Patents by Inventor Enrico Velardi

Enrico Velardi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LUTEINIZING HORMONE RECEPTOR BINDING AGENTS AND LUTEINIZING HORMONE AGONISTS TO IDENTIFY, EXPAND, ABLATE AND MODIFY STEM CELLS
    Publication number: 20240091265
    Abstract: The use of luteinizing hormone receptor (LHR) binding agents and luteinizing hormone (LH) agonists to enrich for primitive hematopoietic stem cell (pHSC) populations, to target pHSC for ablation, and/or to expand pHSC populations are described. The methods can be used to prepare therapeutic hematopoietic stem cell (HSC) populations, to prepare patients for therapeutic HSC transplants, and/or to treat malignancies, such as those associated with hyperproliferative HSC.
    Type: Application
    Filed: June 12, 2023
    Publication date: March 21, 2024
    Applicants: Fred Hutchinson Cancer Center, Memorial Sloan-Kettering Cancer Center
    Inventors: Jarrod Dudakov, Marcel van den Brink, Enrico Velardi, Hans-Peter Kiem, Stefan Radtke, Scott James
  • Luteinizing hormone receptor binding agents and luteinizing hormone agonists to identify, expand, ablate and modify stem cells
    Patent number: 11786557
    Abstract: The use of luteinizing hormone receptor (LHR) binding agents and luteinizing hormone (LH) agonists to enrich for primitive hematopoietic stem cell (pHSC) populations, to target pHSC for ablation, and/or to expand pHSC populations are described. The methods can be used to prepare therapeutic hematopoietic stem cell (HSC) populations, to prepare patients for therapeutic HSC transplants, and/or to treat malignancies, such as those associated with hyperproliferative HSC.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: October 17, 2023
    Assignee: Fred Hutchinson Cancer Center
    Inventors: Jarrod Dudakov, Marcel van den Brink, Enrico Velardi, Hans-Peter Kiem, Stefan Radtke, Scott James
  • HEMATOPOIETIC RECOVERY FROM RADIATION INJURY
    Publication number: 20200268852
    Abstract: Described herein are methods for the treatment of radiation injury by administration of sex steroid inhibitory (SSI) agents.
    Type: Application
    Filed: March 4, 2020
    Publication date: August 27, 2020
    Applicant: Memorial Sloan Kettering Cancer Center
    Inventors: Jarrod A. Dudakov, Marcel R.M. van den Brink, Enrico Velardi
  • LUTEINIZING HORMONE RECEPTOR BINDING AGENTS AND LUTEINIZING HORMONE AGONISTS TO IDENTIFY, EXPAND, ABLATE AND MODIFY STEM CELLS
    Publication number: 20200237827
    Abstract: The use of luteinizing hormone receptor (LHR) binding agents and luteinizing hormone (LH) agonists to enrich for primitive hematopoietic stem cell (pHSC) populations, to target pHSC for ablation, and/or to expand pHSC populations are described. The methods can be used to prepare therapeutic hematopoietic stem cell (HSC) populations, to prepare patients for therapeutic HSC transplants, and/or to treat malignancies, such as those associated with hyperproliferative HSC.
    Type: Application
    Filed: October 2, 2018
    Publication date: July 30, 2020
    Applicants: Fred Hutchinson Cancer Research Center, Memorial Sloan Kettering Cancer Center
    Inventors: Jarrod Dudakov, Marcel van den Brink, Enrico Velardi, Hans-Peter Kiem, Stefan Radtke, Scott James
  • HEMATOPOIETIC RECOVERY FROM RADIATION INJURY
    Publication number: 20160263196
    Abstract: Described herein are methods for the treatment of radiation injury by administration of sex steroid inhibitory (SSI) agents.
    Type: Application
    Filed: November 3, 2014
    Publication date: September 15, 2016
    Inventors: Jarrod A. Dudakov, Marcel R.M. van den Brink, Enrico Velardi