Patents by Inventor Enrico Perfler

Enrico Perfler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230088141
    Abstract: The present invention relates to a device for delivering acetylsalicylic acid or a salt thereof for the administration thereof through oral inhalation route for the preventive or curative treatment of thrombohemolytic events, in particular for myocardial infarction.
    Type: Application
    Filed: March 17, 2021
    Publication date: March 23, 2023
    Inventor: Enrico PERFLER
  • Publication number: 20220098549
    Abstract: A method for characterising a tissue-engineered construct and the tissue-engineered construct are described. The characterisation method allows verification of viability, morphology, functionality and/or distribution of cells comprised in the tissue-engineered construct. The tissue-engineered construct has a scaffold with a lumen and at least one portion of the lumen lined with at least one functional and preferably continuous cell layer, that can be used for in vitro testing of medicinal products for human or animal use. A method for the in vitro testing of medicinal products for human or animal use performed with the tissue-engineered construct is also described.
    Type: Application
    Filed: February 14, 2020
    Publication date: March 31, 2022
    Inventors: Enrico PERFLER, Andrea BIFFI, Stefano FARINA
  • Publication number: 20210222130
    Abstract: The present invention refers to a model for in-vitro simulation of the behaviour of dysfunctional human vessels, such as for example vessels affected by aneurysm, stenosis or sclerosis plaques, as an instrument for testing medical devices and drugs with the aim of verifying effectiveness and safety thereof prior to use thereof on humans. Specifically, the present invention refers to an in vitro model of a substantially tubular-shaped vascular structure having dysfunctional anatomical and physiological characteristics simulating the same vascular structure of a healthy subject whose vascular structure has been damaged or deformed or deteriorated due to a damage selected from among the group comprising or, alternatively, consisting of aneurysm, stenosis, sclerosis plaques, forms of tumours or cardiomyopathies having the characteristics as claimed in the attached claims.
    Type: Application
    Filed: August 5, 2019
    Publication date: July 22, 2021
    Inventors: Enrico PERFLER, Andrea BIFFI, Stefano FARINA
  • Publication number: 20210212760
    Abstract: The present invention relates to an ablation catheter (1) for the ablation of tissues comprising: a telescopic tubular body (4) in turn comprising an external tubular body (4a) and an internal tubular body (4b) concentric with each other, and a rod-like guiding element (5) at least partly housed in the internal tubular body (4b) with at least one free end (5a) protruding from the internal tubular body (4b) in correspondence with a distal end of the telescopic body (4); a positioning head (2, 2?, 2??, 2°, 2*, 2{circumflex over (?)}) and an ablation head (3) in correspondence with the distal end of the telescopic body (4), the positioning head (2,2?,2??,2?,2*,2{circumflex over (?)}) being situated in the proximity of the free end (5a) of the rod-like guide, and the ablation head (3) in the proximity of the positioning head (2, 2?, 2??, 2°, 2*, 2{circumflex over (?)}), in a remote position with respect to the free end (5a); a control handpiece at a proximal end of the telescopic body (4) coupled with the guiding
    Type: Application
    Filed: March 29, 2021
    Publication date: July 15, 2021
    Inventor: Enrico PERFLER
  • Patent number: 10980597
    Abstract: An ablation catheter equipped with ablation petals having electrodes that are continuous over an outer circumferential portion of the ablation petals. The ablation catheter can be moved from a rest position, where the petals are housed in an external tubular body, to an operating position, where the petals protrude from the external tubular body.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: April 20, 2021
    Assignee: ElectroPhysiology Frontiers S.p.A.
    Inventor: Enrico Perfler
  • Publication number: 20170151014
    Abstract: The present invention relates to an ablation catheter (1) for the ablation of tissues comprising: a telescopic tubular body (4) in turn comprising an external tubular body (4a) and an internal tubular body (4b) concentric with each other, and a rod-like guiding element (5) at least partly housed in the internal tubular body (4b) with at least one free end (5a) protruding from the internal tubular body (4b) in correspondence with a distal end of the telescopic body (4); a positioning head (2, 2?, 2??, 2°, 2*, 2?) and an ablation head (3) in correspondence with the distal end of the telescopic body (4), the positioning head (2,2?,2??,2?,2*,2?) being situated in the proximity of the free end (5a) of the rod-like guide, and the ablation head (3) in the proximity of the positioning head (2, 2?, 2??, 2°, 2*, 2?), in a remote position with respect to the free end (5a); a control handpiece at a proximal end of the telescopic body (4) coupled with the guiding element (5), the ablation head (3), the positioning head (2
    Type: Application
    Filed: March 18, 2015
    Publication date: June 1, 2017
    Inventor: Enrico Perfler
  • Patent number: 9259235
    Abstract: A device for electrically isolating pulmonary veins in atrial fibrillation for treatment thereof by ablation of a circumferential zone of tissue. The device includes a catheter (with terminal and distal parts) and comprising a first tubular element; a second tubular element concentric with the first tubular element and an axial rod-like element which extends beyond the distal end of the first and second tubular elements; and a first tubular toroidal element supported by tubular arms extending from the distal end towards the toroidal element, forming a cage which can be opened in umbrella fashion around the distal end of the catheter. The tubular arms and the toroidal element are in fluid communication with each other and with the tubular element of the catheter. The device also includes a second toroidal tubular element in fluid communication by means of the radial arms with the first tubular element of the catheter.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: February 16, 2016
    Assignee: ATRICATH S.R.L.
    Inventors: Gian Battista Chierchia, Enrico Perfler
  • Publication number: 20140052062
    Abstract: Device for electrically isolating the pulmonary veins in atrial fibrillation for treatment thereof by means of ablation of a circumferential zone of tissue in a position where a pulmonary vein extends from an atrium, comprising: a catheter (1) having a terminal part and a distal part and comprising a first tubular element (2); a second tubular element (4) concentric with said first tubular element (2) and an axial rod-like element (6) which extends beyond the distal end of said first and second tubular elements (2; 4); a first tubular toroidal element (13) supported by a plurality of tubular arms (11) which extend from said distal end towards said toroidal element (13) forming a kind of cage which can be opened in umbrella fashion around the distal end of said catheter (1), said tubular arms (11) and said toroidal element (13) being in fluid communication with each other and with said second tubular element (4) of said catheter (1); and a second toroidal tubular element (9) in fluid communication by means of
    Type: Application
    Filed: April 12, 2012
    Publication date: February 20, 2014
    Inventors: Gian Battista Chierchia, Enrico Perfler