Patents by Inventor Enrique Poradosu

Enrique Poradosu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240075006
    Abstract: Described herein are methods fir treating patients with iron-deficiency anemia (IDA), comprising administering ferric citrate to such patients. In certain aspects, the patients treated for iron-deficiency anemia have a gastrointestinal disorder, such as inflammatory bowel disease, inflammatory bowel syndrome, Crohn's disease, microscopic colitis (such as collagenous or lymphocytic colitis), or chemically-induced colitis (e.g., NSAID (nonsteroidal anti-inflammatory drug)-induced colitis). In certain aspects, the patients treated for iron-deficiency anemia have blood loss associated with childbirth, menstruation or infection. In some aspects, the patients treated for iron-deficiency anemia have insufficient dietary intake of iron and/or insufficient absorption of iron.
    Type: Application
    Filed: December 21, 2022
    Publication date: March 7, 2024
    Inventors: Enrique Poradosu, Ron Bentsur, Shay David Shemesh
  • Publication number: 20240041816
    Abstract: Methods of administering ferric citrate to reduce and/or control serum phosphorus levels, increase serum bicarbonate levels, improve one or more iron storage parameters (e.g., increase serum ferritin levels, increase transferrin saturation (TSAT), increase hemoglobin concentration) increase iron absorption, maintain iron stores, treat iron deficiency, treat anemia, reduce the need for IV iron and/or reduce the need for erythropoiesis-stimulating agents (ESAs) in chronic kidney disease patients, are disclosed.
    Type: Application
    Filed: December 28, 2022
    Publication date: February 8, 2024
    Inventors: Enrique Poradosu, James F. Oliviero, III, Ron Bentsur
  • Publication number: 20220202824
    Abstract: Disclosed herein are methods for treating centronuclear myopathies, such as myotubular myopathy, in a subject in need thereof, comprising administering to the subject in need thereof an effective amount of 3-{[(3S)-4-(6,6-dimethyl-4-oxo-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)morpholin-3-yl]methyl}-N,N,1-trimethyl-1H-indole-5-carboxamide and/or a pharmaceutically acceptable form thereof.
    Type: Application
    Filed: September 13, 2019
    Publication date: June 30, 2022
    Applicant: Stemline Therapeutics, Inc.
    Inventors: Enrique Poradosu, Thomas Bartholomew Crabbe
  • Publication number: 20190307791
    Abstract: Methods of administering ferric citrate to reduce and/or control serum phosphorus levels, increase serum bicarbonate levels, improve one or more iron storage parameters (e.g., increase serum ferritin levels, increase transferrin saturation (TSAT), increase hemoglobin concentration), increase iron absorption, maintain iron stores, treat iron deficiency, treat anemia, reduce the need for IV iron, reduce the need for erythropoiesis-stimulating agents (ESAs), and/or reduce mortality and morbidity related to adverse cardiac events in chronic kidney disease patients, are disclosed.
    Type: Application
    Filed: December 11, 2018
    Publication date: October 10, 2019
    Applicant: KERYX BIOPHARMACEUTICALS, INC.
    Inventors: Enrique PORADOSU, Ron BENTSUR, James F. OLIVIERO
  • Publication number: 20190269645
    Abstract: Methods of administering ferric citrate to reduce and/or control serum phosphorus levels, increase serum bicarbonate levels, improve one or more iron storage parameters (e.g., increase serum ferritin levels, increase transferrin saturation (TSAT), increase hemoglobin concentration) increase iron absorption, maintain iron stores, treat iron deficiency, treat anemia, reduce the need for IV iron and/or reduce the need for erythropoiesis-stimulating agents (ESAs) in chronic kidney disease patients, are disclosed.
    Type: Application
    Filed: October 8, 2018
    Publication date: September 5, 2019
    Applicant: Keryx Biopharmaceuticals, Inc.
    Inventors: Enrique Poradosu, James F. Oliviero, III, Ron Bentsur
  • Publication number: 20180071243
    Abstract: Described herein are methods for treating patients with iron-deficiency anemia (IDA), comprising administering ferric citrate to such patients. In certain aspects, the patients treated for iron-deficiency anemia have a gastrointestinal disorder, such as inflammatory bowel disease, inflammatory bowel syndrome, Crohn's disease, microscopic colitis (such as collagenous or lymphocytic colitis), or chemically-induced colitis (e.g., NSAID (nonsteroidal anti-inflammatory drug)-induced colitis). In certain aspects, the patients treated for iron-deficiency anemia have blood loss associated with childbirth, menstruation or infection. In some aspects, the patients treated for iron-deficiency anemia have insufficient dietary intake of iron and/or insufficient absorption of iron.
