Abstract: An apparatus for detecting anomalies of the skin, more particularly melanomae, includes a light source for illuminating a two-dimensionally extending examination region of the skin, successively, with ultraviolet light range and with visible light. A camera records a fluorescence picture of the examination region having signal values F(x,y) at its picture points x,y in response to the illumination with ultraviolet light and a reference picture having signal values R(x,y) at its picture points x,y in response to the illumination with visible light. A memory stores the signal values of at least one of the fluorescence picture and said reference picture, and a processor responsive to the memory produces an output picture having respective signal values A(x,y) at its picture points x,y which are formed from respective quotients F(x,y)/R(x,y) of the signal values of the fluorescence and reference pictures at the same picture points.