti-SARS-CoV-specific monoclonal antibodies, methods of making and characterizing those antibodies, and methods of using those antibodies are described herein. In some embodiments, the antibodies may bind to both SARS-CoV-1 and SARS-CoV-2. In some embodiments, the antibodies bind to S1 of the spike protein of SARS-CoV-2 including, for example, to the receptor binding domain (RBD) of S1. In some embodiments, the antibodies may block the binding of SARS-CoV-1 and/or SARS-CoV-2 to ACE-2. Such antibodies are useful as diagnostic and therapeutic agents.Type: ApplicationFiled: November 24, 2021Publication date: December 21, 2023Inventors: Christine Andrea Goetz, Jody Bonnevier, Christopher David Hammerbeck, Ernesto Rubin Resnik, Cyrus B. Munshi, Enqing Tan
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Patent number: 10953398Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: GrantFiled: December 1, 2017Date of Patent: March 23, 2021Assignee: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Patent number: 10413899Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions.Type: GrantFiled: July 12, 2017Date of Patent: September 17, 2019Assignee: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder
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Publication number: 20180078938Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: ApplicationFiled: December 1, 2017Publication date: March 22, 2018Applicant: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Patent number: 9861980Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: GrantFiled: December 20, 2016Date of Patent: January 9, 2018Assignee: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Publication number: 20170304822Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions.Type: ApplicationFiled: July 12, 2017Publication date: October 26, 2017Applicant: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder
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Patent number: 9731291Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions.Type: GrantFiled: May 19, 2015Date of Patent: August 15, 2017Assignee: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder
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Publication number: 20170165664Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: ApplicationFiled: December 20, 2016Publication date: June 15, 2017Applicant: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Patent number: 9555408Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: GrantFiled: October 23, 2014Date of Patent: January 31, 2017Assignee: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Publication number: 20150251178Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions.Type: ApplicationFiled: May 19, 2015Publication date: September 10, 2015Applicant: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder
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Patent number: 9075051Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: GrantFiled: April 22, 2013Date of Patent: July 7, 2015Assignee: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder
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Publication number: 20150044760Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: ApplicationFiled: October 23, 2014Publication date: February 12, 2015Applicant: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Patent number: 8915259Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: GrantFiled: September 27, 2013Date of Patent: December 23, 2014Assignee: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Publication number: 20140093866Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: ApplicationFiled: September 27, 2013Publication date: April 3, 2014Applicant: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Patent number: 8615367Abstract: Disclosed is number coding of pairs (“doublets”) or small sets (“multiplets”) of solid phase carriers which provides distinguishable subtypes of a given type of such carriers, where each carrier type is distinguishable on the bases of a different code. Such number coding is useful for augmenting a coding system, such as a color code, and thereby effectively multiplying the number of “colors” (distinguishable sub-types). It can be applied, for example, to determine whether a sample is homozygous or heterozygous at a number of different sites for one of two different alleles, where the same color code is applied for each of the two alleles, and the alleles with the same color code are distinguished by knowing how many carriers are associated with molecules which detect each different allele.Type: GrantFiled: March 24, 2011Date of Patent: December 24, 2013Assignee: Bioarray Solutions, Ltd.Inventors: Michael Seul, Chiu Wo Chau, Enqing Tan
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Patent number: 8567425Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: GrantFiled: November 24, 2010Date of Patent: October 29, 2013Assignee: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Publication number: 20130236375Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: ApplicationFiled: April 22, 2013Publication date: September 12, 2013Applicant: OPKO Diagnostics, LLCInventors: Enqing Tan, Vincent Linder
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Publication number: 20110184655Abstract: Disclosed is number coding of pairs (“doublets”) or small sets (“multiplets”) of solid phase carriers which provides distinguishable subtypes of a given type of such carriers, where each carrier type is distinguishable on the bases of a different code. Such number coding is useful for augmenting a coding system, such as a color code, and thereby effectively multiplying the number of “colors” (distinguishable sub-types). It can be applied, for example, to determine whether a sample is homozygous or heterozygous at a number of different sites for one of two different alleles, where the same color code is applied for each of the two alleles, and the alleles with the same color code are distinguished by knowing how many carriers are associated with molecules which detect each different allele.Type: ApplicationFiled: March 24, 2011Publication date: July 28, 2011Applicant: BioArray Solutions, Ltd.Inventors: Michael Seul, Enqing Tan, Chiu Chau
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Publication number: 20110120562Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.Type: ApplicationFiled: November 24, 2010Publication date: May 26, 2011Applicant: Claros Diagnostics, Inc.Inventors: Enqing Tan, Vincent Linder, Jason Taylor, David Steinmiller
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Patent number: 7927796Abstract: Disclosed is number coding of pairs (“doublets”) or small sets (“multiplets”) of solid phase carriers which provides distinguishable subtypes of a given type of such carriers, where each carrier type is distinguishable on the basis of a different code. Such number coding is useful for augmenting a coding system, such as a color code, and thereby effectively multiplying the number of “colors” (distinguishable sub-types). It can be applied, for example, to determine whether a sample is homozygous or heterozygous at a number of different sites for one of two different alleles, where the same color code is applied for each of the two alleles, and the alleles with the same color code are distinguished by knowing how many carriers are associated with molecules which detect each different allele.Type: GrantFiled: September 17, 2004Date of Patent: April 19, 2011Assignee: BioArray Solutions, Ltd.Inventors: Michael Seul, Enqing Tan, Chiu Chau