Patents by Inventor Enrico Millo

Enrico Millo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic application of (Boc)-creatine
    Patent number: 9700539
    Abstract: A creatine derivative, (Boc)2-creatine, is used as a medicament, in particular in a therapeutic antitumor treatment. I (Boc)2-creatine.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: July 11, 2017
    Assignee: UNIVERSITA' DEGLI STUDI DI GENOVA
    Inventors: Patrizia Garbati, Maurizio Balestrino, Enrico Adriano, Silvia Ravera, Enrico Millo, Gianluca Damonte, Annalisa Salis
  • THERAPEUTIC APPLICATION OF (BOC)2-CREATINE
    Publication number: 20170000757
    Abstract: A creatine derivative, (Boc)2-creatine, is used as a medicament, in particular in a therapeutic antitumor treatment. I (Boc)2-creatine.
    Type: Application
    Filed: December 23, 2014
    Publication date: January 5, 2017
    Inventors: Patrizia GARBATI, Maurizio BALESTRINO, Enrico ADRIANO, Silvia RAVERA, Enrico MILLO, Gianluca DAMONTE, Annalisa SALIS
  • A METHOD OF SYNTHESIZING CREATINE DERIVATIVES
    Publication number: 20150368192
    Abstract: A method of synthesizing (Boc)2-creatine derivatives of formula (III) which comprises a first step in which a sarcosine ester is reacted with a guanylating agent comprising two nitrogen atoms each protected with a t-butoxycarbonyl (t-Boc) group to form a (Boc)2-creatine ester, and a second step in which the (Boc)2-creatine ester is subjected basic hydrolysis to form (Boc)2-creatine of formula (III) is described. The (Boc)2-creatine so obtained can be used in methods of synthesizing creatine and phosphocreatine derivatives in which the free carboxyl group of the creatine is conjugated with a desired molecule.
    Type: Application
    Filed: November 18, 2013
    Publication date: December 24, 2015
    Inventors: Enrico Millo, Maurizio Balestrino, Gianluca Damonte, Patrizia Garbati, Enrico Adriano, Annalisa Salis
  • Planar support having an ultraflat surface and a device for detecting antigens comprising said planar support
    Patent number: 8932991
    Abstract: A nanoarray or microarray of antibodies includes a planar surface having an ultraflat surface, which has a planar substrate functionalized with a first monolayer of linking molecules, preferably APTES molecules, and a second monolayer of small peptides of the general formula (I) capable of binding the Fc region of antibodies. The nanoarray or microarray includes capture antibodies immobilized on the planar support, preferably in the form of a matrix of spots, and is suitable to be used for detecting antigens in a biological sample by AFM imaging. Z—HN—R1—R2—R3—R4—R5—R6—NH—X—CO-G-COOH.
    Type: Grant
    Filed: July 4, 2011
    Date of Patent: January 13, 2015
    Assignee: Universita' Degli Studi de Genova
    Inventors: Francesca Ferrera, Vincenzo Ierardi, Gilberto Filaci, Enrico Millo, Gianluca Damonte, Francesco Indiveri, Ugo Valbusa
  • PLANAR SUPPORT HAVING AN ULTRAFLAT SURFACE AND A DEVICE FOR DETECTING ANTIGENS COMPRISING SAID PLANAR SUPPORT
    Publication number: 20130109591
    Abstract: A nanoarray or microarray of antibodies includes a planar surface having an ultraflat surface, which has a planar substrate functionalized with a first monolayer of linking molecules, preferably APTES molecules, and a second monolayer of small peptides of the general formula (I) capable of binding the Fc region of antibodies. The nanoarray or microarray includes capture antibodies immobilized on the planar support, preferably in the form of a matrix of spots, and is suitable to be used for detecting antigens in a biological sample by AFM imaging.
    Type: Application
    Filed: July 4, 2011
    Publication date: May 2, 2013
    Applicant: UNIVERSITA' DEGLI STUDI DI GENOVA
    Inventors: Francesca Ferrera, Vincenzo Ierardi, Gilberto Filaci, Enrico Millo, Gianluca Damonte, Francesco Indiveri, Ugo Valbusa
  • Glutathione Derivatives and Their Uses for the Treatment of Viral Diseases
    Publication number: 20120165248
    Abstract: Glutathione derivatives (GSH) of formula I are provided, wherein R is a thiol protection group. The derivatives are useful for the treatment of infections from Paramyxovirus, Orthomyxovirus, Herpes Simplex Virus and Acquired Immunodeficiency Syndrome Virus.
    Type: Application
    Filed: October 12, 2011
    Publication date: June 28, 2012
    Applicant: fiRST S.r.l.
    Inventors: Umberto Benatti, Giorgio Brandi, Enrico Garaci, Mauro Magnani, Enrico Millo, Anna Taresa Palamara, Luigia Rossi
  • Glutathione Derivatives and Their Uses for the Treatment of Viral Diseases
    Publication number: 20070270349
    Abstract: Glutathione derivatives (GSH) of formula (I) are provided, wherein R is a thiol protection group. The derivatives are useful for the treatment of infections from Paramyxovirus, Orthomyxovirus, Herpes Simplex Virus and Acquired Immunodeficiency Syndrome Virus.
    Type: Application
    Filed: December 29, 2004
    Publication date: November 22, 2007
    Inventors: Umberto Benatti, Giorgio Brandi, Enrico Garaci, Mauro Magnani, Enrico Millo, Anna Palamara, Luigia Rossi