    Type: Application
    Filed: March 3, 2016
    Publication date: March 15, 2018
    Applicant: Keryx Biopharmaceuticals, Inc.
    Inventors: Enrique Poradosu, Ron Bentsur, Shay David Shemesh
  • Publication number: 20160256486
    Abstract: Methods of administering ferric citrate to reduce and/or control serum phosphorus levels, increase serum bicarbonate levels, improve one or more iron storage parameters (e.g., increase serum ferritin levels, increase transferrin saturation (TSAT), increase hemoglobin concentration), increase iron absorption, maintain iron stores, treat iron deficiency, treat anemia, reduce the need for IV iron, reduce the need for erythropoiesis-stimulating agents (ESAs), and/or reduce mortality and morbidity related to adverse cardiac events in chronic kidney disease patients, are disclosed.
    Type: Application
    Filed: November 3, 2014
    Publication date: September 8, 2016
    Applicant: Keryx Biopharmaceuticals, Inc.
    Inventors: Enrique Poradosu, Ron Bentsur, James F. Oliviero, III
  • Publication number: 20150079168
    Abstract: Methods of administering ferric citrate to reduce and/or control serum phosphorus levels, increase serum bicarbonate levels, improve one or more iron storage parameters (e.g., increase serum ferritin levels, increase transferrin saturation (TSAT), increase hemoglobin concentration) increase iron absorption, maintain iron stores, treat iron deficiency, treat anemia, reduce the need for IV iron and/or reduce the need for erythropoiesis-stimulating agents (ESAs) in chronic kidney disease patients, are disclosed.
    Type: Application
    Filed: October 24, 2014
    Publication date: March 19, 2015
    Applicant: KERYX BIOPHARMACEUTICALS, INC.
    Inventors: Enrique Poradosu, James F. Oliviero, III, Ron Bentsur
  • Publication number: 20140234416
    Abstract: Methods of administering ferric citrate to reduce and/or control serum phosphorus levels, increase serum bicarbonate levels, improve one or more iron storage parameters (e.g., increase serum ferritin levels, increase transferrin saturation (TSAT), increase hemoglobin concentration) increase iron absorption, maintain iron stores, treat iron deficiency, treat anemia, reduce the need for IV iron and/or reduce the need for erythropoiesis-stimulating agents (ESAs) in chronic kidney disease patients, are disclosed.
    Type: Application
    Filed: April 25, 2014
    Publication date: August 21, 2014
    Applicant: Keryx Biopharmaceuticals, Inc.
    Inventors: Enrique Poradosu, James F. Oliviero, III, Ron Bentsur
  • Publication number: 20130345303
    Abstract: Methods of administering ferric citrate to reduce and/or control serum phosphorus levels, increase serum bicarbonate levels, improve one or more iron storage parameters (e.g., increase serum ferritin levels, increase transferrin saturation (TSAT), increase hemoglobin concentration) increase iron absorption, maintain iron stores, treat iron deficiency, treat anemia, reduce the need for IV iron and/or reduce the need for erythropoiesis-stimulating agents (ESAs) in chronic kidney disease patients, are disclosed.
    Type: Application
    Filed: June 21, 2013
    Publication date: December 26, 2013
    Inventors: Enrique Poradosu, James F. Oliviero, III, Ron Bentsur
  • Patent number: 8383607
    Abstract: Treatment regimens comprising co-treatment of cancer with perifosine and capecitabine are disclosed herein, as well as pharmaceutical compositions and unit dosage forms thereof formulated to be suitable for use in said treatment regimens.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: February 26, 2013
    Assignee: AEterna Zentaris GmbH
    Inventors: Enrique Poradosu, Peeter Sportelli
  • Publication number: 20110243933
    Abstract: Treatment regimens comprising co-treatment of cancer with perifosine and capecitabine are disclosed herein, as well as pharmaceutical compositions and unit dosage forms thereof formulated to be suitable for use in said treatment regimens.
    Type: Application
    Filed: March 31, 2011
    Publication date: October 6, 2011
    Applicant: Keryx Biopharmaceuticals, Inc.
    Inventors: Enrique Poradosu, Peeter Sportelli
  • Publication number: 20070173479
    Abstract: The present invention concerns methods for the treatment of bladder related diseases and, in particular, inflammatory bladder diseases such as interstitial cystitis, by administration of sulodexide.
    Type: Application
    Filed: December 9, 2004
    Publication date: July 26, 2007
    Applicant: KERYX BIOPHARMACEUTICALS, INC.
    Inventor: Enrique Poradosu