Patents by Inventor Enrique Abola

Enrique Abola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Determining structures by performing comparisons between molecular replacement results for multiple different biomolecules
    Patent number: 7158888
    Abstract: A method is provided for identifying a search model to use in molecular replacement for determining a structure of a target biomolecule, such as a protein, from X-ray diffraction data, the method comprising: employing computer executable logic to perform multiple molecular replacement searches on X-ray diffraction data of the target biomolecule where a group of different biomolecule structures are used as search models for the multiple molecular replacement searches; and employing computer executable logic to compare solutions from the multiple molecular replacement searches, the comparison producing data from which biomolecule structures can be identified as having superior structural identity with the target biomolecule as compared to the other biomolecule structures in the group.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: January 2, 2007
    Assignee: Takeda San Diego, Inc.
    Inventors: Duncan McRee, Peter R. David, Frank von Delft, John Rammelkamp, Enrique Abola
  • Determining structures by performing comparisons between molecular replacement results for multiple different biomolecules
    Publication number: 20020183861
    Abstract: A method is provided for identifying a search model to use in molecular replacement for determining a structure of a target biomolecule, such as a protein, from X-ray diffraction data, the method comprising: employing computer executable logic to perform multiple molecular replacement searches on X-ray diffraction data of the target biomolecule where a group of different biomolecule structures are used as search models for the multiple molecular replacement searches; and employing computer executable logic to compare solutions from the multiple molecular replacement searches, the comparison producing data from which biomolecule structures can be identified as having superior structural identity with the target biomolecule as compared to the other biomolecule structures in the group.
    Type: Application
    Filed: May 4, 2001
    Publication date: December 5, 2002
    Inventors: Duncan McRee, Peter R. David, Frank von Delft, John Rammelkamp, Enrique Abola