Patents by Inventor Erhardt Winkelmann

Erhardt Winkelmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4105763
    Abstract: New 1-methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles are disclosed as well as a process for their manufacture. The new compounds are suitable for the treatment of protozoal diseases and show a marked activity against helminths, ectoparasites and ticks.
    Type: Grant
    Filed: October 22, 1976
    Date of Patent: August 8, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 4078086
    Abstract: Novel compounds of anthraquinone-bis-amidines are prepared which are suitable for combating diseases caused by trichomonads.
    Type: Grant
    Filed: May 12, 1976
    Date of Patent: March 7, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 4057634
    Abstract: New (1-alkyl-5-nitro-imidazolyl-2-alkyl)-heteroaryl compounds are disclosed as well as a process for their manufacture.The new compounds are effective against pathogens, such as bacteria and protozoa, as well as against fungi.
    Type: Grant
    Filed: June 23, 1976
    Date of Patent: November 8, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Akhileswer Sinharay, Wolfgang Raether
  • Patent number: 4053482
    Abstract: Certain 1-methyl-2-(substituted thiomethyl)-5-nitro-imidazoles are described as well as a process for their manufacture. The compounds are suitable for the treatment of protozoal diseases, especially of trichomoniasis and of fungus diseases, especially dermatomycoses.
    Type: Grant
    Filed: April 7, 1976
    Date of Patent: October 11, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 4046896
    Abstract: The invention provides 1-methyl-2-(pyridyl-oxymethyl)-5-nitro-imidazoles and processes for preparing them. The compounds are useful in the therapy of diseases provoked by protozoa.
    Type: Grant
    Filed: May 14, 1976
    Date of Patent: September 6, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 4042705
    Abstract: 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles and a process for preparing them are disclosed. The compounds of the invention are suitable for the treatment of protozoal diseases caused in humans and animals and of bacteria and fungi.
    Type: Grant
    Filed: July 9, 1976
    Date of Patent: August 16, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 4031232
    Abstract: 1-Alkyl-2-(phenoxymethyl)-5-nitro-imidazoles are described as well as a process for their manufacture. The compounds are active against trichomonads and amoebae and are especially suitable for the treatment of Fluor genitalis.
    Type: Grant
    Filed: December 15, 1975
    Date of Patent: June 21, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 4018792
    Abstract: Novel 5-cyano-thiophen-2-aldehyde-isothiosemicarbazones are described as well as a process for their manufacture. These compounds are active against viruses and therefore suitable for the prophylaxis and therapy of corresponding infections in humans and animals.
    Type: Grant
    Filed: February 24, 1975
    Date of Patent: April 19, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Heinrich Rolly
  • Patent number: 4001415
    Abstract: New 1-alky-2-(pyridyl-sulfinylmethyl)-5-nitro-imidazoles and 1-alkyl-2-(pyridyl-sulfonylmethyl)-5-nitro-imidazoles are described according to the formula I ##STR1## in which R stands for a methyl, ethyl or hydroxyethyl group and Z stands for a --SO-- or --SO.sub.2 -- group and the pyridine ring is linked to the sulfinyl or the sulfonyl group in 2, 3 or 4 position as well as a process for their manufacture.The novel compounds have a pronounced activity against protozoae, especially trichomonads and amebae.
    Type: Grant
    Filed: September 4, 1975
    Date of Patent: January 4, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 3992397
    Abstract: New (1-alkyl-5-nitro-imidazolyl-2-alkyl)-heteroaryl compounds and process for their manufacture are described. The new compounds are well compatible and are effective against bacteria and protozoa as well as against fungi. They are especially active against trichomonads and amebae.
    Type: Grant
    Filed: December 12, 1974
    Date of Patent: November 16, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 3991191
    Abstract: New (1-alkyl-5-nitro-imidazolyl-2-alkyl)-heteroaryl compounds are disclosed as well as a process for their manufacture.The new compounds are effective against pathogens, such as bacteria and protozoa, as well as against fungi.
    Type: Grant
    Filed: January 22, 1975
    Date of Patent: November 9, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Akhileswer Sinharay, Wolfgang Raether
  • Patent number: 3984560
    Abstract: This invention provides 1-alkyl-2-(pyridylthiomethyl)-5-nitro-imidazoles and 1-alkyl-2-(N-oxy-pyridylthiomethyl)-5-nitro-imidazoles of the formula ##SPC1##In which R is methyl, ethyl or hydroxyethyl and the pyridyl and N-oxy-pyridyl group is linked in 2-, 3- or 4-position to the sulfur atom, as well as process for the manufacture of these compounds.The novel compounds are suitable for the treatment of protozoal diseases in mammals.
    Type: Grant
    Filed: September 4, 1975
    Date of Patent: October 5, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 3984426
    Abstract: (1-ALKYL-5-NITRO-IMIDAZOLYL-2-ALKYL)-HETEROARYL COMPOUNDS AND A PROCESS FOR THEIR MANUFACTURE ARE DESCRIBED. The new compounds are well compatible and are effective against bacteria and protozoa as well as against fungi. They are especially active against trichomonads and amebae.
    Type: Grant
    Filed: November 27, 1974
    Date of Patent: October 5, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 3973019
    Abstract: 1,4-BIS-5'-NITROIMIDAZOLYL-2'-METHYLENE-IMINO) PIPERAZINES OF THE FORMULA ##SPC1##In which R.sub.1 is hydrogen, methyl, ethyl or 2-hydroxyethyl and R.sub.2 is hydrogen or methyl, are prepared by reaction of 5-nitro-imidazolyl-2-aldehydes or the functional derivatives thereof with 1,4-diamino-piperazines. Pharmaceutical compositions containing these compounds for treating protozoal diseases and methods of treating protozoal diseases with these compounds are disclosed.
    Type: Grant
    Filed: December 20, 1974
    Date of Patent: August 3, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Raether
  • Patent number: 3962454
    Abstract: Bis-(1-alkyl-5-nitro-imidazolyl)-compounds as well as a process for their manufacture are described. The compounds are active against protozoal diseases.
    Type: Grant
    Filed: February 19, 1975
    Date of Patent: June 8, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Wolfgang Baether
  • Patent number: 3951963
    Abstract: Novel 0-(dialkylaminoalkyl)-1-alkyl-5-nitroimidazole-(2)-aldoximes are described as well as their manufacture and use for treating protozoal diseases. The novel compounds correspond to the general formula ##SPC1##In which R.sup.1 stand for a hydrogen atom, a methyl, ethyl or hydroxyethyl group, Z stands for a linear or branched alkylene chain of 2 to 3 carbon atoms, and R.sup.2 and R.sup.3 each stands for an identical or different lower alkyl radical having from 1 to 4 carbon atoms or the group --NR.sup.2 R.sup.3 can be part of a saturated heterocyclic ring which may contain further substituents preferably a methyl group or/and hetero atoms, such as, especially the pyrrolidine, piperidine, morpholine, thiamorpholine, tetrahydro-1,4-thiazine-1,1-dioxide and piperazine ring, and HX can be a non-toxic, physiologically acceptable acid.
    Type: Grant
    Filed: March 5, 1974
    Date of Patent: April 20, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erhardt Winkelmann, Ulrich Gebert, Wolfgang Raether
  • Patent number: 3950539
    Abstract: Substituted diamino-guanidines are described as well as their manufacture and their use as medicaments against protozoa, especially against coccidiosis.
    Type: Grant
    Filed: February 19, 1975
    Date of Patent: April 13, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Militzer, Erhardt Winkelmann, Wolfgang Raether