Patents by Inventor Enrico Modena

Enrico Modena has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline Forms of 4-amino-N-[4-(methoxymethyl)phenyl]-7-(1-methylcyclopropyl)-6-(3-morpholinoprop-1-yn-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide
    Publication number: 20240010653
    Abstract: Provided herein are various crystalline forms of 4-amino-N-[4-(methoxymethyl)phenyl]-7-(1-methylcyclopropyl)-6-(3-morpholinoprop-1-yn-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide, methods of producing same, and methods of using same to for RET inhibition.
    Type: Application
    Filed: November 18, 2021
    Publication date: January 11, 2024
    Applicant: Helsinn Healthcare SA
    Inventors: Gionata Frasca, Tiziano Fumagalli, Stefano Luca Giaffreda, Enrico Modena, Cristina Ianni
  • Tianeptine oxalate salts and polymorphs
    Patent number: 10946027
    Abstract: Disclosed herein is an oxalate salt/co-crystal (tianeptine oxalate) of (RS)-7-(3-chloro-6-methyl-6,11-dihydrodibenzo[c,f] [1,2]thiazepin-11-ylamino)heptanoic acid S,S-dioxide (tianeptine) as shown in Formula I:
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: March 16, 2021
    Assignee: Tonix Pharma Holdings Limited
    Inventors: Stefano Luca Giaffreda, Enrico Modena, Serena Fabbroni, Michel Chiarucci, Mark T. Edgar
  • Crystal forms of lenvatinib
    Patent number: 10836727
    Abstract: The present invention provides novel crystalline forms of 4-[3-Chloro-4-(N?-cyclopropylureido)phenoxy]-7-methoxyquinoline-6-carboxamide methanesulfonate, as well as methods for their preparation.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: November 17, 2020
    Assignee: Indena S.P.A.
    Inventors: Nicola Sardone, Stefano Luca Giaffreda, Andrea Gambini, Alex Petrolati, Pietro Allegrini, Enrico Modena
  • TIANEPTINE OXALATE SALTS AND POLYMORPHS
    Publication number: 20200276208
    Abstract: Disclosed herein is an oxalate salt/co-crystal (tianeptine oxalate) of (RS)-7-(3-chloro-6-methyl-6,11-dihydrodibenzo[c,f] [1,2]thiazepin-11-ylamino)heptanoic acid S,S-dioxide (tianeptine) as shown in Formula I:
    Type: Application
    Filed: October 9, 2019
    Publication date: September 3, 2020
    Inventors: Stefano Luca Giaffreda, Enrico Modena, Serena Fabbroni, Michel Chiarucci, Mark T. Edgar
  • Tianeptine oxalate salts and polymorphs
    Patent number: 10449203
    Abstract: Disclosed herein is an oxalate salt/co-crystal (tianeptine oxalate) of (RS)-7-(3-chloro-6-methyl-6,11-dihydrodibenzo[c,f] [1,2]thiazepin-11-ylamino)heptanoic acid S,S-dioxide (tianeptine) as shown in Formula I:
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: October 22, 2019
    Assignee: Tonix Pharma Holdings Limited
    Inventors: Stefano Luca Giaffreda, Enrico Modena, Serena Fabbroni, Michel Chiarucci, Mark T. Edgar
  • NEW CRYSTAL FORMS OF LENVATINIB
    Publication number: 20190256473
    Abstract: The present invention provides novel crystalline forms of 4-[3-Chloro-4-(N?-cyclopropylureido)phenoxy]-7-methoxyquinoline-6-carboxamide methanesulfonate, as well as methods for their preparation.
    Type: Application
    Filed: September 15, 2017
    Publication date: August 22, 2019
    Applicant: Indena S.P.A.
    Inventors: Nicola Sardone, Stefano Luca Giaffreda, Andrea Gambini, Alex Petrolati, Pietro Allegrini, Enrico Modena
  • TIANEPTINE OXALATE SALTS AND POLYMORPHS
    Publication number: 20180338984
    Abstract: Disclosed herein is an oxalate salt/co-crystal (tianeptine oxalate) of (RS)-7-(3-chloro-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-ylamino)heptanoic acid S,S-dioxide (tianeptine) as shown in Formula I:
    Type: Application
    Filed: December 28, 2017
    Publication date: November 29, 2018
    Inventors: Stefano Luca Giaffreda, Enrico Modena, Serena Fabbroni, Michel Chiarucci, Mark T. Edgar