Abstract: The invention broadly provides an implantable medical device comprising a liquid rope coil scaffold. The implant may consist essentially of the scaffold, where the scaffold is the implant and pores in the scaffold may incorporates one or more agents (i.e. drugs, growth factors), or the scaffold may comprise only part of the medical device, for example an implant that is partly or fully covered with a layer of the scaffold. The porosity of the scaffold may be tailored to suit the application, for example a porosity that is tailored to hold and release drug or biological molecules in vivo, a porosity to provide a surface roughness that is conducive to promotion of in-vivo bio-integration (for example vascularisation) or prevention of fibrosis, or a porosity that provides structural strength. The scaffold may be essentially tubular, or may be provided as a planar structure, or may be any shape and can be used to coat, fully or partially any shape or size of medical implant.

Abstract: A cell encapsulating implantable device, including: a cell chamber accommodating a plurality of biological cells disposed within a fluid, the cell chamber at least partially enclosed within an immuno-isolative membrane which permits diffusive exchange of nutrients between the fluid and a tissue in which the device is implanted for sustaining the plurality of biological cells, and the cell chamber being configured to accommodate flow of fluid therethrough.

Abstract: A stabilisation system for securing a medical device such as a catheter to tissue, in particular skin, the stabilisation system comprising a main body having a first section and a second section displaceable relative to one another to translate the system between an undeployed state and a deployed state, each section including an array of microneedles extending from a tissue contacting surface of the body and which penetrate the skin in response to the above displacement, the stabilisation system further comprising a closure member displaceable between an open position exposing a retention zone on the body and a closed position at least partially occluding the retention zone, within which retention zone the catheter or other medical device may be captured.

Abstract: An oral appliance (100) comprising a sensing arrangement (101) disposed in proximity to at least one part of a facial muscle complex of a user. A method of controlling the oral appliance (100) comprising sensing, with the sensing arrangement (101), the at least one part of the facial muscle complex being brought towards the sensing arrangement; and in response to sensing the at least one part of the facial muscle complex being brought towards the sensing arrangement (101), controlling the oral appliance (100) to perform an action. An external processing unit (200) is arranged to interact with the oral appliance (100) in response to the oral appliance (100) performing the action.

Abstract: The present invention provides a tissue anchor and a system and method employing same, the anchors including a body having a first section and a second section reversibly engagable with one another, each section including a plurality of barbs in the form of microneedles projecting from the underside therefore, the barbs on one section being inclined towards barbs on the other section, such that tissue may be captured and deformed between the barbs through displacement of the first section relative to the second section in order to achieve robust retention of the tissue anchor at a deployment site.

Abstract: The present application relates to a surgical delivery device (10) suitable for submucosal dye delivery or for introduction or extraction of fluidic or gaseous material into or from tissue (T), the surgical delivery device comprising an elongate main body (12) defining an evacuatable chamber (18) internally thereof, a lateral window (20) in the body in communication with the chamber and a guideway (24a) extending through the body and into the chamber.

Abstract: The present invention provides a tissue anchor and a system and method employing same, the anchors including a body having a first section and a second section reversibly engagable with one another, each section including a plurality of barbs in the form of microneedles projecting from the underside therefore, the barbs on one section being inclined towards barbs on the other section, such that tissue may be captured and deformed between the barbs through displacement of the first section relative to the second section in order to achieve robust retention of the tissue anchor at a deployment site.

Abstract: The present invention provides a stabilisation system for securing a medical device such as a catheter to tissue, in particular skin, the stabilisation system comprising a main body having a first section and a second section displaceable relative to one another to translate the system between an undeployed state and a deployed state, each section including an array of microneedles extending from a tissue contacting surface of the body and which penetrate the skin in response to the above displacement, the stabilisation system further comprising a closure member displaceable between an open position exposing a retention zone on the body and a closed position at least partially occluding the retention zone, within which retention zone the catheter or other medical device may be captured.

Abstract: The invention broadly provides an implantable medical device comprising a liquid rope coil scaffold. The implant may consist essentially of the scaffold, where the scaffold is the implant and pores in the scaffold may incorporates one or more agents (i.e. drugs, growth factors), or the scaffold may comprise only part of the medical device, for example an implant that is partly or fully covered with a layer of the scaffold. The porosity of the scaffold may be tailored to suit the application, for example a porosity that is tailored to hold and release drug or biological molecules in vivo, a porosity to provide a surface roughness that is conducive to promotion of in-vivo bio-integration (for example vascularisation) or prevention of fibrosis, or a porosity that provides structural strength. The scaffold may be essentially tubular, or may be provided as a planar structure, or may be any shape and can be used to coat, fully or partially any shape or size of medical implant.

Abstract: An oral appliance (100) comprising a sensing arrangement (101) disposed in proximity to at least one part of a facial muscle complex of a user. A method of controlling the oral appliance (100) comprising sensing, with the sensing arrangement (101), the at least one part of the facial muscle complex being brought towards the sensing arrangement; and in response to sensing the at least one part of the facial muscle complex being brought towards the sensing arrangement (101), controlling the oral appliance (100) to perform an action. An external processing unit (200) is arranged to interact with the oral appliance (100) in response to the oral appliance (100) performing the action.

Abstract: The present invention provides a tissue anchor and a system and method employing same, the anchors including a body having a first section and a second section reversibly engagable with one another, each section including a plurality of barbs in the form of microneedles projecting from the underside therefore, the barbs on one section being inclined towards barbs on the other section, such that tissue may be captured and deformed between the barbs through displacement of the first section relative to the second section in order to achieve robust retention of the tissue anchor at a deployment site.